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Researchers at the University of Michigan Rogel Cancer Center designed this new delivery system -- a drug hidden in a nanodisc -- to increase the number of patients who can be treated successfully with cancer immunotherapy drugs.
Selective breeding just before and during the Iron Age nearly 3,000 years ago is likely the reason for the lack of variability in modern domestic horses' paternally inherited DNA, a trait unique among livestock animals.
Scientists have created a biomedical tattoo that becomes visible on the skin of mice in response to elevated levels of calcium in the blood.
A new study has revealed a previously undocumented process where melting glacial ice sheets change the ocean in a way that further accelerates the rate of ice melt and sea level rise.Led by IMAS PhD student Alessandro Silvano and published in the journal Science Advances, the research found that glacial meltwater makes the ocean's surface layer less salty and more buoyant, preventing deep mixing in winter and allowing warm water at depth to retain its heat and further melt glaciers from below.
Southwest Research Institute scientists posit a violent birth of the tiny Martian moons Phobos and Deimos, but on a much smaller scale than the giant impact thought to have resulted in the Earth-moon system. Their work shows that an impact between proto-Mars and a dwarf-planet-sized object likely produced the two moons, as detailed in a paper published today in Science Advances.
An international team focused on HIV cure research spearheaded by The Wistar Institute in collaboration with the University of Pennsylvania and Vall d'Hebron Research Institute (VHIR) in Barcelona, Spain, established that the CD32 molecule is not a preferential biomarker to identify HIV silent reservoirs within the immune system of patients undergoing antiretroviral therapy (ART), as proposed by a recent landmark study.
Americans waste nearly a pound of food per person each day, but the exact amount of food we trash differs by how healthy your diet is, a new PLOS ONE study finds. Between 2007-2014, consumers wasted nearly 150,000 tons of food per day. Researchers estimate that food waste corresponded with the use of 30 million acres of land (7 percent of total US cropland) and 4.2 trillion gallons of water annually.Higher quality diets were associated with higher levels of food waste.
Online exchanges, such as Craigslist, may not just help consumers declutter and earn a few extra bucks -- a Penn State researcher suggests that using those exchanges may help inspire behavior that is good for the environment.
People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers. They found that people with obesity had a 40 percent higher chance of developing atrial fibrillation than people without obesity.
By using a keyboard for tactile feedback in combination with a screen reader, users were three times more successful at navigating complex modern webpages, like they would encounter in a typical Airbnb booking site.
A compound from the body's own immune cells can treat psoriasis in mice and holds promise for other autoimmune diseases such as multiple sclerosis, according to a new study at Washington University School of Medicine in St. Louis.
A new study published online today in Nature shows that corals on the northern Great Barrier Reef experienced a catastrophic die-off following the extended marine heatwave of 2016.
Researchers at the University of Colorado Boulder have completed an unprecedented 'dissection' of twin galaxies in the final stages of merging. The new study, led by CU Boulder research associate Francisco Müller-Sánchez, explores a galaxy called NGC 6240. While most galaxies in the universe hold only one supermassive black hole at their center, NGC 6240 contains two -- and they're circling each other in the last steps before crashing together.
A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger.
Scientists identified a neural circuit in the hypothalamus as the primary mechanism mediating the hormone leptin's anti-obesity and anti-diabetes effects and found two mechanisms underlying leptin's inhibition of appetite. The work in mice advances efforts to treat human obesity and diabetes.
Together with colleagues from Munich and Mainz, researchers at the Physikalisch-Technische Bundesanstalt (PTB) have performed the first-ever optical measurements of some important properties of the low-energy state of the Th-229 nucleus. In this way, a laser excitation of the atomic nucleus can be monitored, thus allowing an optical nuclear clock to be realized that 'ticks' more precisely than present-day atomic clocks. The scientists have reported their results in the current issue of Nature.
Protected areas for sage grouse don't necessarily serve the needs of other species that depend on sagebrush habitat, showing that the bird might not be as much of an umbrella species as had been assumed.
Interruptions in workflow, such as a phone call while working on another task, or when a colleague stops by for a chat, can lead to inefficiencies in the workplace. Now, a study from the University of Missouri has determined that workflow interruptions are most likely to occur during two key events -- electronic medical record documentation and direct patient care. Findings suggest that changes in workflow in emergency departments could increase the care team's efficiency and help improve patient care.
Studies at the University of Tennessee Institute of Agriculture are identifying plant physiological traits that could minimize the effect of drought in row crops.
A new study in The Lancet Public Health shows the rapid expansion of British Columbia's Take Home Naloxone program significantly reduced the number of fentanyl-related overdose deaths in 2016.