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Updated: 5 min 10 sec ago
Despite the great successes of targeted cancer drugs and the promise of novel immunotherapies, the vast majority of people diagnosed with cancer are still first treated with chemotherapy. Now a new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use the genetic profile of a patient's tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.
As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the Abramson Cancer Center are providing clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.
Hotspots of type 1 diabetes in New York City are found in food swamps, areas with a higher proportion of fast food restaurants, for children and adults with type 1 diabetes (T1D), according to a new study published in the Endocrine Society's Journal of the Endocrine Society.
Children in sub-Saharan African settings with uncomplicated fever may be safely managed with conditional, rather than universal, three-day follow-up with a community health worker (CHW), according to two cluster-randomized, community-based non-inferiority trials published this week in PLOS Medicine.
New research using manipulated audio clips from NPR's Science Friday and YouTube videos of academic presentations indicates that poor audio quality can create distrust -- in both the information and the source, while high audio quality strengthens their credibility.
A research team, led by scientists from Arizona State University and funded by NASA and the National Science Foundation, is helping to understand why the Permian-Triassic mass extinction event happened and why it took life so long to recover.
Researchers at the University of Pittsburgh are developing new ways to store, separate, and transport gases. Their recently published study 'Thermal Transport in Interpenetrated Metal-Organic Frameworks' appeared in the American Chemical Society journal Chemistry of Materials. The issue's cover also featured an image designed by Kutay Sezginel, a chemical engineering graduate student in Dr. Wilmer's Lab. It depicted interpenetrated metal organic frameworks or MOFs.
An Oxford University study published in Nature advises that people's digital remains, such as, social media activity and online history, should be viewed in the same way as the human body, and treated with care and respect rather than manipulated for commercial gain.The paper suggests regulation akin to those used in museums and commercial use of organic human remains, is the best way to create explicit boundaries around acceptable afterlife activity and grief exploitation.
Researchers at University of California San Diego School of Medicine have determined that psychological resilience has a positive effect on health outcomes for people living with schizophrenia. This is the first study to quantitatively assess the effects of both childhood trauma and psychological resilience on health and metabolic function in people living with schizophrenia. The findings are published in the April 17 online issue of the Journal of Clinical Psychiatry.
New research from experts in history, computer science and cognitive science shines fresh light on the French Revolution, showing how rhetorical and institutional innovations won acceptance for the ideas that built the French republic's foundation and inspired future democracies.
Shortly after they turn 1, most babies begin to help others, whether by handing their mother an object out of her reach or giving a sibling a toy that has fallen. Researchers have long studied how this helping behavior develops, but why it develops has been examined less. A new study looked at the role of imitation to find that when 16-month-olds observe others' helping behavior, they're more likely to be helpful themselves.
In a preliminary study presented at the American Association for Cancer Research Annual Meeting 2018 in Chicago, researchers from the UNC Lineberger Comprehensive Cancer Center revealed findings for what kind of immune response the body is staging against triple negative breast cancer that has spread to the brain. They hope they can use these findings to improve patient responses to drugs that work by unleashing the immune system against cancer.
MIT CSAIL's 'RoadTracer' system could reduce workload for developers of apps like Google Maps
A team of researchers from Lobachevsky University (Nizhny Novgorod, Russia) headed by Professor Alexei Fedorov, Chair of the Organic Chemistry Department, is working to create a new generation of targeted anti-cancer drugs for photodynamic therapy.
A blood test to measure the levels of two proteins in plasma that are common predictors of lung cancer was 98 percent effective in a multicenter clinical trial at distinguishing benign from malignant lung nodules when combined with a patient's clinical characteristics to form an integrated classifier. These results were reported by a team of investigators at the Medical University of South Carolina in an article in Chest.
A team of scientists headed by Rosalind Franklin University Professor David M. Mueller, Ph.D., has solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells.
In a new study, researchers decided to examine the role that skilled nursing facilities (SNFs) play with regard to older adults' placements in long-term care facilities.
Cholesterol-lowering drugs are more likely to save thousands of additional lives when used in people with higher levels of LDL cholesterol, or 'bad' cholesterol, according to a new study from the University of Iowa, published in the Journal of the American Medical Association (JAMA).
Listeria costaricensis is the official name given to the new bacterial species described by investigators from the Costa Rican Institute of Technology and the WHO-collaborating center on Listeria at Institut Pasteur.
Agricultural economists at the University of Illinois wanted to learn more about the productivity of grain production in the tropics. In a study published in the International Journal of Agricultural Management, they examine input and output factors for several large-scale farms located in the state of Mato Grosso, Brazil.