Changing how primary-care doctors treat pain, fatigue and other common symptoms

Changing how primary-care doctors treat pain, fatigue and other common symptoms

INDIANAPOLIS -- Common symptoms such as pain or fatigue account for over half of all doctor's office appointments in the United States, translating into more than 400 million visits annually.

A new study from the Regenstrief Institute and Indiana University School of Medicine reports that one in three common symptoms do not have a clear-cut disease-based explanation. The study also offers suggestions on how doctors can help patients deal more effectively with both physical and psychological symptoms.

New study charts the fate of chemicals affecting health and the environment

New study charts the fate of chemicals affecting health and the environment

Looking forward in science often requires looking back, evaluating trends to extrapolate future outcomes. A classic case is Moore's Law, which predicts that the density of components on an integrated circuit will double every 24 months. The estimate has helped guide many developments in the computer industry.

In a new study, Rolf Halden, PhD, a researcher at Arizona State University's Biodesign Institute, examines the trajectory of chemicals appearing as emergent threats to human or environmental health.

Researchers confirm the biochemical cause of seasonal depression

Berlin, 21 October 2014 New research confirms why some people suffer from the winter blues while others get through the winter without any problems. A longitudinal study from a group of researchers from the University of Copenhagen has found that that people with Seasonal Affective Disorder (SAD) show significant seasonal differences in the way they regulate the neurotransmitter serotonin in comparison to the majority of the population. This work is being presented at the ECNP congress in Berlin.

Three-minute assessment successfully identifies delirium in hospitalized elders

BOSTON -- Delirium is a state of confusion that develops suddenly, often following an acute medical illness, a surgical procedure or a hospitalization. Although delirium is estimated to complicate hospital stays for over 2.5 million elderly individuals in the U.S. each year, this common condition often goes undetected. The end result can be serious complications with sometimes devastating consequences for vulnerable hospitalized elders.

Gambling, hypersexuality, compulsive shopping associated with dopamine agonist drugs

Bottom Line: During a 10-year period, there were 1,580 adverse drug events reported in the United States and 21 other countries that indicated impulse control disorders in patients, including 628 cases of pathological gambling, 465 cases of hypersexuality and 202 cases of compulsive shopping. The total included 710 events associated with dopamine receptor agonist drugs (used to treat Parkinson disease, restless leg syndrome and hyperprolactinemia) and 870 events for other drugs.

For prescription drug addiction treatment, buprenorphine maintenance trumps detoxification

For treating patients with prescription opioid dependence in primary care, buprenorphine maintenance therapy is superior to detoxification, according to a new study by Yale School of Medicine researchers published in the Oct. 20 issue of JAMA Internal Medicine.

Obesity link to increased risk for orthopedic conditions and surgical complications

ROSEMONT, Ill.—Obesity affects individual patient care, the healthcare system and nearly every organ in the body. People with obesity often have other health problems, including diabetes, heart disease, certain tumors and cancers, and psychiatric disorders. However, the role of obesity in orthopaedic conditions and their treatment is less well-publicized.

Research reveals likelihood, onset of MS diagnosis among patients with inflammatory eye disease

Biomarkers uPA/PAI-1 in breast cancer: Benefit and harm of the test unclear

To make a decision for or against adjuvant chemotherapy, a test to measure the concentrations of the biomarkers uPA and PAI-1 in the tumour tissue is available for breast cancer patients. However, as suitable studies are lacking, it remains unclear for patients with an intermediate risk of recurrence which benefit or harm a treatment strategy based on this test may have for them. This is the result of the final report published by the Institute for Quality and Efficiency in Health Care (IQWiG) on 20 October 2014.

Adjuvant systemic treatments aim to prolong survival

No added benefit proven for umeclidinium/vilanterol in COPD

The drug combination umeclidinium/vilanterol (trade name Anoro) has been approved since May 2014 for adults with chronic obstructive pulmonary disease (COPD). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this drug combination offers an added benefit over the appropriate comparator therapy.