Eurekalert

A major challenge in cancer therapy is the adaptive response of cancer cells to targeted therapies. Although this adaptive response is theoretically reversible, such a reversal is hampered by numerous molecular mechanisms that allow the cancer cells to adapt to the treatment. A team (UNIGE/HUG) has used information theory, in order to objectify in vivo the molecular regulations at play in the mechanisms of the adaptive response and their modulation by a therapeutic combination.

Recently, metal halide perovskite solar cells (PSCs) have attracted world-wide interest due to their high power conversion efficiency of 25.5% and great potential in becoming a disruptive technology in the photovoltaic industry. Scientists in China summarized current challenges and strategies for the fabrication of PSCs by printing techniques. Moreover, the stability of perovskite solar modules has been discussed and analyzed.

St. Jude Children's Research Hospital scientists have shown that frailty contributes to neurocognitive decline in young adult survivors of childhood cancer.

Researchers are the first to model COVID-19 completion versus cessation in clinical trials using machine learning algorithms and ensemble learning. They collected 4,441 COVID-19 trials from ClinicalTrials.gov to build a testbed with 693 dimensional features created to represent each clinical trial. These computational methods can predict whether a COVID-19 clinical trial will be completed or terminated, withdrawn or suspended. Stakeholders can leverage the predictions to plan resources, reduce costs, and minimize the time of the clinical study.

A new study from Oregon State University found that infants born within 3 kilometers of oil and natural gas drilling facilities in Texas had slightly lower birthweights than those born before drilling began in their vicinity.

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

Regulatory T cells (Tregs) help control inflammation and autoimmunity in the body. Unfortunately, it has proven difficult to find the right molecular ingredients to induce stable iTregs. Now a new study reports that Vitamin C and TET proteins can work together to give Tregs their life-saving power.

Older adults may be slower to learn actions and behaviours that benefit themselves, but new research shows they are just as capable as younger people of learning behaviours that benefit others.

Imagine meeting a friend on the street, and imagine that with every step they take, your visual system has to process their image from scratch in order to recognize them. Luckily, our visual system is able to retain information obtained in motion, thereby presenting us with a consistent picture of our surroundings. These are the findings of a study conducted by SISSA, in collaboration with the Penn and KU Leuven and published in Nature Communications, which explains the neuronal underpinnings of this phenomenon.

Small increases in daily physical activity after receiving an implantable cardioverter defibrillator (ICD) were associated with decreases in hospitalizations and deaths among adults over age 65 with heart failure.For every 10 minutes a day of increased physical activity, there was a 1% lower risk of death and hospitalization.

Babies who were breastfed, even for a few days, had lower blood pressure at 3 years of age than children who had never been breastfed.Toddlers who had been breastfed had lower blood pressure regardless of their body mass index or their mothers' social, health or lifestyle factors.

Sweeping changes in marine nutrients may seem to be a likely consequence of increasing global temperatures; however, new research suggests that processes below the ocean surface could play a larger role than previously thought.

Smartphone gaming can be harmful to players who game to escape their negative mood and feelings of boredom, a new study has found.

Forensic scientists have developed a new method to help monitor plastic pollution across the world. An adhesive tape patented by Staffordshire University researchers to recover trace evidence from crimes scenes is being adopted to analyse microplastics more efficiently.

Students who participated in a meditation-based Quiet Time program utilizing the Transcendental Meditation (TM) technique for four months had significant improvements in overall emotional stress symptoms, quality of sleep, and English Language Arts (ELA) academic achievement according to a new randomized controlled trial published last month in Education. This was the first randomized control trial to investigate the effects of TM on standardized academic tests.

Whether summer or winter, midnight sun or polar night - the sand on the ocean floor is always inhabited by the same bacteria. Although the microbial communities differ between different ocean regions, they do not change between the seasons. Presumably, there is simply no room for change. Researchers at the Max Planck Institute for Marine Microbiology in Bremen, Germany, now describe this phenomenon in a study published in the journal ISME Communications.

New research unveils that firms connected to organized crime have lower return on assets, higher debt, lower cash holdings and are more likely to default.

These Oncotarget results may reflect the unselected patient population enrolled in these studies, including no selection for WHO histologic subtype or molecular aberrations.

Twenty-nine percent of Americans are taking more supplements today than they were before the COVID-19 pandemic, bringing the percentage of supplement-takers to 76%, according to a new Harris Poll survey on behalf of Samueli Foundation. Nearly two-thirds of those who increased supplement use (65%) sought enhanced overall immunity (57%) or COVID-19 protection (36%). Other common reasons were to take their health into their own hands (42%) or to improve sleep (41%) or mental health (34%).

A 16-year study has revealed a link between cognitive decline, bone loss and fracture risk in women.