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The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.
Updated: 2 years 7 months ago

Characterized drugs show unexpected effects

Jul 22 2021 - 00:07
Every drug starts with the search for an active substance targeting disease-related key players. However, there is no perfect drug that affects the one target: no effect without side effects. A group led by Prof. Herbert Waldmann and Dr. Slava Ziegler at the Max Planck Institute of Molecular Physiology in Dortmund has now identified an unexpected effect for a group of characterized active substances: they all modulate cholesterol metabolism, a home-made problem, as it seems.
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Interaction identified between SARS-CoV-2 and unusual RNA structures in human cells

Jul 22 2021 - 00:07
Replication of SARS-CoV-2, the virus responsible for COVID-19, depends on a series of interactions between viral proteins and different cellular partners such as nucleic acids (DNA or RNA). Characterizing these interactions is crucial to elucidate the process of viral replication and identify new drugs for treating COVID-19.
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Artificial intelligence models to analyze cancer images take shortcuts that introduce bias

Jul 22 2021 - 00:07
A new study led by researchers from the University of Chicago shows that deep learning models trained on large sets of cancer genetic and tissue histology data can easily identify the institution that submitted the images.
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Parkinson's disease: How lysosomes become a hub for the propagation of the pathology

Jul 22 2021 - 00:07
Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases. A team of researchers found out the implication of lysosomes in the spread of Parkinson's disease.
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Antimatter from laser pincers

Jul 22 2021 - 00:07
An international physics team with the participation of the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) has proposed a new concept that may allow selected cosmic extreme processes to be studied in the laboratory in the future. A special setup of two high-intensity laser beams could create conditions similar to those found near neutron stars, for example. An antimatter jet is generated and accelerated very efficiently, as the experts report in the journal Communications Physics (DOI: 10.1038/s42005-021-00636-x).
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Scientists reverse age-related memory loss in mice

Jul 22 2021 - 00:07
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age.
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Surgeons endorse efforts to improve firearm safety and reduce firearm-related injuries

Jul 22 2021 - 00:07
In what may be the largest survey of physician attitudes about firearms and how firearm-owning surgeons store guns in their homes, U.S. members of the American College of Surgeons (ACS) said they support the organization taking an active role in advocating for policies and programs designed to lower the risk of firearm-related injuries and deaths.
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Survival after cardiac arrest - Freiburg cardiovascular surgeons develop new technique

Jul 22 2021 - 00:07
German researchers have developed a novel therapeutic approach for resuscitation after cardiac arrest that allows much higher success rates than before - often without neurological complications / Study in Nature Reviews Neuroscience summarizes decisive factors / New „heart-lung machine" makes clinical implementation possible.
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Unlocking genetic clues behind aortic aneurysm

Jul 22 2021 - 00:07
After examining nearly the entire human genome for genetic changes that increase risk of aneurysm, researchers discovered a new change in the genetic code of a transcription factor.
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New insight on the reproductive evolution of land plants

Jul 22 2021 - 00:07
International consortium, including then IGC, now current ITQB NOVA PI and GREEN-IT member Jörg Becker, offers novel insight into the reproductive evolution of land plants, in new study published in Nature Plants.
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New study reveals previously unseen star formation in milky way

Jul 22 2021 - 00:07
A new survey of our home galaxy, the Milky Way, combines the capabilities of the Very Large Array and the Effelsberg telescope in Germany to provide astronomers with valuable new insights into how stars much more massive than the Sun are formed.
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A rock with many perspectives

Jul 22 2021 - 00:07
The chequered history of the Cambro-Ordovician Alum Shale in northern Europe offers insights into oil and gas formation and traces of life on Mars.
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Cardio-cerebrovascular disease history complicates hematopoietic cell transplant outcomes

Jul 22 2021 - 00:07
Transplanting hematopoietic stem cells to treat cancers and other conditions carries with it the risk of developing cardio-cerebrovascular diseases (CCVD)--disorders affecting the blood vessels of the heart and brain. Although research on post-transplant CCVD is extensive, there is paucity of knowledge on the effects of pre-transplant CCVD on transplant outcomes. Now researchers in China suggest pre-transplant CCVD indirectly affects patient mortality and survival following transplant through their strong association with post-transplant CCVD.
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Generation and application of the high-Q resonance in all-dielectric metasurfaces

Jul 22 2021 - 00:07
In a new publication from Opto-Electronic Advances; DOI 10.29026/oea.2021.200030 , Researchers led by Professor Liu Yan from Xidian University, China and Professor Gan Xuetao from Northwestern Polytechnical University, China consider generation and application of the high-Q resonance in all-dielectric metasurfaces.
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Burden of oral diseases in emerging countries: A prediction model

Jul 22 2021 - 00:07
Jiachen Lin, Harvard School of Dental Medicine, Boston, Mass., USA., presented the poster "Burden of Oral Diseases in Emerging Countries: A Prediction Model" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
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New study reports strong indications of freshened groundwater offshore the Maltese Islands

Jul 22 2021 - 00:07
An international team of scientists has reported strong indications of freshened groundwater offshore the coastline between Valletta and Marsascala, in the south-east of Malta.
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Longitudinal serological and vaccination responses to SARS-COV-2 in dental professionals

Jul 22 2021 - 00:07
Alexandria, Va., USA - Iain Chapple, University of Birmingham, England, presented the oral session "Longitudinal Serological and Vaccination Responses to SARS-COV-2 in Dental Professionals" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
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Cannabidiol promotes oral ulcer healing by inactivating CMPK2-mediated NLRP3 inflammasome

Jul 22 2021 - 00:07
Xingying Qi, West China Hospital of Stomatology, Sichuan University, Chengdu, China, presented the oral session "Cannabidiol Promotes Oral Ulcer Healing by Inactivating CMPK2-Mediated NLRP3 Inflammasome" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
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Informing policy for long-term global food security

Jul 22 2021 - 00:07
More than 820 million people in the world don't have enough to eat, while climate change and increasing competition for land and water are further raising concerns about the future balance between food demand and supply. The results of a new IIASA-led study can be used to benchmark global food security projections and inform policy analysis and public debate on the future of food.
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New insights into uncontrolled inflammation in COVID-19 patients

Jul 22 2021 - 00:07
Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.
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