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PROVIDENCE, R.I. [Brown University] -- Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse. A new study by Brown University researchers is the first to reveal key physical properties of these "giant" cancer cells.

WORCESTER, MA - Reports from cannabis users that the drug reduces the symptoms of inflammatory bowel disease (IBD) may finally be explained by new research from the University of Massachusetts Medical School and the University of Bath showing that endocannabinoids help control and prevent intestinal inflammation in mice.

Women with intellectual and developmental disabilities have nearly double the rate of having another baby within a year of delivering compared to women without such disabilities, according to a new study published in CMAJ (Canadian Medical Association Journal).

To encourage innovation in health care, governments need to move away from current siloed funding to funding that encourages collaboration among providers in managing patients who need care in a variety of settings, argue the authors of an analysis in CMAJ (Canadian Medical Association Journal)

A Kaiser Permanente study of more than 80,000 children born over a 4-year period showed that the prenatal Tdap vaccination (tetanus, diphtheria, acellular pertussis) was not associated with increased risk of autism spectrum disorder in children. The study was published today in Pediatrics.

Philadelphia, August 13, 2018 - The incidence of coronary artery compression in children fitted with epicardial pacemakers may be slightly more common than previously believed, say noted cardiologists. After reviewing patient records at Boston Children's Hospital, they advocate for stricter monitoring to identify patients at risk and prevent complications.

A new LSU Pennington Biomedical Research Center study reveals that a novel biomarker might give us new answers necessary to creating a diagnostic tool for hypoglycemia-associated autonomic failure (HAAF). No objective diagnostic tool currently exists for this condition which, if left untreated, can lead to ever-worsening and possibly life-threatening episodes of dangerously low blood sugar.

A new type of bed net could prevent millions of cases of malaria, according to new research published in The Lancet today (10 August).

The two-year clinical trial in Burkina Faso, West Africa involving 2,000 children showed that the number of cases of clinical malaria was reduced by 12 per cent with the new type of mosquito net compared to the conventional one used normally.

WHAT:

Despite promising advances, important scientific questions remain unanswered in the effort to develop a safe and effective Ebola vaccine, according to members of an international Ebola research consortium. In a Viewpoint published in The Lancet, the experts review the current field of Ebola vaccine candidates and clinical trials and highlight key gaps in knowledge that need to be addressed by future research.

BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care.