Body

Chicago-May 7, 2019 - A new study released by the Center for Nutrition Research at Illinois Institute of Technology suggests that meals that include fresh avocado as a substitute for refined carbohydrates can significantly suppress hunger and increase meal satisfaction in overweight and obese adults.

As rates of obesity in the United States continue to rise, the findings from Illinois Tech suggest that simple dietary changes can have an important impact on managing hunger and aiding metabolic control.

Oncologists may soon have an accurate and inexpensive way of differentiating between types of ovarian cancer that will improve how patients are treated, thanks to findings from a national research study co-led out of the University of Alberta.

"One of the issues with ovarian cancer is that we cannot fully decipher between subtypes," said Lynne Postovit, U of A oncology researcher and co-director of the Cancer Research Institute of Northern Alberta. "This is an important problem because the different subtypes should be treated differently."

Philadelphia, May 8, 2019 - Grapefruit juice is already listed as a substance to avoid when taking QT-prolonging medications because it increases the toxicity of many drugs. Investigators have now confirmed the QT-prolonging effects of grapefruit juice in a new study and call for a stronger warning to patients who are taking QT-prolonging drugs or who have long QT syndrome because of the potential risk.

LEXINGTON, Ky. (May 8, 2019) -- Sepsis is a medical condition that few patients have heard of and most doctors dread. The body's response to attack by bacteria can trigger a cascade of cellular self-destruction that inadvertently causes blood clots, multi-organ failure, and death.

Fewer than half of men and women in Britain aged 16-44 have sex at least once a week, reveals a large study published by The BMJ today.

The data show a general decline in sexual activity in Britain between 2001 and 2012, with the steepest declines among the over 25s and those who are married or living together.

There is evidence that regular sexual activity is beneficial to health and wellbeing, but a recent decline has been seen in several high-income countries in the proportion of people who are sexually active, and how often they have sex.

Apgar scores of 7, 8, and 9 (considered to be within the normal range) are associated with higher risks of illness and even death in newborns, finds a large study from Sweden published by The BMJ today.

The odds of problems are increased with "normal" scores less than 10, but the researchers stress that the risk is still low and certainly lower than for babies with scores outside of the normal range.

Breast cancer is the most common cancer in the UK and is responsible for thousands of deaths each year. Ductal carcinoma in situ (DCIS) is a common type of breast cancer that does not spread, but can mutate over time to become metastatic cancer. DCIS is normally removed surgically, however there is a risk of recurrence after treatment, and it is currently difficult to predict this risk when assessing patients.

Potentially life-saving cancer risk assessment tools are being widely underused by general practices across the UK, according to new research.

A team of experts from the University of Exeter's Medical School has designed a set of risk assessment tools - which can predict the likelihood of undiagnosed cancer based on patients' symptoms, test results and other clinical information. Now, new NIHR-funded research has reviewed how well used the tools are within health practices.

WILMINGTON, Del. (May 7, 2019) - Researchers with Nemours Children's Health System have shown the effectiveness of an adult tourniquet for use in children, according to a study published today by the journal Pediatrics. While developed for adults, the military's Combat Application Tourniquet (CAT) is effective in controlling blood flow in children's arms and legs, as measured by Doppler pulse, in 100 percent of cases involving upper extremities and 93 percent for lower extremities. This is the first, prospective study on the device's use in children.

AUGUSTA, Ga. (May 7, 2019) - During big procedures like open heart surgery, patients need anticoagulants to prevent dangerous blood clot formation and regular bedside monitoring to make sure the drugs aren't also causing problems like excessive bleeding.

Investigators comparing some common bedside testing platforms to quickly determine how fast blood is clotting, called activated clotting time, or ACT, suggest other providers also compare results among the systems out there and use a more lengthy laboratory-based measure to confirm what they find.

DALLAS, May 7, 2019 - Drinking water that is contaminated with arsenic may lead to thickening of the heart's main pumping chamber in young adults, a structural change that increases the risk for future heart problems, according to new research in Circulation: Cardiovascular Imaging, an American Heart Association journal.

Indianapolis -- Regenstrief Institute research scientists are presenting some of the institute's latest research on patient engagement and advocacy at the Society of General Internal Medicine Annual Meeting in Washington, D.C., May 8-11.

The meeting covers the breadth and depth of general internal medicine. This year's theme is Courage to Lead: Equity, Engagement, and Advocacy in Turbulent Times. The conference gives Regenstrief researchers the opportunity to discuss how to advance health equity with other top researchers from around the country.

Leesburg, VA, May 6, 2019--A new technique for imaging of microbubble ultrasound contrast agents may be useful in detection of prostate cancer (PCa) not found by multiparametric magnetic resonance imaging (MRI), according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, HI.

The first in vivo application of contrast-enhanced SHI in the prostate, the pilot study was conducted to evaluate contrast-enhanced subharmonic imaging (SHI) of the prostate for detection of PCa.

An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients.

In a study published today in the New England Journal of Medicine, researchers from UBC and their colleagues have demonstrated for the first time that the drug, IONIS-HTTRX (now known as RO7234292) successfully lowered levels of the mutant huntingtin protein--the toxic protein that causes Huntington disease--in the central nervous system of patients.

Sometimes a little gentle peer persuasion goes a long way toward correcting a large problem.

That's the message from researchers at Johns Hopkins Medicine and seven collaborating health care organizations which report that a "Dear Colleague" performance evaluation letter successively convinced physicians nationwide to reduce the amount of tissue they removed in a common surgical treatment for skin cancer to meet a professionally recognized benchmark of good practice.