The assay has a clinically relevant five-day turnaround time and can be conducted on as little as 20 ng genomic DNA with a batch size of up to forty samples in a single run.
Assay performance with respect to accuracy, reproducibility, precision as well as control sample performance was estimated across a wide range of FFPE samples of multiple histologies to address pre-analytical variability, and analytical variability.
An easy-to-use electrode set can assess sleep bruxism severity as well as a conventional polysomnography, a new study from the University of Eastern Finland shows.
Sleep bruxism, commonly known as clenching or grinding of the teeth during sleep, affects approximately 8-15% of the population. Sleep bruxism can lead to various negative health consequences, such as tooth wear, facial pain and headaches. Sometimes, teeth grinding can be so loud that it disturbs the sleep of others in the same room.
The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer. Researchers at Children's Hospital Los Angeles are giving us a similar look into the anatomy of the human lung, and their findings could help babies breathe easier.
Molecule that protects plants from overexposure to light repurposed as a UV filter for sunscreen by University of Warwick scientists and team of collaborators
Disposes of harmful ultraviolet light using a superfast (100 billion twists a second) twist similar to the hand movements of flamenco dancers
One of a small number of molecules that could be used to protect against UVA light
Is eco-friendly and easy to synthesise
Would last far longer than many other sunscreens as it degrades 10 times slower in UVA light than the industry standard
Researchers at Karolinska Institutet in Sweden have developed a new cheap method that can identify highly heterogeneous tumours that tend to be very aggressive, and therefore need to be treated more aggressively. The technique is presented in the scientific journal Nature Communications.
According to a new study, published in the Journal of Clinical Endocrinology and Metabolism, health scientists at the Universities of Bath and Birmingham found that by changing the timing of when you eat and exercise, people can better control their blood sugar levels.
In the first analysis to estimate the gap between global supply and demand of blood, scientists have found that many countries are critically short of blood, according to a modelling study published in The Lancet Haematology journal.
The scourge of the influenza virus devastates health and claims many lives worldwide each year. It is especially daunting because vaccines are only protective when they are well matched to the strains circulating in the population. But now, a team led by researchers at the Icahn School of Medicine at Mount Sinai is getting closer to a universal flu vaccine using a novel approach they've developed called chimeric hemagglutinin (cHA).
Non-invasive brain stimulation is to be trialled for the first time alongside advanced brain imaging techniques in patients who are minimally conscious or in a vegetative state.
The study builds on promising results from the Centre for Human Brain Health at the University of Birmingham which suggested that non-invasive brain stimulation can improve the success of rehabilitation for non-responsive patients.
In 2010-2016, many U.S. transplant centers commonly accepted deceased donor kidneys with less desirable characteristics.
The use of these organs varied widely across transplant centers, however, and differences were not fully explained by the size of waitlists or the availability of donor organs.
LAWRENCE -- The neurological disorder FXTAS (pronounced "fax-tas") stems from a genetic premutation seen in one of every 151 women and one of every 468 men, called the FMR1 premutation.
MADISON -- Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems.
BOSTON - Autism spectrum disorders affect one in 59 American children by age eight. With no known quantitative biological features, autism diagnoses are currently based on expert assessments of behavioral symptoms, including impaired social skills and communication, repetitive behaviors and restricted interests.
LA JOLLA, CA - Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia. These diseases, which once would require a bone marrow transplant, can now be successfully treated by modifying patients' own blood stem cells to correct the underlying genetic problem.
(New York, NY - October 17, 2019) - Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.