Feed aggregator

In early 2018, colleagues and I released The Next Plague and How Science Will Stop It and coronavirus was in there, because there had already been two coronavirus pandemics, SARS and MERS, this century.

No one anticipated that SARS-CoV-2 would erupt in Wuhan, China, and be the worst pandemic since the 1950s but one thing I had long been concerned about was how unprepared the CDC was. Thanks to government becoming more overlords and less public servants - sorry, George Soros and friends, 'no kings' was a problem decades before President Trump was elected - and government employees spent their days grasping for more money rather than helping anyone.(1)

read more

A National Institute of Environmental Health Sciences paper(1) is sounding the alarm about detectable per- and polyfluoroalkyl substances (PFAS) in blood samples of Delaware residents.

It sounds scary, but scientifically there are two things to keep in mind:

1. We can detect anything in anything in 2025.
2. Presence is not pathology.

read more

Having interacted for a few months with ChatGPT 5 now, both for work-related problems and for private / self-learning tasks, I feel I might share some thoughts here on what these large models can tell us about our own thought processes. 

The sentence above is basically giving away my bottomline from square one, but I suppose I can elaborate a bit more on the concept. LLMs have revolutionized a wide range of information-processing tasks in just three or four years. Looking back, the only comparable breakthrough I can recall is the advent of internet search engines in the early 1990s. But as exciting and awesome this breakthrough is, it inspires me still more to ponder on how this is even possible. Let me unpack this.

read more

A survey asked 185 practicing transplant hepatologists across the U.S. who are among the American Association for the Study of Liver Diseases members across the U.S. about "unhealthy" alcohol use - alcohol is a class 1 carcinogen, so unless you eat healthy amounts of plutonium or smoke healthy amount of cigarettes 'unhealthy' is a strange qualifier only alcohol gets - and found 26.3 percent screened positive for way too much alcohol use.

Which is higher than the general United States population but ironic since hepatologists are gastroenterologists who focus on liver diseases and alcohol is the leading cause of liver disease. So common that they had to create a non-alcohol version for the rarer cases of fatty liver disease that don't involve drinking.

read more

If a politician who used to be a Natural Resources Defense Council lawyer hasn’t banned all food coloring by the time you read this, here is how you can make your own green slime. In both Gen X - chemicals that sound like chemicals - and more natural-sounding versions of chemicals. Basically, people who think Dawn dishwashing liquid is an organic weedkiller.

These are excerpted from Halloween Science 2.0, available on Amazon (and free if you have Kindle Unlimited)



Let’s post two ways. Both of these scale, depending on how much slime you want.

read more

Impostor participants are people who fake data in order to take part in health research or are  automated computer ‘bots’ which mimic human behavior and responses. As claims get promoted in journalism about harms related to PFAS in water, weedkillers causing cancer, or food coloring causing diabetes, lawsuits by predatory lawyers have become big business, and it won't be a surprise if such Predatorts or environmental and other activist groups are involved in fake participants to manipulate results in their favor.

read more

A new call to action by ecologists uses a numerical model to note that wildfires in places like California have been made worse by humans. 

That doesn't mean it is human emissions. For decades, California government has banned logging. They let people move to risky fire areas and then not pay for any mitigation or firebreaks. State and local governments refuse to allow dead brush to be cleared because it impacts the environment.

read more

Actors, artists, and musicians are rightly worried about the impact of AI on their incomes but doctors and scientists welcome the help. They know typewriters didn't make literature worse than writing in longhand and "AI" - LLMs - likewise removes the 'how' of information access so thinkers can get to the 'why.'

In modern government-controlled healthcare, doctors are more pressed for time per patient than ever. Often while relying on incomplete information. Electronic health records contain vast amounts of patient data but much of it remains difficult to interpret quickly, and that is even more challenging for patients with rare diseases or unusual symptoms.

read more

In the early days of Science 2.0, blogging did not get a lot of institutional respect. Public outreach was a waste of time, academics were often told, leave that to science journalists and the PIOs at schools who write press releases.

It seemed archaic. Anyone who knows how much of science is government-funded, about a third of basic research, knows that means it is political. Which means you cannot and should not let someone else write your narrative. It's too easy to manipulate. A decade ago, when a group wrote to Columbia University and asked them to remove Dr. Oz from the faculty because of his claims about supplements and that medicine was a corporate conspiracy, he got allies in corporate journalism to dismiss us as Big Pharma shills.(1)

read more

Due to President Clinton's 1994 DSHEA law (Dietary Supplement Health and Education Act of 1994), and diverting science funding to the National Center for Complementary and Alternative Medicine, a large number of people believe acupuncture works and that supplements can be alternatives to medicine.

Acupuncture is the placebo effect but some natural products can work - the problem is that if they work they may do something bad. Kratom is an example of a product banned in countries that grow it; unless it is for export to the United States. They know that it works, and also that it can kill Godzilla.

read more

From Los Angeles to Portland to New York City, political protests have become common. That provides data for what may be happening in brains and how engaged people can avoid becoming a Tyler Robinson or Luigi Mangione or Antifa in Oregon.

The US is not special when it comes to protests, the Carnegie Endowment for International Peace says there have been over 140 mass demonstrations globally in the past year, with 30 ongoing.

A new paper(1) says  up to 80% of activists experience moderate to severe anxiety or depression. Are they protesting because they are anxious or are they anxious because they spend time in a group of protesters? 

read more

When you picture a black hole, you probably picture in the center of a galaxy with matter swirling toward it. You're not wrong but that is why the exception proves the rule.

A recent study detected a surprising tidal disruption event where a black hole outside the center of a galaxy is tearing apart a star. Even stranger and defiance of black hole lore, the delayed and powerful radio outbursts suggest previously unknown processes in how black holes eject material over time. Designated AT 2024tvd, it is to-date the fastest-evolving radio emission ever observed from a black-hole-driven stellar disruption.

read more

A new study describes a new liquid phase in thin films of a glass-forming molecules. These results demonstrate how these glasses and other similar materials can be fabricated to be denser and more stable, providing a framework for developing new applications and devices through better design.

New research has identified potential treatment that could improve the human immune system's ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate the immune system, which in turn can unleash other immune cells to attack tumours in cancer patients.

University of Washington scientists have developed a statistical framework that incorporates key COVID-19 data -- such as case counts and deaths due to COVID-19 -- to model the true prevalence of this disease in the United States and individual states. Their approach projects that in the U.S. as many as 60% of COVID-19 cases went undetected as of March 7, 2021, the last date for which the dataset they employed is available.

Mice exposed to the opioid oxycodone before birth experience permanent changes in behavior and gene expression. The new research published in eNeuro highlights a need to develop safer types of painkillers for pregnant women.

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in Recent ultra-rare inherited variants implicate new autism candidate risk genes, a new study published in Nature Genetics.

An international team of researchers from the Max Planck Institute for Plant Breeding Research and the University of Åarhus in Denmark have discovered that bacteria from the plant microbiota are adapted to their host species. In a newly published study, they show how root-associated bacteria have a competitive advantage when colonizing their native host, which allows them to invade an already established microbiota.

A new study reports that among individuals who had an allergic reaction to their first mRNA COVID-19 vaccine dose, all who went on to receive a second dose tolerated it. Even some who experienced anaphylaxis following the first dose tolerated the second dose.

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.