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When I wrote Halloween Science 2.0, I wanted to get it down to a brisk 150 pages, which means taking a chainsaw to a lot of the material I had.(1)

Like the woman who left her corporeal significant other to become a ghost groupie. Amethyst Realm, that is not her Dungeons&Dragons name, she calls herself that for real, cheated on her totally organic fiancé with a ghost but she suggested it was kind of his fault. He moved them into a haunted house.

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There is legitimate concern about increased social authoritarianism in governments worldwide. The state has gained more financial control everywhere. Even in the U.S nearly 60% of wealth is controlled by politicians, and it is the most "capitalist" country.

It led to a culture where the American federal government forced employees to get a COVID-19 vaccine or be fired. Yet 20,000,000 government employees were not given that same ultimatum.
The same mentality has led to countries where companies in the organ transplant business want you to be an organ donor by law. It would create another schism in U.S. culture, where body autonomy remains an issue. There can be no body autonomy if the government can force you to donate your organs.

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The older you get, the more frail you become. The more frail you become, the greater the risk of falling, hospitalization, and shorter life expectancy.

Doctors talk about physical activity to reduce frailty but less attention is paid to biology. A new paper suggests that the hypothalamic–pituitary–gonadal (HPG) axis, the body’s system of regulating production of the hormone testosterone, can impact frailty.

"Suggests" means this is only EXPLORATORY, not human science, but a relationship between 

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In early 2018, colleagues and I released The Next Plague and How Science Will Stop It and coronavirus was in there, because there had already been two coronavirus pandemics, SARS and MERS, this century.

No one anticipated that SARS-CoV-2 would erupt in Wuhan, China, and be the worst pandemic since the 1950s but one thing I had long been concerned about was how unprepared the CDC was. Thanks to government becoming more overlords and less public servants - sorry, George Soros and friends, 'no kings' was a problem decades before President Trump was elected - and government employees spent their days grasping for more money rather than helping anyone.(1)

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A National Institute of Environmental Health Sciences paper(1) is sounding the alarm about detectable per- and polyfluoroalkyl substances (PFAS) in blood samples of Delaware residents.

It sounds scary, but scientifically there are two things to keep in mind:

1. We can detect anything in anything in 2025.
2. Presence is not pathology.

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Having interacted for a few months with ChatGPT 5 now, both for work-related problems and for private / self-learning tasks, I feel I might share some thoughts here on what these large models can tell us about our own thought processes. 

The sentence above is basically giving away my bottomline from square one, but I suppose I can elaborate a bit more on the concept. LLMs have revolutionized a wide range of information-processing tasks in just three or four years. Looking back, the only comparable breakthrough I can recall is the advent of internet search engines in the early 1990s. But as exciting and awesome this breakthrough is, it inspires me still more to ponder on how this is even possible. Let me unpack this.

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A new study describes a new liquid phase in thin films of a glass-forming molecules. These results demonstrate how these glasses and other similar materials can be fabricated to be denser and more stable, providing a framework for developing new applications and devices through better design.

New research has identified potential treatment that could improve the human immune system's ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate the immune system, which in turn can unleash other immune cells to attack tumours in cancer patients.

University of Washington scientists have developed a statistical framework that incorporates key COVID-19 data -- such as case counts and deaths due to COVID-19 -- to model the true prevalence of this disease in the United States and individual states. Their approach projects that in the U.S. as many as 60% of COVID-19 cases went undetected as of March 7, 2021, the last date for which the dataset they employed is available.

Mice exposed to the opioid oxycodone before birth experience permanent changes in behavior and gene expression. The new research published in eNeuro highlights a need to develop safer types of painkillers for pregnant women.

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum. These findings are reported in Recent ultra-rare inherited variants implicate new autism candidate risk genes, a new study published in Nature Genetics.

An international team of researchers from the Max Planck Institute for Plant Breeding Research and the University of Åarhus in Denmark have discovered that bacteria from the plant microbiota are adapted to their host species. In a newly published study, they show how root-associated bacteria have a competitive advantage when colonizing their native host, which allows them to invade an already established microbiota.

A new study reports that among individuals who had an allergic reaction to their first mRNA COVID-19 vaccine dose, all who went on to receive a second dose tolerated it. Even some who experienced anaphylaxis following the first dose tolerated the second dose.

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.

What The Study Did: Survey data were used to investigate the relationship between loneliness and high-risk medication use in adults older than age 65.

What The Study Did: The association between Medicare eligibility at age 65 and changes in racial and ethnic disparities in access to care and self-reported health was evaluated in this study.

What The Study Did: Researchers examined the safety of the second dose of the Pfizer-BioNTech or Moderna COVID-19 vaccines in patients who experienced an allergic reaction to the first dose.

The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can't recognize that without guidance from the hippocampus, according to a new study by neuroscientists at MIT's Picower Institute for Learning and Memory.

Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's Association International Conference® (AAIC®) 2021 in Denver, Colorado, and virtually.