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Water resources: Defusing conflict, promoting cooperation
The EU funded project DAFNE has developed a methodology for avoiding conflicts of use in transboundary rivers. The model-?based procedure allows for participatory planning and cooperative management of water resources. The aim is now for the DAFNE methodology to be implemented in other regions of the world.
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Chemotherapy can induce mutations that lead to pediatric leukemia relapse
A collaboration led by St. Jude Children's Research Hospital, Shanghai Children's Medical Center and others revealed how thiopurines produce mutations that lead to multi-drug resistant leukemia and relapse.
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Topology in biology
A phenomenon known from quantum systems could now make its way into biology:In a new study published in Physical Review X, researchers from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) in Goettingen show that the notion of topological protection can also apply to biochemical networks. The model which the scientists developed makes the topological toolbox, typically used only to describe quantum systems, now also available to biology.
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A new mathematical model assesses ICU patients' mortality risk
Researchers from the Universitat Autònoma de Barcelona (UAB) Department of Mathematics worked in collaboration with the Hospital de Mataró in developing an artificial intelligence-based model for predicting the risk of death of intensive care unit patients according to their characteristics. The model will improve the quality of care in these types of units.
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Study shows environmental link to herbicide-resistant horseweed
Horseweed is a serious threat to both agricultural crops and natural landscapes around the globe. In the U.S., the weed is prolific and able to emerge at any time of the year.
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Brain-repair discovery could lead to new epilepsy treatments
Researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.
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Southeastern US herbaria digitize three million specimens, now freely available online
The National Science Foundation recently provided funding to over 100 herbaria across the Southeast U.S. to digitize more than three million plant specimens collected by botanists and naturalists across the country. Researchers tracked the speed and productivity of staff and students who handled the specimens, from the collection drawers to online repositories, to provide institutions with a framework to better determine the time and money needed to digitize remaining collections.
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Shedding light on the dark side of firm lobbying
A firm's focus on customers may be diminished when it lobbies. Firm focus can be reoriented to customers, but doing so requires intentional, marketing-focused efforts.
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Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are activated by RA-induced Fgr expression
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Making negative opinions agreeable: Study finds social sharing happens in terms of support
Despite how toxic the social media sandbox can get, people more often share attitudes that are framed in terms of support instead of opposition, according to new research.
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Sharks, lies, and videotape: Scientists document problems with shark week
A new analysis by scientists shows that Shark Week, now in its 33rd year on the Discovery Channel, is deeply flawed in ways that undermine its goals, potentially harming both sharks and shark scientists. To document just how pervasive these issues are, a team of researchers performed a content and discourse analysis of more than 200 Shark Week episodes.
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"Noisy" gene expression may help improve stem cell therapies
As reported in the journal Science, Leor Weinberger and his team at Gladstone Institutes have discovered a pathway they named discordant transcription through repair (DiThR, pronounced "dither"). The DiThR pathway appears to boost the noisiness of gene expression in stem cells and enhance their ability to differentiate.
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Martian global dust storm ended winter early in the south
A dust storm that engulfed Mars in 2018 destroyed a vortex of cold air around the planet's south pole and brought an early spring to the hemisphere. By contrast, the storm caused only minor distortions to the polar vortex in the northern hemisphere and no dramatic seasonal changes.
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New dietary treatment for epilepsy well tolerated and reduced seizures
The first clinical trial of a new dietary treatment for children and adults with severe forms of epilepsy, co-developed by UCL researchers and based on the ketogenic diet, has been successfully completed.
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Meet the Martian meteorite hunters
A team at the Natural History Museum (NHM), London is paving the way for future rovers to search for meteorites on Mars. The scientists are using the NHM's extensive meteorite collection to test the spectral instruments destined for the ExoMars rover Rosalind Franklin, and develop tools to identify meteorites on the surface of the red planet. The project is being presented today (23 July) at the virtual National Astronomy Meeting 2021.
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Studies find combination chemotherapy beneficial and cost-effective in sub-Saharan Africa
Researchers at the UNC Lineberger Comprehensive Cancer Center demonstrated in a clinical trial in Malawi that a five-drug combination chemotherapy provided curative benefit compared to current standard-of care-therapy in people diagnosed with lymphoma, and now they have determined this option is also cost-effective.
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Mayo Clinic research suggests women over 65 be offered hereditary cancer genetic testing
A new study by Fergus Couch, Ph.D., of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology.
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Advanced bladder cancers respond to immunotherapy regardless of gene mutation status
UNC Lineberger researchers and colleagues report a study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy in a manner that is similar to patients without that mutation. This discovery runs counter to previous research that suggested FGFR3-mutated bladder cancers should not be treated with immunotherapy.
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Doctoral student bridges gap between electronics and optics
According to the United Nations' telecommunications agency, 93% of the global population has access to a mobile-broadband network of some kind. With data becoming more readily available to consumers, there is also an appetite for more of it, and at faster speeds.
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New tests can detect tiny but toxic particles of coal ash in soil
Duke University scientists have developed tests sensitive enough to detect and measure microscopic particles of coal ash in soil, even at concentrations so low and sizes so small that other tests would likely miss them. The four new tests complement tests previously developed at Duke to detect coal ash contamination in water and larger particles of coal ash in soil.
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