Research into the self-destruction of cells in humans and plants could lead to treatments for neurodegenerative brain diseases and the development of disease-resistant plants.
A study co-led by The University of Queensland's Professor Bostjan Kobe identified the role certain proteins play in cellular suicide.
"To sustain life, diverse organisms like humans and plants have cells that commit suicide for the benefit of the rest of the organism," Professor Kobe said.
Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia.
Globally, it is estimated that nearly two billion people suffer from zinc deficiency, but why this increases susceptibility to bacterial infection has not been well understood - until now.
In the first continent-wide genomic study of malaria parasites in Africa, scientists have uncovered the genetic features of Plasmodium falciparum parasites that inhabit different regions of the continent, including the genetic factors that confer resistance to anti-malarial drugs. This sheds new light on the way that drug resistance is emerging in different locations and moving by various routes across Africa, putting previous success in controlling malaria at risk.
The first detailed map of individual malaria parasite behaviour across each stage of its complicated life cycle has been created by scientists. Researchers at the Wellcome Sanger Institute and their collaborators used advanced single-cell technology to isolate individual parasites and measure their gene activity. The result is the Malaria Cell Atlas, which gives the highest resolution view of malaria parasite gene expression to date and monitors how individual parasites change as they develop in both the mosquito and human host.
Cells rely on protein complexes known as ATP synthases or ATPases for their energy needs - adenosine triphosphate (ATP) molecules power most of the processes sustaining life. Structural biologist Professor Leonid Sazanov and his research group from the Institute of Science and Technology Austria (IST Austria) in Klosterneuburg, Austria have now determined the first atomic structure of the representative of the V/A-ATPase family, filling in the gap in the evolutionary tree of these essential molecular machines.
When it comes to climate change, moving people and development away from at-risk areas can be viewed, not as a defeat, but as a smart strategy that allows communities to adapt and thrive.
That's the case for carefully planned "managed retreat" made by three environmental researchers in an article published Aug. 22 in the Policy Forum section of the journal Science. The article was written by lead author A.R. Siders of the University of Delaware, with co-authors Miyuki Hino and Katharine J. Mach of Stanford University and the University of Miami.
(BOSTON) -- The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide position of the vast reaches of the genome. It is also being harnessed in ongoing diagnostic approaches for the detection of pathogens and disease-causing mutations in patients.
Storm clouds rooted deep in Jupiter's atmosphere are affecting the planet's white zones and colorful belts, creating disturbances in their flow and even changing their color.
Thanks to coordinated observations of the planet in January 2017 by six ground-based optical and radio telescopes and NASA's Hubble Space Telescope, a University of California, Berkeley, astronomer and her colleagues have been able to track the effects of these storms -- visible as bright plumes above the planet's ammonia ice clouds -- on the belts in which they appear.
Worcester, Mass. - Aug. 22, 2019 - By combining cutting-edge machine learning with 19th-century mathematics, a Worcester Polytechnic Institute (WPI) mathematician is working to make NASA spacecraft lighter and more damage tolerant by developing methods to detect imperfections in carbon nanomaterials used to make composite rocket fuel tanks and other spacecraft structures.
HOUSTON - (Aug. 22, 2019) - How do you know a cell has a fever? Take its temperature.
That's now possible thanks to research by Rice University scientists who used the light-emitting properties of particular molecules to create a fluorescent nano-thermometer.
The Rice lab of chemist Angel Martí revealed the technique in a Journal of Physical Chemistry B paper, describing how it modified a biocompatible molecular rotor known as boron dipyrromethene (BODIPY, for short) to reveal temperatures inside single cells.
A 100-year flood is supposed to be just that: a flood that occurs once every 100 years, or a flood that has a one-percent chance of happening every year.
But Princeton researchers have developed new maps that predict coastal flooding for every county on the Eastern and Gulf Coasts and find 100-year floods could become annual occurrences in New England; and happen every one to 30 years along the southeast Atlantic and Gulf of Mexico shorelines.
PHOENIX, Ariz. -- Aug. 22, 2019 -- An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.
The study results, published today in Nature Communications, suggest that scientists have identified a unique way to disrupt the cellular process that contributes to Diffuse Intrinsic Pontine Gliomas (DIPG).
Ew, a cockroach! But it zips off before the swatter appears. Now, researchers have leveraged the bug's superb scurrying skills to create a cleverly simple method to assess and improve locomotion in robots.
Cells can be viewed as natural minicomputers that execute programs encoded in their DNA. In a paper appearing August 22 in the journal Molecular Cell, MIT researchers describe a new technology that uses DNA for information processing and storage in living cells.