PHILADELPHIA--Doctors diagnose about 2000 adults with uveal melanoma, a cancer of the eye, every year. In half of cases, the disease metastasizes to the liver. For these patients treatment options are scarce. Researchers at the Sidney Kimmel Cancer Center (SKCC) -- Jefferson Health and the Icahn School of Medicine at Mt.

BEER-SHEVA, Israel...January 4, 2019 - Ben-Gurion University researchers have developed a new satellite imaging system that could revolutionize the economics and imagery available from space-based cameras and even earth-based telescopes.

"This is an invention that completely changes the costs of space exploration, astronomy, aerial photography, and more," says Angika Bulbul, a BGU Ph.D. candidate under the supervision of Prof. Joseph Rosen in the BGU Department of Electrical and Computer Engineering.

Researchers at MIT and Arizona State University have designed a computer program that allows users to translate any free-form drawing into a two-dimensional, nanoscale structure made of DNA.

Until now, designing such structures has required technical expertise that puts the process out of reach of most people. Using the new program, anyone can create a DNA nanostructure of any shape, for applications in cell biology, photonics, and quantum sensing and computing, among many others.

ALBUQUERQUE, N.M. -- When people are in the early stages of an undiagnosed disease, immediate tests that lead to treatment are the best first steps. But a blood draw -- usually performed by a medical professional armed with an uncomfortably large needle -- might not be quickest, least painful or most effective method, according to new research.

UPTON, NY--This holiday season, scientists at the Center for Functional Nanomaterials (CFN)--a U.S. Department of Energy Office of Science User Facility at Brookhaven National Laboratory--have wrapped a box of a different kind. Using a one-step chemical synthesis method, they engineered hollow metallic nanosized boxes with cube-shaped pores at the corners and demonstrated how these "nanowrappers" can be used to carry and release DNA-coated nanoparticles in a controlled way. The research is reported in a paper published on Dec.

University of Arizona biomedical engineering professor Philipp Gutruf is first author on the paper Fully implantable, optoelectronic systems for battery-free, multimodal operation in neuroscience research, published in Nature Electronics.

A major Cardiovascular (CV) risk factor is low-density Lipoprotein Cholesterol (LDL-C). A lot of evidence that was accumulated supports a linear association between LDL-C levels and CV risk. However, whether the lower limit of LDL-C might offer CV benefits without any safety concerns is still a topic of debate.

This review discusses data from studies of several safety events that have been associated with low LDL-C levels achieved with major lipid-lowering drug.

Familial hypercholesterolemia is a hereditary genetic disorder predisposing in premature atherosclerosis and cardiovascular complications. Early diagnoses as well as effective treatment strategies in affected children are challenges among experts. Universal screening and cascade screening among families with familial hypercholesterolemia are being controversially discussed.

Research suggests a specific treatment for Homozygous Familial Hypercholesterolaemic (HoFH) pateints; a combination therapy with PCSK9-inhibitors (PCSK9-I) and lipoprotein-apheresis (LA) may have synergistic effects on circulating lipid and lipoprotein levels. The relationship with the treatment regimen mentioned above can be investigated further with larger datasets.

1. Canagliflozin not associated with increased risk for fracture
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