Tech

US study confirms effectiveness of quadrivalent human papillomavirus (HPV) vaccine in women aged up to 20 years who receive all three doses, but more research is needed in women aged 21-26 years.

For women aged 14-20 years, catch-up HPV vaccination - offered if American women miss the recommended vaccination series at 11-12 years - is effective against the risk of important cervical precancers if women receive all three doses, according to a population case-control study of over 25000 people published in The Lancet Child & Adolescent Health journal.

Researchers from ITMO University developed and tested an MRI coil providing high-resolution imaging of the whole body of a mouse. Such coils are used in preclinical testing, as well as in imaging of various body systems. The new coil produces images with three times higher resolution than standard commercial volume MRI coils. Scientist used inexpensive materials and manufacturing technology that may be adjusted for various research projects. The research was published in NMR in Biomedicine as the cover story.

HOUSTON - (Aug. 6, 2018) - Rice University scientists are developing technology to remove contaminants from water - but only as many as necessary.

The Rice lab of engineer Qilin Li is building a treatment system that can be tuned to selectively pull toxins from drinking water and wastewater from factories, sewage systems and oil and gas wells. The researchers said their technology will cut costs and save energy compared to conventional systems.

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine. In the case of therapeutics, the 3D shape of a molecule can be critical to activity.

Monday, July 6, 2018 - Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

Transplantation followed by antiviral therapy cured hepatitis C in 100 percent of patients receiving kidneys from infected donors

Abstract: http://annals.org/aim/article/doi/10.7326/M18-0749
Editorial: http://annals.org/aim/article/doi/10.7326/M18-1781
URLs go live when the embargo lifts

Bottom Line: Postmenopausal bleeding is a common symptom among most women with endometrial cancer but most women with postmenopausal bleeding won't be diagnosed with endometrial cancer, findings that raise questions about how to best manage postmenopausal bleeding for the early detection of endometrial cancer.

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.

Results of the international study published on August 6 in JAMA Pediatrics.

Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor (BDNF) was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators at the Medical University of South Carolina (MUSC) in an article published online in June 2018 by Addiction Biology. "We discovered that a very common protein in the brain has an additional significant role in addiction relapse," says lead author Ana-Clara Bobadilla, Ph.D., a postdoctoral scholar in the laboratory of Peter Kalivas, Ph.D., at MUSC.

HOUSTON - (Aug. 3, 2018) - Rice University researchers have found that fracture-resistant "rebar graphene" is more than twice as tough as pristine graphene.

Graphene is a one-atom-thick sheet of carbon. On the two-dimensional scale, the material is stronger than steel, but because graphene is so thin, it is still subject to ripping and tearing.