Genomes are catalogs of hereditary information that determine whether an organism becomes a plant, animal, fungus or microbe, and whether the organism is adapted to its surroundings. Determining the sequence of DNA within genomes is crucial to human medicine, crop genetics, biotechnology, forensic science, threatened species management, and evolutionary studies. The last 5 years have witnessed tremendous advances in DNA sequencing technologies, and it is now possible to sequence millions of fragments of DNA in a single analysis, and at a fraction of their previous cost.