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SFU researchers help discover new HIV vaccine-related tool

A new discovery involving two Simon Fraser University scientists could lead to a little known and benign bacterium becoming a vital new tool in the development of a vaccine against human immunodeficiency virus (HIV).

Ralph Pantophlet, a Faculty of Health Sciences assistant professor, and Kate Auyeung, his senior research assistant and lab manager at SFU, and scientists in Italy have made a breakthrough discovery about Rhizobium radiobacter.

The journal Chemistry & Biology has just published their research in its Feb. 24 issue.

T. Rex's killer smile revealed

Edmonton -- One of the most prominent features of life-size, museum models of Tyrannosaurus rex, is its fearsome array of flesh-ripping, bone-crushing teeth.

Until recently most researchers only noted the varying size of T. rex's teeth when they studied the carnivore's smile.

But now a University of Alberta paleontologist has discovered that beyond the obvious difference in size of each tooth family, there is considerable variation in the serrated edges of the teeth.

Family tree may clarify death risk for inherited heart rhythm disorders

Reconstructing family trees dating back to 1811, Dutch researchers have estimated the death risk for people with inherited heart rhythm disorders, according to a study in Circulation: Cardiovascular Genetics, a journal of the American Heart Association.

Heart rhythm disorders can result in sudden cardiac death in apparently healthy people because of severe disturbances in the rhythm of the heart. The risk is high for people who carry one of these rare genes and have symptoms such as fainting.

Researchers find potential solution to melanoma's resistance to vemurafenib

TAMPA, Fla. -- Researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues in California have found that the XL888 inhibitor can prevent resistance to the chemotherapy drug vemurafenib, commonly used for treating patients with melanoma.

Notre Dame researchers are providing insights into elephant behavior and conservation issues

Last year, Kenya lost 278 elephants to poachers, as compared to 177 in 2010. On the continent of Africa as whole, elephants have declined from an estimated 700,000 in 1990 to 360,000 today due to the demands of the ivory trade.

Spend some time with University of Notre Dame researchers Elizabeth Archie and Patrick Chiyo and you'll gain a better understanding of just what a tragic loss elephant poaching is.

A thinking, reasoning species with extraordinary memories, a strong sense of families and caring and nurturing natures are increasingly at the risk of extinction.

Stopping hormones might help breast cancer to regress

SEATTLE—As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention.

As part of the national Breast Cancer Surveillance Consortium, researchers studied 741,681 woman-years of data (with a median of 3.3 years per woman) on 163,490 women aged 50-79 who were Group Health Cooperative members and had no prior history of breast cancer.

Iowa State, Ames Lab chemists aid study of mutated plants that may be better for biofuels

AMES, Iowa – Genetic mutations to cellulose in plants could improve the conversion of cellulosic biomass into biofuels, according to a research team that included two Iowa State University chemists.

Another mechanism discovered by which sulforaphane prevents cancer

CORVALLIS, Ore. – Researchers in the Linus Pauling Institute at Oregon State University have discovered yet another reason why the "sulforaphane" compound in broccoli and other cruciferous vegetables is so good for you – it provides not just one, but two ways to prevent cancer through the complex mechanism of epigenetics.

UBC researcher invents 'lab on a chip' device to study malaria

University of British Columbia researcher Hongshen Ma has developed a simple and accurate device to study malaria, a disease that currently affects 500 million people per year worldwide and claims a million lives.

Spread by mosquitoes, malaria is caused by a tiny parasite that infects human red blood cells. Ma and his team designed a "lab on a chip" device to better understand the changes in red blood cells caused by Plasmodium falciparum, the most common species of malaria parasites.

Predicting children's language development

Montreal, February 28, 2012 - We depend on a barrage of standardized tests to assess everything from aptitude to intelligence. But do they provide an accurate forecast when it comes to something as complex as language? A study by Diane Pesco, an assistant professor in Concordia's Department of Education, and co-author Daniela O'Neill, published earlier this year in the Journal of Speech, Language, and Hearing Research, shows that the Language Use Inventory (LUI) does.

Cold air chills heart's oxygen supply

People with heart disease may not be able to compensate for their bodies' higher demand for oxygen when inhaling cold air, according to Penn State researchers, making snow shoveling and other activities dangerous for some.

"This study can help us understand why cold air is such a trigger for coronary events," said Lawrence I. Sinoway, Distinguished Professor of Medicine and director of the Heart and Vascular Institute, Penn State College of Medicine.

Scientists discover new 'off switch' in immune response

Scientists from Trinity College Dublin have discovered a new 'off switch' in our immune response which could be boosted in diseases caused by over-activation of our immune system, or blocked to improve vaccines. The findings are published this week in the journal Nature Communications. The research was funded by Health Research Board, Ireland and Science Foundation Ireland.

NIH-supported scientists investigate a newly emerging staph strain

Using genome sequencing and household surveillance, National Institutes of Health (NIH) scientists and their colleagues from Columbia University Medical Center and St. George's University of London have pieced together how a newly emerging type of Staphylococcus aureus bacteria has adapted to transmit more easily among humans. Their new study underscores the need for vigilance in surveillance of S. aureus.

Health counseling in doctors' office reduces obesity more effectively than doctor's advice

A physical activity and diet program implemented by health educators working in a doctor's office may be a more effective way to get obese people to lose abdominal fat than advice from a doctor alone, according to a study from Queen's University.

Most primary care physicians do not have the time to provide high-intensity behavioral counseling to their patients, says the report by Robert Ross, a professor from the School of Kinesiology and Health Studies.

Women decrease condom use during freshman year of college, study finds

PROVIDENCE, R.I. – Women gradually use condoms less frequently during their first year of college, according to a new study by researchers from The Miriam Hospital's Centers for Behavioral and Preventive Medicine. This was particularly true for women who binge drink, have lower grade point averages or come from lower socioeconomic backgrounds.

The findings, published online in the Journal of Sex Research, offer some of the first clues to how condom use changes during the college years – a time when young people are sexually active and use condoms inconsistently.