Body

In the genes, but which ones?

For decades, scientists have understood that there is a genetic component to intelligence, but a new Harvard study has found both that most of the genes thought to be linked to intelligence are probably not in fact related to it, and identifying intelligence's specific genetic roots may still be a long way off.

A biodiversity discovery that was waiting in the wings -- wasp wings, that is

From spaghetti-like sea anemones to blobby jellyfish to filigreed oak trees, each species in nature is characterized by a unique size and shape. But the evolutionary changes that produce the seemingly limitless diversity of shapes and sizes of organisms on Earth largely remains a mystery. Nevertheless, a better understanding of how cells grow and enable organisms to assume their characteristic sizes and shapes could shed light on diseases that involve cell growth, including cancer and diabetes.

Combined inhibition of VEGF and c-MET can decrease metastasis

  • Inhibition of VEGF increased c-MET expression in tumors.
  • Invasion and metastasis were blocked by inhibition of VEGF plus c-MET.
  • Dual VEGF/c-MET inhibitors are in late-stage clinical trials.

PHILADELPHIA — Dual inhibition of vascular endothelial growth factor and c-MET signaling inhibited tumor invasion and metastasis in a laboratory model of pancreatic neuroendocrine cancer, according to a paper published in Cancer Discovery, the newest journal of the American Association for Cancer Research.

Cancer therapy more potent when it hits 2 targets

Simultaneous targeting of two different molecules in cancer is an effective way to shrink tumors, block invasion, and stop metastasis, scientists at the University of California, San Francisco (UCSF) have found—work that may improve the effectiveness of combination treatments that include drugs like Avastin.

A new radiotherapy technique significantly reduces irradiation of healthy tissue

Researchers at the University of Granada and the university hospital Virgen de las Nieves in Granada have developed a new radiotherapy technique that is much less toxic than that traditionally used and only targets cancerous tissue.

This new protocol provides a less invasive but equally efficient cancer postoperative treatment for cases of cancer of the oral cavity and pharynx.

Protecting the climate by reducing fluorinated greenhouse gas emissions

Hydrofluorocarbons (HFCs), which have been used in recent years in increasing quantities as substitutes for CFCs, are also climatically very active and many are also extremely long-lived. In the renowned journal Science an international team of researchers recommends that the most potent of these gases also be regulated. This could save the positive «side effect» of the Montreal Protocol for the global climate.

A study describes liquid water diffusion at molecular level

An article published in Physical Review and conducted by researchers at the universities of Granada and Barcelona might lead to a revolutionary change in water desalination and filtration methods.

92 percent of families with adopted children are satisfied with their decision

Two separate surveys six years apart have been used to analyse the level of satisfaction with adoptions in Andalucía. The study shows that 77.7% of families are happier after the process and variables that make it more difficult have been identified, such as the age of the children when arriving, multiple adoption and previous experiences of abuse. There is a significant link between the parents' assessment and that of the children.

Novel bioactive peptides promote wound healing in vivo

BOSTON (February 23, 2012, 5:00 pm ET) — Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds.

New theory shows that neither birth nor death stops a flock

EUGENE, Ore. -- (Feb. 24, 2011) -- Neither births nor deaths stop the flocking of organisms. They just keep moving, says theoretical physicist John J. Toner of the University of Oregon. The notion, he says, has implications in biology and eventually could point to new cancer therapies.

Characteristics of fathers with depressive symptoms

New York City, February 23, 2012 – Voluminous research literature attests to the multiple negative consequences of maternal depression and depressive symptoms for the health and development of children. In contrast, there is a profound paucity of information about depressive symptoms in fathers according to a follow up study by NYU School of Medicine researchers in the February 23rd online edition of Maternal and Child Health Journal.

Natural method for clearing cellular debris provides new targets for lupus treatment

Augusta, Ga. – Cells that die naturally generate a lot of internal debris that can trigger the immune system to attack the body, leading to diseases such as lupus.

Now Georgia Health Sciences University researchers report that an enzyme known to help keep a woman's immune system from attacking a fetus also helps block development of these autoimmune diseases that target healthy tissues, such as DNA or joints.

Cunning super-parasitic wasps sniff out protected aphids and overwhelm their defenses

In the war between parasite and host, the parasitic wasp, Aphidius ervi, and the pea aphid, Acyrthosiphon pisum, are locked in a battle for survival. New research published in BioMed Central's open access journal BMC Biology shows that this cunning parasite sniffs out differences between protected and unprotected aphids, and alters its egg-laying strategy, in order to overwhelm aphid defenses and ensure survival of wasp offspring.

The genetic basis for age-related macular degeneration

Age-related macular degeneration (AMD) is one of the leading causes of blindness worldwide, especially in developed countries, and there is currently no known treatment or cure or for the vast majority of AMD patients. New research published in BioMed Central's open access journal Genome Medicine has identified genes whose expression levels can identify people with AMD, as well as tell apart AMD subtypes.

Genetic variants affect arsenic metabolism and toxicity in Bangladesh

A large-scale genomic study conducted in Bangladesh has discovered genetic variants that control arsenic metabolism and elevate the risk of skin lesions in people chronically exposed to arsenic. In PLoS Genetics, researchers from the University of Chicago, Columbia University, the International Center for Diarrheal Disease Research in Bangladesh, and the University of North Carolina report that genetic variants found near the enzyme for metabolizing the chemical into a less toxic form are associated with an individual's risk of developing arsenic-related disease.