Body

Of bio-hairpins and polymer-spaghetti

Jülich, Germany, 9 October 2014 – When a basically sturdy material becomes soft and spongy, one usually suspects that it has been damaged in some way. But this is not always the case, especially when it comes to complex fluids and biological cells.

Human health, wealth require expanded marine science, experts say

Some 340 European scientists, policy-makers and other experts representing 143 organizations from 31 countries spoke with one voice today, publishing a common vision of today's most pressing marine-related health and economic threats and opportunities.

In a declaration concluding a three day meeting in Rome, EurOcean 2014 participants also released an agreed, five-year roadmap to achieve expanded, more integrated and effective policy-oriented ocean scrutiny.

Why men are the weaker sex when it comes to bone health

Nyon, Switzerland (October 9, 2014) – Alarming new data published today by the International Osteoporosis Foundation (IOF), shows that one-third of all hip fractures worldwide occur in men, with mortality rates as high as 37% in the first year following fracture. This makes men twice as likely as women to die after a hip fracture. Osteoporosis experts warn that as men often remain undiagnosed and untreated, millions are left vulnerable to early death and disability, irrespective of fracture type.

Circulating tumor cells provide genomic snapshot of breast cancer

(PHILADELPHIA) -- The genetic fingerprint of a metastatic cancer is constantly changing, which means that the therapy that may have stopped a patient's cancer growth today, won't necessarily work tomorrow. Although doctors can continue to biopsy the cancer during the course of the treatment and send samples for genomic analysis, not all patients can receive repeat biopsies. Taking biopsies from metastatic cancer patients is an invasive procedure that it is frequently impossible due to the lack of accessible lesions.

Women who eat fried food regularly before conceiving are at increased risk of developing gestational diabetes during pregnancy

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that women who eat fried food regularly before conceiving are at increased risk of developing gestational diabetes during pregnancy. The research is led by Drs Cuilin Zhang and Wei Bao, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, part of the US National Institutes of Health) Rockville, MD, USA, and colleagues.

New gene therapy for 'bubble boy' disease appears effective, safe, study in NEJM reports

BOSTON (October 9, 2014) –A new form of gene therapy for boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a life-threatening condition also known as "bubble boy" disease, appears to be both effective and safe, according to a collaborative research team from Dana-Farber/Boston Children's Cancer and Blood Disorders Center and other institutions conducting an international clinical trial. Early data suggest that the therapy may avoid the late-developing leukemia seen in a quarter of SCID-X1 patients in pioneering gene therapy trials in Europe more than a decade ago.

Novel protein in heart muscle linked to cardiac short-circuiting and sudden cardiac deaths

NEW YORK, NY – Cardiovascular scientists at NYU Langone Medical Center have identified in mouse models a protein known as Pcp4 as a regulator of the heart's rhythm. Additionally, when the Pcp4 gene is disrupted, it can cause ventricular arrhythmias.

Results from this animal study were released online Oct. 8 in the peer-reviewed publication, The Journal of Clinical Investigation.

Patient's dramatic response and resistance to cancer drug traced to unsuspected mutations

BOSTON – The DNA of a woman whose lethal thyroid cancer unexpectedly "melted away" for 18 months has revealed new mechanisms of cancer response and resistance to the drug everolimus, said researchers from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Gene therapy shows promise for severe combined immunodeficiency

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Skin exposure may contribute to early risk for food allergies

(NEW YORK – October 08, 2014) Many children may become allergic to peanuts before they first eat them, and skin exposure may be contribute to early sensitization, according to a study in mice led by Mount Sinai researchers and published today in the Journal of Clinical Investigation. Early in the process of developing an allergy, skin exposure to food allergens contributes to "sensitization", which means the skin is reactive to an antigen, such as peanuts, especially by repeated exposure.

More appropriate use of cardiac stress testing with imaging could reduce health costs

New York City – October 8, 2014 – In a new study recently published in the Annals of Internal Medicine, researchers at NYU Langone Medical Center concluded that overuse of cardiac stress testing with imaging has led to rising healthcare costs and unnecessary radiation exposure to patients.

Study finds early signs of heart trouble in obese youth

WASHINGTON (Oct. 8, 2014) — A study that used two-dimensional echocardiography to closely examine the hearts of 100 children and teens found physical and functional signs of future heart problems already developing in obese children.

Zoos exonerated in baby elephant deaths; Data support new branch of herpesvirus family

WASHINGTON, DC – October 8, 2014 - Elephants are among the most intelligent non-humans, arguably on par with chimps, but both African and Asian elephants—separate species—are endangered. In 1995, 16-month old Kumari, the first Asian elephant born at the National Zoo in Washington, DC, died of a then-mysterious illness. In 1999, Gary Hayward of Johns Hopkins University and collaborators published their results identifying a novel herpesvirus, EEHV1 as the cause of Kumari's sudden death.

Plant scientist discovers basis of evolution in violins

ST. LOUIS, MO – OCTOBER 8, 2014 – What could the natural diversity and beauty of plant leaves have in common with one of mankind's greatest creative inventions, the violin? Much more than you might imagine.

What's your status?

In western society, where keeping up with the Joneses — or, better yet, surpassing them — is expected and even encouraged, status matters. So important is it that for many people, physical and emotional wellbeing are directly connected to their place in the social hierarchy.