Body

Treating C. diff infection with oral, frozen encapsulated fecal material

A preliminary study has shown the potential of treating recurrent Clostridium difficile infection (a bacterium that is one of the most common causes of infection of the colon) with oral administration of frozen encapsulated fecal material from unrelated donors, which resulted in an overall rate of resolution of diarrhea of 90 percent, according to a study published in JAMA. The study is being released early online to coincide with its presentation at IDWeek 2014.

Body contouring after bariatric surgery helps obese patients keep the weight off

DETROIT – Patients who have plastic surgery to reshape their bodies after bariatric procedures are able to maintain "significantly greater" weight loss than those who do not have surgery, according to a new study by Henry Ford Hospital researchers.

"As plastic and reconstructive surgeons, we are encouraged by the idea that improved body image can translate into better long-term maintenance of a healthier weight, and possibly a better quality of life for our patients," says Donna Tepper, M.D., a Henry Ford plastic surgeon and senior author of the study.

Special chromosomal structures control key genes

Within almost every human cell is a nucleus six microns in diameter—about one 300th of a human hair's width—that is filled with roughly three meters of DNA. As the instructions for all cell processes, the DNA must be accessible to the cell's transcription machinery yet be compressed tightly enough to fit inside the nucleus. Scientists have long theorized that the way DNA is packaged affects gene expression. Whitehead Institute researchers present the first evidence that DNA scaffolding is responsible for enhancing and repressing gene expression.

New cough study demonstrates diphenhydramine to inhibit cough reflex with Dr. Cocoa form

SAN DIEGO, CA, October 11, 2014 – Cough is among the most common complaints for which patients seek medical attention. Leading cough researcher Peter V. Dicpinigaitis, M.D., Professor of Clinical Medicine at New York's Albert Einstein College of Medicine, recently conducted a new cough challenge study among adults, whose results were first presented at the European Respiratory Society International Congress in September 2014.

Cellular 'power grid' failure triggers abnormal heart rhythms after a heart attack

Heart attack survivors often experience dangerous heart rhythm disturbances during treatment designed to restore blood flow to the injured heart muscle, a common and confounding complication of an otherwise lifesaving intervention.

Thank fruit flies for that pleasing beer scent

The familiar smell of beer is due in part to aroma compounds produced by common brewer's yeast. Now, researchers reporting in the Cell Press journal Cell Reports on October 9th have discovered why the yeast (formally known as S. cerevisiae) make that smell: the scent attracts fruit flies, which repay the yeast by dispersing their cells in the environment.

Yeast lacking a single aroma gene fail to produce their characteristic odor, and they don't attract fruit flies either.

TSRI scientists create mimic of 'good' cholesterol to fight heart disease and stroke

LA JOLLA, CA – October 9, 2013 - Scientists at The Scripps Research Institute (TSRI) have created a synthetic molecule that mimics "good" cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks.

This research, published in the October issue of Journal of Lipid Research, points scientists toward a new method for treating atherosclerosis, a condition where plaque buildup in the arteries can cause heart attacks and strokes.

Researchers find RNA molecules in urine and tissue that detect prostate cancer

Philadelphia, PA, October 9, 2014 – Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals. The study sets the stage for the development of more sensitive and specific noninvasive tests for prostate cancer than those currently available, which could result in fewer unnecessary prostate biopsies with less treatment-related morbidity, according to a new study in The Journal of Molecular Diagnostics.

Hidden population: Thousands of youths take on caregiver role at home

SAN DIEGO – While the typical preteen or adolescent can be found playing sports or video games after school, more than 1.3 million spend their free time caring for a family member who suffers from a physical or mental illness, or substance misuse.

Research shows incorrect use of car seats widespread on first trip home from hospital

SAN DIEGO – Nearly all parents unknowingly put their newborn infants at risk as soon as they drive away from the hospital due to mistakes made with car safety seats, according to research to be presented Monday, Oct. 13 at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.

Computerized surveillance system quickly detects disease outbreaks among preschoolers

SAN DIEGO – A web-based system that allows preschools and child care centers to report illnesses to local public health departments could improve the detection of disease outbreaks and allow resources to be mobilized more quickly, according to research to be presented Saturday, Oct. 11 at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.

Counting pitches can save young players' arms but not always used consistently

SAN DIEGO – Youth baseball has morphed into a year-round sport, with some athletes playing on multiple teams in the same season. One result: an increasing number of pitchers sidelined with overuse injuries or needing surgery.

Guidelines on how many pitches young athletes should throw have been developed to stem the tide of injuries, but many coaches are not following the recommendations consistently, according to a study to be presented at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.

Survey: Moms who choose to breastfeed older babies motivated by health, nutrition benefits

SAN DIEGO – Mothers who decide to breastfeed their children beyond 1 year of age consider their child's physical and social development to be most important, while the advice of health care professionals, family and friends are least important, according to a study to be presented Monday, Oct. 13 at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.

To find out why some moms choose to continue nursing after a child's first birthday, researchers surveyed more than 50,000 U.S. women ages 18-50.

Research to be presented by high school students at AAP conference reveals that some adolescents adept at media multitasking

SAN DIEGO – Telling youths who are juggling multiple electronic devices to "focus on the task at hand" may not always be good advice, according to research to be presented by two high school students on Saturday, Oct. 11 at the American Academy of Pediatrics (AAP) National Conference & Exhibition.

Study: Splints placed improperly in 93 percent of suspected pediatric fractures

SAN DIEGO – October 10, 2014. More than 90 percent of potential pediatric fractures are splinted improperly in emergency rooms and urgent care centers, which can lead to swelling and skin injuries, according to a study by researchers at the University of Maryland School of Medicine. The findings are being presented at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San Diego.