Feed aggregator
Small p values may not yield robust findings: An example using REST-meta-PD
A large number of articles have been published using resting-state functional magnetic resonance imaging for clinical research, and almost all the results survived multiple comparisons correction, a standard procedure performed to reduce false positive rates. Now the researchers from more than 20 worldwide groups have found that in individual studies with small sample sizes, a smaller p value reduced true positive effect and did not save the reproducibility of true effects.
Categories: Content
Coral enhance its environmental adaptability by adjusting trophic status
Under the background of global warming and the increasing impact of human activities, the phenomenon of coral bleaching is becoming more and more serious. Scleractinian coral as mixotrophic organisms, but it is unclear about the impact of trophic flexibility on their environmental adaptability. Recent studies have revealed that coral could enhance its environmental adaptability by adjusting trophic status. This discovery was reported in the cover article of "SCIENCE CHINA: Earth Sciences", Issue 6, 2021.
Categories: Content
Researchers develop world-first weight loss device
University of Otago, New Zealand, and UK researchers have developed a world-first weight-loss device to help fight the global obesity epidemic.
Categories: Content
Study reveals over a £1 million in payments from pharma companies to APPGs
New research published in PLOS One suggests there is a significant lack of transparency in corporate funding to APPGs
Categories: Content
AI learns to predict human behavior from videos
New Columbia Engineering study unveils a computer vision technique for giving machines a more intuitive sense for what will happen next by leveraging higher-level associations between people, animals, and objects."Our algorithm is a step toward machines being able to make better predictions about human behavior, and thus better coordinate their actions with ours," said Computer Science Professor Carl Vondrick. "Our results open a number of possibilities for human-robot collaboration, autonomous vehicles, and assistive technology."
Categories: Content
Males help keep populations genetically healthy
A few males are enough to fertilize all the females. The number of males therefore has little bearing on a population's growth. However, they are important for purging bad mutations from the population. This is shown by a new Uppsala University study providing in-depth knowledge of the possible long-term genetic consequences of sexual selection. The results are published in the scientific journal Evolution Letters.
Categories: Content
Toxicity of protein involved in Alzheimer's triggered by a chemical 'switch'
Tokyo, Japan - Researchers from Tokyo Metropolitan University have discovered that a specific chemical feature of a key protein known as tau may cause it to accumulate in the brain and trigger illnesses like Alzheimer's. They found that disulfide bonds on certain amino acids act to stabilize tau and cause it to accumulate, an effect that got worse with increased oxidative stress. The identification of chemical targets triggering tau accumulation may lead to breakthrough treatments.
Categories: Content
Study shows links between youth distress and stigma around sexual orientation
A new study from American University reveals just how pervasive emotional distress is related to stigma around sexual orientation.
Categories: Content
Market exit: Divestment or redeployment?
A new study published in the Strategic Management Journal (SMJ) examines how the relatedness of businesses and market efficiency might inspire exit through resource redeployment versus divestment.
Categories: Content
Impact of cocoa agroforestry on bird diversity
An estimated 2-3 million hectares of tropical forest were converted to cocoa from 1988-2008 with severe consequences for biodiversity. Unsustainable cocoa monocultures (agricultural systems growing a single crop type) eventually collapse from disease, pests and soil degradation, hurting local communities as well as bird populations. Eliminating monoculture cocoa from supply chains and converting to sustainable agroforestry systems can help maintain productive farms while protecting habitats and biodiversity.
Categories: Content
Elephants solve problems with personality
This study makes connections between two sources of individual variation, personality and cognition, in threatened species.
Categories: Content
Edible Cholera vaccine made of powdered rice proves safe in phase 1 human trials
Vaccine manufacturing made enormous strides in 2020, but the complexity of SARS-CoV-2 vaccines has highlighted the value of inoculations that can be made cheaply and transported and stored without refrigeration. A new needle-free cholera vaccine has been made by grinding up genetically modified grains of rice and can be stored long-term at room temperature. This made-in-Japan innovation has shown no obvious side effects and a good immune response in its Phase 1 clinical trial.
Categories: Content
Differences in human, mouse brain cells have important implications for disease research
A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.
Categories: Content
Unbroken: New soft electronics don't break, even when punctured
A team of Virginia Tech researchers from the Department of Mechanical Engineering and the Macromolecules Innovation Institute has created a new type of soft electronics, paving the way for devices that are self-healing, reconfigurable, and recyclable. These skin-like circuits are soft and stretchy, sustain numerous damage events under load without losing electrical conductivity, and can be recycled to generate new circuits at the end of a product's life.
Categories: Content
Optical tweezer technology tweaked to overcome dangers of heat
Researchers at The University of Texas at Austin have created a new version of optical tweezer technology that fixes a heating problem, a development that could open the already highly regarded tools to new types of research and simplify processes for using them today.
Categories: Content
Backscatter breakthrough runs near-zero-power IoT communicators at 5G speeds everywhere
Researchers at the Georgia Institute of Technology, Nokia Bell Labs, and Heriot-Watt University have found a low-cost way for backscatter radios to support high-throughput communication and 5G-speed Gb/sec data transfer using only a single transistor when previously it required expensive and multiple stacked transistors.
Categories: Content
Mayo Clinic researchers study potential new CAR-T cell therapy for multiple myeloma
Researchers at Mayo Clinic Cancer Center are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment for multiple myeloma. Their findings were published on Friday, June 24, in The Lancet.
Categories: Content
Muscle's smallest building blocks disappear after stroke
Researchers have discovered that, in an attempt to adapt to impairments from stroke, muscles lose sarcomeres -- their smallest, most basic building blocks. The team hopes this discovery can help improve rehabilitation techniques to rebuild sarcomeres, ultimately helping to ease muscle tightening and shortening.
Categories: Content
Loss of circadian regulation allows for increase in glucose production during lung cancer
New research from the University of California, Irvine reveals how the circadian regulation of glucose production in the liver is lost during lung cancer progression, and how the resulting increase in glucose production may fuel cancer cell growth.
Categories: Content
Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
Arizona State University biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment.
Categories: Content