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Previous infection with COVID-19 does not affect the chance of success in IVF

Eurekalert - Jun 28 2021 - 00:06
More than a year after COVID-19 infection rates first hit peak levels and in the knowledge that receptors for SARS-CoV-2 are present in the ovary, are we able to assess the effect of the virus on reproductive function. A new study has shown that the ovarian reserve of women previously infected with the virus was not adversely affected, and that their chance of success from fertility treatment remained as it was before infection.
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AI and computer vision remove the need for cell biopsy in testing embryos

Eurekalert - Jun 28 2021 - 00:06
Testing embryos for aneuploidy (known as PGT-A) has so far required a sample single cell or several cells taken from the embryo by biopsy, and this too has raised fears over safety such that a search for non-invasive methods has arisen in recent years. Now, a new study suggests that euploid embryos can be visually distinguished from aneuploid according to artificial intelligence references of cell activity as seen by time-lapse imaging -- and thus without the need for cell biopsy.
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Researchers engineer cells to destroy malignant tumor cells but leave the rest alone

Eurekalert - Jun 28 2021 - 00:06
Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.
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Trauma patients with COVID-19 face greater risk of complications and death

Eurekalert - Jun 28 2021 - 00:06
COVID-19 complicated patient care in a range of ways, from increased incidence of heart attacks to decreased cancer screenings. The virus also caused a six-fold increase in the risk of complications and death among trauma patients, according to new research.
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Oncotarget: Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

Eurekalert - Jun 28 2021 - 00:06
Support recently reported findings of clinical benefit when relacorilant is added to paclitaxel-containing therapy in patients with ovarian and pancreatic cancers and provide a new rationale for combining relacorilant with additional cytotoxic agents.
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Anti-cancer immunotherapy drug with reduced side effects and increased therapeutic effects

Eurekalert - Jun 28 2021 - 00:06
To tackle this issue, a research team led by Dr. Ju Hee Ryu of the Center for Theragnosis at the Korea Institute of Science and Technology (KIST) has developed an anti-cancer prodrug that can improve anti-cancer immunotherapy by reacting only with cancer cells, thereby minimizing the toxicity to normal cells, including immune cells, and boosting patient immunity.
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Oncotarget: Treatment outcomes in patients with advanced hepatocellular carcinoma

Eurekalert - Jun 28 2021 - 00:06
In CTP class A patients, IGF/CTP score B was associated with shorter PFS and OS
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Oncotarget: Predicting clinical outcomes using cancer progression associated signatures

Eurekalert - Jun 28 2021 - 00:06
The P142 panel of metrics successfully predicted cancer progression status in patients with some, but not all cancer types analyzed.
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Oncotarget: Novel markers of colorectal tumors exhibiting microsatellite instability

Eurekalert - Jun 28 2021 - 00:06
By incorporating cell composition into their regression model, they identified 3,193 differentially expressed genes, of which 556 were deemed novel.
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Heart failure is associated with an increased risk of cancer

Eurekalert - Jun 28 2021 - 00:06
A study in more than 200,000 individuals has found that patients with heart failure are more likely to develop cancer compared to their peers without heart failure. The research is presented today at Heart Failure 2021, an online scientific congress of the European Society of Cardiology (ESC), and published in ESC Heart Failure, a journal of the ESC.
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Escape room simulation promotes infection control adherence at the temple VA

Eurekalert - Jun 28 2021 - 00:06
Designed initially for entertainment purposes, escape rooms are proving their value as medical training tools as demonstrated by the Central Texas Veterans Health Care System. Staff there have used the concept for a flu pandemic escape room and is reporting increased staff handwashing and acceptance of flu vaccines as a result.
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National Poll: 1 in 4 parents worry that their child is behind in developmental milestones

Eurekalert - Jun 28 2021 - 00:06
Nearly a quarter of parents have suspected their child might be delayed in their development, a new national poll finds - but they may not always share these concerns with a doctor.
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Saturated fatty acid levels increase when making memories

Eurekalert - Jun 27 2021 - 00:06
Saturated fatty acid levels unexpectedly rise in the brain during memory formation, according to University of Queensland researchers.
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USTC realizes the first on-chip valley-dependent quantum interference

Eurekalert - Jun 27 2021 - 00:06
USTC realized two-photon quantum interference in the structure of valley-dependent topological insulators based on the valley Hall effect.
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A novel method for controlling the microstructure and performance of 3D printed human implants

Eurekalert - Jun 27 2021 - 00:06
With the rapid development of biomedical technology, the replacement of human skeletal diseases through human implants has become an application market with high technical content and huge benefits. In order to quickly customize human implants with complex structures, Chinese scientists use 3D printing technology to prepare Ti-Mo alloy human implants, and then adjust the microstructure and performance of the human implants through subsequent heat treatment, so as to obtain human implant products with excellent compatibility.
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Researchers perform metabolomic profiling of individual enlarged lysosomes

Eurekalert - Jun 27 2021 - 00:06
The research team from Life Science and Medicine of University of Science and Technology of China, realized lysosome typing based on single lysosome metabonomic information for the first time by stablishing a single lysosome metabonomic mass spectrometry detection technology.
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Virome in marine ecosystems reveal remarkable invertebrate RNA virus diversity

Eurekalert - Jun 27 2021 - 00:06
Oceans viromes remain poorly understood and little is known about the ecological factors driving aquatic RNA virus evolution. In the study, reseaechers used a meta-transcriptomics approach to characterize the viromes of 58 marine invertebrates species across three seas, demonstrated the hidden diversity of marine invertebrates RNA viruses.
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Attomolar sensing: Fabrication of surface-enhanced raman scattering substrate

Eurekalert - Jun 27 2021 - 00:06
Surface-enhanced Raman scattering (SERS) permits multidisciplinary trace analyses and the potential detection of single molecules. Shi Bai and Koji Sugioka from RIKEN report a comprehensive review of recent progress in strategies for the fabrication of highly sensitive SERS substrates. Femtosecond laser-based techniques are discussed as a versatile tool for the fabrication of SERS substrates. Several approaches are highlighted for enhancing the performance of SERS sensing devices, and real-time sensing and biological applications are reviewed.
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Has the stilling of the surface wind speed ended in China?

Eurekalert - Jun 27 2021 - 00:06
The continuous weakening of global land surface wind speed (stilling) has seriously affected the ecological environment and social economy, especially restricted the sustainable development of the wind energy industry. A recent study systematically answered the question of whether the surface wind speed in China is still weakening.
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Multi-material multi-photon 3D laser micro- and nanoprinting

Eurekalert - Jun 27 2021 - 00:06
Most realized 3D architectures are composed of only a single polymeric material. Here, we review 3D printing of multi-materials on the nano- and microscale. We start with material properties that have been realized, using multi-photon photoresists. Next, we review manual and automated processes achieving dissimilar material properties in a single 3D structure by sequentially photo-exposing multiple photoresists and by controlled stimuli of a single photoresist. Instructive examples from biology, optics, mechanics, and electronics are discussed.
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