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New super-resolution technique allows for more detailed brain imaging
A new imaging technique has the potential to detect neurological disorders--such as Alzheimer's disease--at their earliest stages, enabling physicians to diagnose and treat patients more quickly. Termed super-resolution, the imaging methodology combines position emission tomography (PET) with an external motion tracking device to create highly detailed images of the brain. This research was presented at the Society of Nuclear Medicine and Molecular Imaging's 2021 Virtual Annual Meeting.
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RUDN University scientists in pharmaceutical technology proved effectiveness of new dosage form
RUDN University scientists together with colleagues from Switzerland proved in a clinical trial the effectiveness of a new dosage form -- amorphous solid dispersion. This is the first such study in humans to show the mechanism of action of this form of drug release. In the future, it will help to increase the effectiveness of drugs and use new active substances for the treatment
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Boundary of heliosphere mapped for the first time
For the first time, the boundary of the heliosphere has been mapped, giving scientists a better understanding of how solar and interstellar winds interact.
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Radiotracer effective for detection and assessment of lung fibrosis
Positron emission tomography (PET) using a 68Ga-labeled fibroblast activation protein inhibitor (FAPI) can noninvasively identify and monitor pulmonary fibrosis, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting. By binding to activated fibroblasts present in affected lungs, FAPI-PET allows for direct imaging of the disease process.
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COVID-19 can cause severe inflammation in the brain
Various immune cells in the brainstem cause formation of inflammatory nodules
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Using machine learning and radar to better understand storm surge risk
The types of land around us play an important role in how major storms will unfold -- flood waters may travel differently over rural versus urban areas, for example. However, it's challenging to get an accurate picture of land types using only satellite image data because it is so difficult to interpret.Researchers at the Cockrell School of Engineering have, for the first time, applied a machine learning algorithm to measure the surface roughness of different types of land with a high level of detail.
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Rice lab peers inside 2D crystal synthesis
Rice University theorists simulate the molecular transitions that take place inside a furnace to create 2D molybdenum disulfide, a semiconductor that could find a home in next-generation electronics.
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Nanoparticle Therapy Shows Early Promise at Preventing a Rare, Fatal Newborn Lung Disease
Experts at Cincinnati Children's make early-stage progress at using nanoparticles to deliver treatment for rare lung disease. Details online today in Circulation.
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New gene therapy uses Tylenol to combat genetic diseases
Oregon Health & Science University researchers have developed a new approach to gene therapy that uses the common pain reliever acetaminophen to force a variety of genetic diseases into remission.
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Understanding what drives a liver cell to be a liver cell and not another cell type
Medical University of South Carolina researchers have discovered a gatekeeper protein that destines developing cells in an embryo to become liver cells. It exposes the genetic material of the cells and marks them as 'ready' for differentiation, i.e., transformation into liver cells, when developmental conditions are right. The findings, published in Cell Reports, could help scientists to better understand why liver cells do not develop correctly in children with inherited liver diseases.
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Improving dialysis through design
A multidisciplinary team from Washington University School of Medicine in St. Louis and the university's McKelvey School of Engineering have devised a new way to design grafts that decreases the risk of clotting, ultimately relieving people of the pain, inconvenience and disruption of this critical treatment.
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Study finds that inflammatory processes are altered in the brains of people with OUD
Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths--nearly 50,000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical models, an understanding of the biological alterations that occur in the brains of people who chronically use opioids and who are diagnosed with OUD remains limited.
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Physical activity may curb health care worker burnout
Investing in more physical activity programming could mitigate the effects of stress and improve worker mental and emotional health.
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Study finds links between Whites having Black neighbors and party affiliation
White men who had a Black neighbor when they were growing up are more likely to be Democrats and less likely to be Republican, an influence that can last several decades later.
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Trions exhibit novel characteristics in moiré superlattices
By shining laser light on semiconducting moiré superlattices formed by stacking two atomically thin materials -- monolayer tungsten diselenide (WSe2) and monolayer molybdenum diselenide (MoSe2) -- a team led by researchers at the University of California, Riverside, and Academia Sinica in Taiwan found a new class of electronic excited states called "moiré trions." The study opens up new opportunities to develop trion-based quantum optical emitters and offers new approaches to explore moiré physics.
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Financial toxicity impacts nearly 50% of women with gynecologic cancer
Researchers report on how a diverse cohort of gynecologic cancer patients are affected by financial distress, also called "financial toxicity" in acknowledgment of the health hazards it can pose, in the International Journal of Gynecological Cancer.
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New model identifies levers for stability for Fannie Mae and Freddie Mac credit
In a new article, an economist proposes a scenario in which large lenders temporarily boost high-risk activity at the end of a boom. According to her model, lenders with many outstanding mortgages have incentives to extend risky credit to prop up housing prices, which lessens the losses on their outstanding portfolio of mortgages.
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COVID-19 PCR tests can be freeze dried
In fighting COVID-19, it's not just the vaccines that require complicated cold supply chains and refrigerated storage. Polymerase chain reaction (PCR) tests also have enzymes and reagents that need to be frozen. Northwestern University researchers have discovered that commercially available PCR tests can withstand the freeze-drying process, making them shelf-stable for up to 30 days and 50 degrees Celsius (122 degrees Fahrenheit), without sacrificing sensitivity and accuracy. The new strategy could help ease logistical challenges, making tests more available.
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Designing public institutions that foster cooperation
People are more likely to cooperate with those they see as 'good.' Using a mathematical model, University of Pennsylvania researchers found it's possible to design systems that assess and broadcast participants' reputations, leading to high levels of cooperation and adherence.
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Researchers discover a key cause of energy loss in spintronic materials
A study led by University of Minnesota researchers uncovered a property of magnetic materials that will allow engineers to develop more efficient spintronic devices in the future, which could lead to faster and more efficient computing and data storage.
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