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The investigational therapeutic ficlatuzumab in combination with chemotherapy showed signs of clinical efficacy in patients with relapsed/refractory acute myeloid leukemia.

A team of researchers from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the University of Liège and the Helmholtz Institute Erlangen-Nürnberg for Renewable Energy have developed a microswimmer that appears to defy the laws of fluid dynamics: their model, consisting of two beads that are connected by a linear spring, is propelled by completely symmetrical oscillations. The findings have been published in the academic journal 'Physical Review Letters'.

Migration is a major phenomenon across developing economies. Marketers and policymakers should harness the power of migrants' remittances--both economic and social--to allocate marketing resources.

Satellite observations of XCO2 show greater biases apparently over oceans than over the land surface. However, no effective ways to evaluate space-time XCO2 variations over wide geographical areas exist. Observations on commercial ship tracks and aircraft routes, together with atmospehric model calculations, provide a new reference XCO2 dataset for the otherwise inaccesible areas of the world. High quality satellite observations are a requirement for better understanding of the carbon cycle in response to climate change.

This Oncotarget finding might have potential therapeutic implications, as anti-EGFR could be reconsidered in primarily RAS mutant patients reverted to a wild-type status after bevacizumab exposure.

A new study from WCS and WWF reveals that nearly 20 percent of tropical Intact Forest Landscapes (IFLs) overlap with concessions for extractive industries such as mining, oil and gas.

Short-term financial difficulties prevent poor people in Germany from voting and participating in politics. Such are the findings of a study by Max Schaub, a research fellow at the WZB Berlin Social Science Center (WZB), published in American Political Science Review. Among individuals at risk of poverty, both turnout intentions and actual turnout are reduced by 5 percentage points when election days coincide with phases of acute financial hardship.

Using a D-Wave quantum-annealing computer as a testbed, scientists at Los Alamos National Laboratory have shown that it is possible to isolate so-called emergent magnetic monopoles, a class of quasiparticles, creating a new approach to developing "materials by design."

Science snapshots from Berkeley Lab: Energy-saving windows, microbial fingerprints, lithium-ion batteries & fuel cells

A new study by Vanderbilt University Medical Center researchers of more the 400,000 Medicare patients taking medications for insomnia found that the risk of death is increased when either benzodiazepines or "z-drugs" are taken with opioids.

Wildfire smoke may greatly increase susceptibility to SARS-CoV-2, the virus that causes COVID-19, according to new research from the Center for Genomic Medicine at the Desert Research Institute (DRI), Washoe County Health District (WCHD), and Renown Health (Renown) in Reno, Nev.

MIT engineers have created a nanoparticle for cancer diagnosis that can reveal the presence of cancerous proteins through a urine test, and can also function as an imaging agent, pinpointing the tumor location.

Tsukuba University researchers develop a scheduling algorithm that helps automated biology labs optimize their samples throughout experiments while adhering to time constraints set by perishable materials. This work may help robots more effectively process cellular assays and clinical blood tests.

More than 75% of women with Opioid Use Disorder report having had an unintended pregnancy, but they are less likely to use effective contraception compared to women who do not use drugs. Results from a multi-year trial found that a two-part intervention featuring co-located contraceptive services in opioid treatment programs and financial incentives could offer an effective solution.

An international research group, led by Jamey Marth, Ph.D., a professor at Sanford Burnham Prebys, has shown that the Neuraminidase 3 (Neu3) enzyme is responsible for the onset and progression of colitis -- a chronic digestive disease caused by inflammation of the colon.

The UK government's latest pandemic plan involves recklessly exposing millions of people to the acute and long-term effects of mass infection, warn experts in The BMJ today.

The presence of more than five symptoms of COVID-19 in the first week of infection is significantly associated with the development of long COVID, irrespective of age or gender, according to a new review published by the Journal of the Royal Society of Medicine.

There are substantial differences among low- and middle-income countries in the association between BMI and diabetes risk. Individual countries can optimize diabetes screening by tailoring guidelines to their specific population's risk threshold for BMI, age and gender. In some parts of the world, diabetes risk is greater at lower BMI thresholds and in younger ages than reflected in currently used cutoffs.

An observational study of more than 70,000 people in 302 UK hospitals finds that one in two people hospitalized with COVID-19 developed at least one complication. The new study, published in The Lancet, is the first to systematically assess a range of in-hospital complications, and their associations with age, sex and ethnicity, and their outcomes for the patients.

Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection.