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Scientists uncover structure of light-driven enzyme with potential biofuel applications

Eurekalert - Apr 22 2021 - 00:04
Although many organisms capture and respond to sunlight, enzymes - proteins that catalyze biochemical reactions - are rarely driven by light. A new study captures the full cycle of complex structural changes in an enzyme called FAP as it transforms a fatty acid into alkanes or alkenes.
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MERS DNA vaccine induces immunity, protects from virus challenge in preclinical model

Eurekalert - Apr 22 2021 - 00:04
A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at Wistar induced potent immune responses and afforded protective efficacy in non-human primate models when given intradermally in abbreviated, low-dose immunization regimen.
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Researchers identify predictive factors of delirium in Sub-Saharan Africa

Eurekalert - Apr 22 2021 - 00:04
Severity of illness, history of stroke, and being divorced or widowed were independently predictive of delirium in hospitalized patients in Zambia, according to a study published in PLOS ONE.
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Researchers show how 'theory of mind' influences advertising skepticism

Eurekalert - Apr 22 2021 - 00:04
Product marketers should be clear in their messaging to avoid customer skepticism that makes them feel duped, according to University of Oregon research. At issue in a new study was a social-cognitive construct called theory of mind, which considers how well people assess the mental states and apparent goals of others. Turns out, it affects a person's evaluation and willingness to buy a product.
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Stress test finds cracks in the resistance of harmful hospital bugs

Eurekalert - Apr 22 2021 - 00:04
Research has identified critical factors that enable dangerous bacteria to spread disease by surviving on surfaces in hospitals and kitchens.
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Ground and satellite observations map building damage after Beirut explosion

Eurekalert - Apr 22 2021 - 00:04
Days after the 4 August 2020 massive explosion at the port of Beirut in Lebanon, researchers were on the ground mapping the impacts of the explosion in the port and surrounding city. The goal was to document and preserve data on structural and façade damage before rebuilding.
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3D printed models provide clearer understanding of ground motion

Eurekalert - Apr 22 2021 - 00:04
It seems like a smooth slab of stainless steel, but look a little closer, and you'll see a simplified cross-section of the Los Angeles sedimentary basin. Caltech researcher Sunyoung Park and her colleagues are printing 3D models like the metal Los Angeles proxy to provide a novel platform for seismic experiments.
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Can machine learning improve debris flow warning?

Eurekalert - Apr 22 2021 - 00:04
Machine learning could provide up an extra hour of warning time for debris flows along the Illgraben torrent in Switzerland, researchers report at the Seismological Society of America (SSA)'s 2021 Annual Meeting
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Blacks, hispanics, impoverished have worse survival rates among teens, adults under 40 with cancer

Eurekalert - Apr 22 2021 - 00:04
DALLAS - April 22, 2021 - Being Black or Hispanic, living in high-poverty neighborhoods, and having Medicaid or no insurance coverage are associated with higher mortality in men and women under 40 with cancer, a review by UT Southwestern Medical Center researchers found.
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COVID-19 vaccine development built on >$17 billion in NIH funding for vaccine technologies

Eurekalert - Apr 22 2021 - 00:04
The unprecedented development of COVID-19 vaccines less than a year after discovery of this virus was enabled by more than $17 billion of research on vaccine technologies funded by the NIH prior to the pandemic, according to new research from Bentley University's Center for Integration of Science and Industry. The article, "NIH funding for vaccine readiness before the COVID-19 pandemic," demonstrates the critical role this broad foundation of government-funded research plays in ensuring vaccine readiness.
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Among COVID-19 survivors, an increased risk of death, serious illness

Eurekalert - Apr 22 2021 - 00:04
Researchers at Washington University School of Medicine in St. Louis showed that COVID-19 survivors -- including those not sick enough to be hospitalized -- have an increased risk of death in the six months following diagnosis with the virus. They also have catalogued the numerous diseases associated with COVID-19, providing a big-picture overview of the long-term complications of COVID-19 and revealing the massive burden this disease is likely to place on the world's population in the coming years.
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During pandemic's first 9 months, depression and anxiety increased sharply among Americans

Eurekalert - Apr 22 2021 - 00:04
Boston College researchers found that 50 percent of adults reported anxiety and 44 percent reported depression between April and November 2020 - rates six times higher than 2019 - according to a new report in the journal Translational Behavioral Medicine. Rates of anxiety and depression were nearly twice as high for young adults than for older adults, and were also elevated among Blacks and Hispanics, less educated adults, women, and single parents, according to surveys of 1.5 million Americans.
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Minimally invasive retinal reattachment procedure leads to superior photoreceptor integrity

Eurekalert - Apr 22 2021 - 00:04
A new study reinforces pneumatic retinopexy (PnR) as the better first-line retinal reattachment technique to achieve the best visual outcomes.
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California's wildfire season has lengthened, and its peak is now earlier in the year

Eurekalert - Apr 22 2021 - 00:04
Researchers at the University of California, Irvine have analyzed CALFIRE wildfire statistics from 2000 to 2019, comparing them with data from 1920 to 1999, to learn that the annual burn season has lengthened in the past two decades and that the yearly peak has shifted from August to July. A new study on the subject was published today in Nature Scientific Reports.
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Firearms laws curb rates of gun violence across United States

Eurekalert - Apr 22 2021 - 00:04
States with stricter firearms laws reported lower suicide and homicide rates, according to a Rutgers study.
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Uniquely sharp X-ray view

Eurekalert - Apr 22 2021 - 00:04
Researchers at the Paul Scherrer Institute PSI have succeeded for the first time in looking inside materials using the method of transient grating spectroscopy with ultrafast X-rays at SwissFEL. The experiment at PSI is a milestone in observing processes in the world of atoms. The researchers are publishing their research results today in the journal Nature Photonics.
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Transport phenomena at the nanoscale

Eurekalert - Apr 22 2021 - 00:04
Excitation gratings created by interference of two light waves on a material allow investigating transport phenomena at a scale comparable to their wavelength. Going to the X-rays allows accessing these phenomena at the nanoscale.
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Miniaturized models of neuron-muscle interactions give insight in ALS

Eurekalert - Apr 22 2021 - 00:04
Researchers have developed a new miniaturized model of neuromuscular junction formation that will have broad applications in studying motor neuron pathology and the discovery of potential therapeutics in ALS.
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Urgent shortage of evidence for safe withdrawal from antidepressants

Eurekalert - Apr 22 2021 - 00:04
A new study has highlighted that while much is known about the ever increasing uptake of antidepressant medications around the world, there is very little evidence on safe and effective approaches to discontinuing treatment.
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'Stickiness' key to better diagnostics and pharmaceuticals

Eurekalert - Apr 22 2021 - 00:04
The 'stickiness', or viscosity, of microscopic liquids can now be measured thousands of times faster than ever before, potentially leading to better understanding of living cells, disease diagnostics and pharmaceutical testing.
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