Brain

Piglets in mazes provide insights into human cognitive development

URBANA -- Events that take place early in life almost certainly have consequences for later cognitive development. Establishing the connections is difficult, however, because human infants cannot be used as laboratory subjects.

Rodney Johnson and his collaborators have developed an alternative model for studying infant brain development. "Assistant professor Ryan Dilger and I became interested in establishing the neonatal piglet as a model of human brain and cognitive development 3 or 4 years ago," he said.

Texas A&M biologists prove ZOLOFT packs potential to fight fungal meningitis

New research conducted by biologists at Texas A&M University suggests that ZOLOFT®, one of the most widely prescribed antidepressants in the world, also packs a potential preventative bonus — potent mechanisms capable of inhibiting deadly fungal infections.

Spatial skills may be improved through training, new review finds

Spatial skills--those involved with reading maps and assembling furniture--can be improved if you work at it, that's according to a new look at the studies on this topic by researchers at Northwestern University and Temple.

The research published this month in Psychological Bulletin, the journal of the American Psychological Association, is the first comprehensive analysis of credible studies on such interventions.

Force of habit: Stress hormones switch off areas of the brain for goal-directed behaviour

Cognition psychologists at the Ruhr-Universität together with colleagues from the University Hospital Bergmannsheil (Prof. Dr. Martin Tegenthoff) have discovered why stressed persons are more likely to lapse back into habits than to behave goal-directed. The team of PD Dr. Lars Schwabe and Prof. Dr. Oliver Wolf from the Institute for Cognitive Neuroscience have mimicked a stress situation in the body using drugs. They then examined the brain activity using functional MRI scanning.

New drug could treat Alzheimer's, multiple sclerosis and brain injury

CHICAGO --- A new class of drug developed at Northwestern University Feinberg School of Medicine shows early promise of being a one-size-fits-all therapy for Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic brain injury by reducing inflammation in the brain.

Northwestern has recently been issued patents to cover this new drug class and has licensed the commercial development to a biotech company that has recently completed the first human Phase 1 clinical trial for the drug.

New research determines how a single brain trauma may lead to Alzheimer's disease

BOSTON (July 24, 2012, 5:00PM EST)—A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain.

New publication examines effect of early drug administration on Alzheimer's animal model

LEXINGTON, Ky. (July 25, 2012) — In a study published June 25 in the Journal of Neuroscience, a collaborative team of researchers led by Linda J. Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, and D. Martin Watterson of the Northwestern University Feinberg School of Medicine, present results showing that a new central nervous system drug compound can reduce Alzheimer's pathology in a mouse model of the disease. The drug, called MW-151, is a selective suppressor of brain inflammation and overproduction of proinflammatory molecules from glial cells.

Red potato chips: Segmentation cues can substantially decrease food intake

Once you pop the top of a tube of potato chips, it can be hard to stop munching its contents. But Cornell University researchers may have found a novel way to help: edible serving-size markers that act as subconscious stop signs.

Yoga reduces stress; now it's known why

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer's and dementia. Now they know why.

New probe provides vital assist in brain cancer surgery

A new probe developed collaboratively at Norris Cotton Cancer Center and Dartmouth College's Thayer School of Engineering uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.

'Weakest links' show greatest gains in relay races

EAST LANSING, Mich. — The inferior members of swimming or running relay teams – those athletes who fared poorest in individual races – showed the greatest gains when performing as part of a team, and those gains were even greater during final races as opposed to preliminary races.

The new research from Michigan State University's Deborah Feltz and Kaitlynn Osborn provides some of the first real-world support for the Köhler motivation effect, which describes how less capable individuals perform better when performing a task with others as opposed to individually.

Mindfulness meditation reduces loneliness in older adults, Carnegie Mellon study shows

PITTSBURGH—For older adults, loneliness is a major risk factor for health problems — such as cardiovascular disease and Alzheimer's — and death. Attempts to diminish loneliness with social networking programs like creating community centers to encourage new relationships have not been effective.

Wayne State develops better understanding of memory retrieval between children and adults

DETROIT — Neuroscientists from Wayne State University and the Massachusetts Institute of Technology (MIT) are taking a deeper look into how the brain mechanisms for memory retrieval differ between adults and children. While the memory systems are the same in many ways, the researchers have learned that crucial functions with relevance to learning and education differ. The team's findings were published on July 17, 2012, in the Journal of Neuroscience.

Ecopsychology -- a major new area of study

New Rochelle, NY, July 24, 2012—Hundreds of colleges and universities around the world are offering courses and even graduate degrees in ecopsychology and other forms of environmentally focused psychology. Ecopsychology examines the psychological, spiritual, and therapeutic aspects of human-nature relationships, concern about environmental issues, and responsibility for protecting natural places and other species.

Classifying neural circuit dysfunctions using neuroeconomics

Philadelphia, PA, July 24, 2012 – The traditional approach to psychiatric diagnosis is based on grouping patients on the basis of symptom clusters. This approach to diagnosis has a number of problems, as symptoms are not necessarily specific to a single diagnosis. Symptoms may vary among patients with a particular diagnosis, and there are no clear diagnostic biomarkers or tests for psychiatry as there are for other areas of medicine.