Brain

Neural precursor cells induce cell death in certain brain tumors

Neural precursor cells (NPC) in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma (GBM), which are among the most common and most aggressive tumors. Now researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité – Universitätsmedizin Berlin have deciphered the underlying mechanism of action with which neural precursor cells protect the young brain against these tumors.

Powerful class of antioxidants may be potent Parkinson's treatment

AUGUSTA, Ga. – A new and powerful class of antioxidants could one day be a potent treatment for Parkinson's disease, researchers report.

A class of antioxidants called synthetic triterpenoids blocked development of Parkinson's in an animal model that develops the disease in a handful of days, said Dr. Bobby Thomas, neuroscientist at the Medical College of Georgia at Georgia Health Sciences University and corresponding author of the study in the journal Antioxidants & Redox Signaling.

Neuroeconomics to study decision-making in anxious individuals

Philadelphia, PA, July 23, 2012 – Anxiety disorders affect approximately 40 million American adults each year, and although they are treatable, they often cause significant distress.

The excessive fear and dread that accompanies anxiety disorders clearly influences the everyday decision-making processes of anxious individuals. Despite its importance, "there is surprisingly little research on how anxiety disorders influence decisions," commented neuroscientist Dr. Elizabeth Phelps, who co-authored this new review with Dr. Catherine Hartley, both of New York University.

Snacking and BMI linked to double effect of brain activity and self-control

Snack consumption and BMI are linked to both brain activity and self-control, new research has found.

The research, carried out by academics from the Universities of Exeter, Cardiff, Bristol, and Bangor, discovered that an individual's brain 'reward centre' response to pictures of food predicted how much they subsequently ate. This had a greater effect on the amount they ate than their conscious feelings of hunger or how much they wanted the food,

Study offers new clue on how brain processes visual information

WINSTON-SALEM, N.C. – July 23, 2012 – Ever wonder how the human brain, which is constantly bombarded with millions of pieces of visual information, can filter out what's unimportant and focus on what's most useful?

Revealed: Brain functions during visual searches

You're headed out the door and you realize you don't have your car keys. After a few minutes of rifling through pockets, checking the seat cushions and scanning the coffee table, you find the familiar key ring and off you go. Easy enough, right? What you might not know is that the task that took you a couple seconds to complete is a task that computers –– despite decades of advancement and intricate calculations –– still can't perform as efficiently as humans: the visual search.

Stroke caregivers are at risk for depression

MAYWOOD, Ill. - Caregivers of stroke survivors are at risk for developing depression and complications from chronic stress, according to a study published by researchers at the Loyola University Chicago Marcella Niehoff School of Nursing (MNSON) in the latest issue of Biological Research for Nursing.

Cell research opens new avenues in combating neurodegenerative diseases

Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular processes underlying these conditions.

Triangles guide the way for live neural circuits in a dish

Korean scientists have used tiny stars, squares and triangles as a toolkit to create live neural circuits in a dish.

They hope the shapes can be used to create a reproducible neural circuit model that could be used for learning and memory studies as well as drug screening applications; the shapes could also be integrated into the latest neural tissue scaffolds to aid the regeneration of neurons at injured sites in the body, such as the spinal cord.

Better management of traumatic brain injury

New treatments to lessen the severity of the more than 21,000 Traumatic Brain Injury (TBI) cases that occur in Australia each year are on the horizon.

Published today in the leading neurology journal, Brain, a study led by researchers from Monash University's Australian Centre for Blood Diseases (ACBD) revealed how inhibiting certain enzymes decreased the severity of TBI, providing a target for future treatments.

Blood vessel forming potential of stem cells from human placenta and umbilical cord blood

Tampa, Fla. (July 19, 2012) – A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic.

Decoding brains: Scientists read monkeys' inner thoughts

Anyone who has looked at a recording of the electrical activity of a single neuron in the brain must have wondered how any useful information could be extracted from such a frazzled signal. Researchers have previously discovered that clear information can be obtained by decoding the activity of large populations of neurons but now scientists at Washington University in St. Louis, who were decoding brain activity while monkeys reached around an obstacle to touch a target, have come up with two remarkable results.

In utero exposure to diesel exhaust a possible risk factor for obesity

Bethesda, MD—Pregnant mice exposed to high levels of air pollution gave birth to offspring with a significantly higher rate of obesity and insulin resistance in adulthood than those that were not exposed to air pollution. This effect seemed especially prevalent in male mice, which were heavier regardless of diet. These findings, published online in the FASEB Journal, suggests a link between diesel exhaust exposure in utero and bulging waistlines in adulthood.

Understanding flirtation in negotiation, 'shooter bias,' love during marriage, and more

The benefits of flirtation in negotiation

Crossing the gap: Civil engineers develop improved method for detecting, measuring bridge damage

MANHATTAN, KAN. -- A ratings system developed by a group of Kansas State University researchers could keep bridges safer and help prevent catastrophic collapses.

Hayder Rasheed, associate professor of civil engineering, and Yacoub Najjar, professor of civil engineering, are collaborating to better detect and measure damage in concrete bridges. Ahmed Al-Rahmani, doctoral student in civil engineering, United Arab Emirates, has also been involved in the project.