Brain

CHAMPAIGN, Ill. — A new study finds that fruit flies exposed to methamphetamine drastically reduce their food intake and increase their physical activity, just as humans do. The study, which tracked metabolic and behavioral changes in fruit flies on meth, indicates that starvation is a primary driver of methamphetamine-related death in the insects.

The new findings are described in The Journal of Toxicological Sciences.

People with mental health problems have a lower life expectancy, according to a large-scale population based study published today in the British Medical Journal. The findings may prompt further research into the way doctors treat patients with even mild psychological problems.

A team of researchers from UCL (University College London) and the University of Edinburgh analysed data from over 68,000 adults aged 35 years and over who took part in the Health Survey for England from 1994 to 2004.

Cold Spring Harbor, NY – Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition.

DETROIT -- Wayne State University School of Medicine researchers, working with colleagues in Canada, have found that one or more substances produced by a type of immune cell in people with multiple sclerosis (MS) may play a role in the disease's progression. The finding could lead to new targeted therapies for MS treatment.

ANN ARBOR, Mich.—Concussions and even lesser head impacts may speed up the brain's natural aging process by causing signaling pathways in the brain to break down more quickly than they would in someone who has never suffered a brain injury or concussion.

In a new study published in the journal Vision Research, researchers at the University of Southern California show that the eyes and attention of men and women meander in distinctly different ways.

The article, authored by Dr. Laurent Itti and doctoral student John Shen, challenges the way scientists generally conceive of attention, or how sensory information is prioritized. While previous study of vision and attention had disregarded individual factors such as sex, race and age, Itti and Shen demonstrated that men and women pay visual attention in different ways.

CORVALLIS, Ore. – A dramatic increase in childhood obesity in recent decades may have impacts that go beyond the usual health concerns – it could be disrupting the timing of puberty and ultimately lead to a diminished ability to reproduce, especially in females.

A body of research suggests that obesity could be related to growing problems with infertility, scientists said in a recent review, in addition to a host of other physical and psycho-social concerns. The analysis was published in Frontiers in Endocrinology.

Brain-computer interfaces are at the cutting edge for treatment of neurological and psychological disorder, including Parkinson's, epilepsy, and depression. Among the most promising advance is deep brain stimulation (DBS) — a method in which a silicon chip implanted under the skin ejects high frequency currents that are transferred to the brain through implanted electrodes that transmit and receive the signals. These technologies require a seamless interaction between the brain and the hardware.

The presence of specific autoantibodies of the immune system is associated with blood vessel damage in the brain. These findings were made by Marion Bimmler, a graduate engineer of medical laboratory diagnostics at the Max Delbrück Center for Molecular Medicine Berlin-Buch and Dr. Peter Karczewski of the biotech company E.R.D.E.-AAK-Diagnostik GmbH in studies on a rat model. The researchers' results suggest that autoimmune mechanisms play a significant role in the pathogenesis and progression of Alzheimer's and vascular dementia (PloS ONE, doi:10.1371/journal.pone.0041602)*.

Washington D.C., July 31, 2012 – A study published in the July 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that diverted medical marijuana use among adolescents receiving treatment for substance abuse is very common.

Philadelphia, PA, July 31, 2012 – Mental disorders that emerge in childhood and adolescence, including attention-deficit disorder, depression, anxiety and substance abuse, constitute significant challenges to cognitive, emotional, and social development. As a result, it is perhaps not surprising that earnings and income are substantially reduced among people diagnosed with mental disorders.

An international team of scientists led by researchers at Mount Sinai School Medicine have discovered that a drug that had previously yielded conflicting results in clinical trials for Alzheimer's disease effectively stopped the progression of memory deterioration and brain pathology in mouse models of early stage Alzheimer's disease. The findings, published July 31, 2012 in Molecular Psychiatry, demonstrate renewed potential for this compound and could lead to clinical trials in patients with early stages of the disease.

A UH experiment takes an unconventional look at the treatment for domestic violence, otherwise known as intimate partner violence (IPV), by focusing on changing the perpetrators' psychological abuse during arguments rather than addressing his sexist beliefs.

During Alzheimer's disease, 'plaques' of amyloid beta (Ab) and tau protein 'tangles' develop in the brain, leading to the death of brain cells and disruption of chemical signaling between neurons. This leads to loss of memory, mood changes, and difficulties with reasoning. New research published in BioMed Central's open access journal Alzheimer's Research & Therapy, has found that up-regulating the gene Hes1 largely counteracted the effects of Ab on neurons, including preventing cell death, and on GABAergic signaling.

UC Irvine scientists have discovered intriguing differences in the brains and mental processes of an extraordinary group of people who can effortlessly recall every moment of their lives since about age 10.