Body

Prions can trigger 'stuck' wine fermentations, researchers find

A chronic problem in winemaking is "stuck fermentation," when yeast that should be busily converting grape sugar into alcohol and carbon dioxide prematurely shuts down, leaving the remaining sugar to instead be consumed by bacteria that can spoil the wine.

Are cigarette substitutes a safe alternative? It depends on user habits

CORAL GABLES, Fla (Aug. 26, 2014)-- Cigarette smoking kills approximately 440,000 Americans each year, according to the Centers for Disease Control and Protection. It's the leading cause of preventable death worldwide. In order to overcome this addiction, many people resort to nicotine replacement therapies.

Bradley Hospital collaborative study identifies genetic change in autism-related gene

PROVIDENCE, R.I. – A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities.

Yale study identifies possible bacterial drivers of IBD

Yale University researchers have identified a handful of bacterial culprits that may drive inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis, using patients' own intestinal immune responses as a guide.

The findings are published Aug. 28 in the journal Cell.

Trillions of bacteria exist within the human intestinal microbiota, which plays a critical role in the development and progression of IBD. Yet it's thought that only a small number of bacterial species affect a person's susceptibility to IBD and its potential severity.

Drug shows promise against Sudan strain of Ebola in mice

August 28, 2014 — (BRONX, NY) — Researchers from Albert Einstein College of Medicine of Yeshiva University and other institutions have developed a potential antibody therapy for Sudan ebolavirus (SUDV), one of the two most lethal strains of Ebola. A different strain, the Zaire ebolavirus (EBOV), is now devastating West Africa.

DeVincenzo study breakthrough in RSV research

MEMPHIS, Tenn. – The New England Journal of Medicine published research results on Aug. 21 from a clinical trial of a drug shown to safely reduce the viral load and clinical illness of healthy adult volunteers intranasally infected with respiratory syncytial virus (RSV).

Le Bonheur Children's Hospital and the University of Tennessee Health Science Center researcher Infectious Disease Specialist John DeVincenzo, MD, is lead author of this study.

Genomic sequencing reveals mutations, insights into 2014 Ebola outbreak

In response to an ongoing, unprecedented outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard University, in collaboration with the Sierra Leone Ministry of Health and Sanitation and researchers across institutions and continents, has rapidly sequenced and analyzed more than 99 Ebola virus genomes. Their findings could have important implications for rapid field diagnostic tests. The team reports its results online in the journal Science.

New research reveals how wild rabbits were genetically transformed into tame rabbits

The genetic changes that transformed wild animals into domesticated forms have long been a mystery. An international team of scientists has now made a breakthrough by showing that many genes controlling the development of the brain and the nervous system were particularly important for rabbit domestication. The study is published today in Science and gives answers to many genetic questions.

Less than $200 million would conserve precious Atlantic Forest in Brazil, say researchers

Brazil could conserve its valuable Atlantic Forest by investing just 0.01 per cent of its annual GDP, according to a new study.

The Atlantic Forest (Mata Atlântica) is one of the most important and threatened biodiversity hotspots in the world, containing the only living examples of nearly 10,000 species of plant and more bird species than all of Europe.

Penn-NIH team discover new type of cell movement

The discovery could have implications for understanding diseases such as cancer as well, because cancerous cells tend to move in distinct ways from normal cells.

"It might give us leverage to find out what is unique about cancer cells so we can target them therapeutically and not affect normal cells," Petrie said.

Importantly, these findings could have broader relevance to other biological systems where living cells are enmeshed within and surrounded by an extracellular matrix, such as in biofilms, which are associated with many human infectious diseases.

How the zebrafish gets its stripes

The zebrafish, a small fresh water fish, owes its name to a striking pattern of blue stripes alternating with golden stripes. Three major pigment cell types, black cells, reflective silvery cells, and yellow cells emerge during growth in the skin of the tiny juvenile fish and arrange as a multilayered mosaic to compose the characteristic colour pattern.

Second-hand e-cig smoke compared to regular cigarette smoke

E-cigarettes are healthier for your neighbors than traditional cigarettes, but still release toxins into the air, according to a new study from USC.

Scientists studying secondhand smoke from e-cigarettes discovered an overall 10-fold decrease in exposure to harmful particles, with close-to-zero exposure to organic carcinogens. However, levels of exposure to some harmful metals in second-hand e-cigarette smoke were found to be significantly higher.

Small molecule acts as on-off switch for nature's antibiotic factory

DURHAM, N.C. -- Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines.

Their hope now would be to see whether it is possible to manipulate this switch to make nature's antibiotic factory more efficient.

Healthy Moms program helps women who are obese limit weight gain during pregnancy

PORTLAND, Ore., August 28, 2014 — A new study finds that women who are obese can limit their weight gain during pregnancy using conventional weight loss techniques including attending weekly group support meetings, seeking advice about nutrition and diet, and keeping food and exercise journals.

Results of the Healthy Moms study, published in Obesity, also show that obese women who limit their weight gain during pregnancy are less likely to have large-for-gestational age babies which can complicate delivery and increase the baby's risk of becoming obese later in life.

University of Montana cicada study discovers 2 genomes that function as 1

MISSOULA, Mont. – Two is company, three is a crowd. But in the case of the cicada, that's a good thing.

Until a recent discovery by a University of Montana research lab, it was thought that cicadas had a symbiotic relationship with two important bacteria that live within the cells of its body. Since the insect eats a simple diet consisting solely of plant sap, it relies on these bacteria to produce the nutrients it needs for survival.