Body

February 4, 2013

In 2005, Susan Lolle and colleagues from Purdue University published a paper in Nature, concluding that Arabidopsis thaliana plants do not obey the laws of Mendelian inheritance (the idea that all genes are inherited from their parents). Instead, Lolle found that these plants were demonstrating genetic traits from older generations, which shouldn't be possible according to our current understanding of how genes are passed on.

Two wasp species, Calymmochilus dispar and Gelis apterus, have been recorded as parasitoids on ant-eating spiders in a study published in the open access journal ZooKeys. The host spider, Zodarion styliferum, belongs to the largest genus of predominantly ant-eating spiders.

Boston, MA, February 4, 2013 – A team of scientists just won a battle in the war against antibiotic-resistant "superbugs" -- and only time will tell if their feat is akin to the bacterial "Battle of Gettysburg" that turns the tide toward victory.

They won this particular battle, or at least gained some critical intelligence, not by designing a new antibiotic, but by interfering with the metabolism of the bacterial "bugs" – E. coli in this case – and rendering them weaker in the face of existing antibiotics, as reported today in Nature Biotechnology.

KNOXVILLE, TN – Since the mid-nineteenth century, maps have helped elucidate the deadly mysteries of diseases like cholera and yellow fever. Yet today's global mapping of infectious diseases is considerably unreliable and may do little to inform the control of potential outbreaks, according to a new systematic mapping review of all clinically important infectious diseases known to humans.

PITTSBURGH, Feb. 4, 2013 – University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

When deprived of a key protein, some cancer cells are unable to properly divide, a finding described in the cover story of the February issue of the Journal of Cell Science. This research is supported in part by a grant from the National Institutes of Health.

PHILADELPHIA (February 4, 2013) – Scientists at the Monell Center have identified the location and certain genetic characteristics of taste stem cells on the tongue. The findings will facilitate techniques to grow and manipulate new functional taste cells for both clinical and research purposes.

ARLINGTON HEIGHTS, Ill. (February 4, 2013) – Those living near the equator may find themselves sneezing and wheezing more than usual. And the reason may not be due to increasing pollen counts. According to a new study released today, in the February issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), living in locations closest to the equator can put you at increased risk of developing allergy and asthma.

New University of East Anglia research into the mating habits of a critically endangered sea turtle will help conservationists understand more about its mating patterns.

Research published today in Molecular Ecology shows that female hawksbill turtles mate at the beginning of the season and store sperm for up to 75 days to use when laying multiple nests on the beach.

It also reveals that these turtles are mainly monogamous and don't tend to re-mate during the season.

PHILADELPHIA - Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, the repair system breaks down and cancer can occur. Cells have two complicated ways to repair these breaks, which can affect the stability of the entire genome.

After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked the disease's reemergence to specific genetic anomalies.

The discovery, co-lead by William L. Carroll, MD, director of NYU Langone Medical Center's Cancer Institute, is reported in a study published online February 3, 2013, in Nature Genetics.

Scientists have identified the gene essential for survival of antibody-producing cells, a finding that could lead to better treatments for diseases where these cells are out of control, such as myeloma and chronic immune disorders.

DURHAM, N.C. – Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.

DURHAM, N.C. – By reproducing in the laboratory the complex interactions that cause human genes to turn on inside cells, Duke University bioengineers have created a system they believe can benefit gene therapy research and the burgeoning field of synthetic biology.

This new approach should help basic scientists as they tease out the effects of "turning on" or "turning off" many different genes, as well as clinicians seeking to develop new gene-based therapies for human disease.

Cold Spring Harbor, NY – A team of plant geneticists at Cold Spring Harbor Laboratory (CSHL) has successfully demonstrated what it describes as a "simple hypothesis" for making significant increases in yields for the maize plant.