Body

TSRI scientists create new tool for exploring cells in 3-D

LA JOLLA, CA - December 1, 2014 - Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research Institute (TSRI).

In a study published December 1 in the journal Nature Methods, the researchers demonstrated how the software, called cellPACK, can be used to model viruses such as HIV.

"We hope to ultimately increase scientists' ability to target any disease," said Art Olson, professor and Anderson Research Chair at TSRI who is senior author of the new study.

Lung cancer risk model refines decisions to screen

A new method for determining lung cancer risk could more efficiently identify individuals for annual screening and catch more cancers early, according to a study published in this week's PLOS Medicine. The study, conducted by Martin Tammemägi of Brock University, Canada, and colleagues, evaluates a lung cancer risk prediction model and identifies a risk threshold for selecting individuals for annual lung cancer screening.

People putting their lives at risk by dismissing cancer symptoms

People could be putting their lives at risk by dismissing potential warning signs of cancer as less serious symptoms, according to a Cancer Research UK-funded study* published in PLOS ONE today (Tuesday).

More than half (53 per cent) of 1,700** people who completed a health questionnaire said they had experienced at least one red-flag cancer 'alarm' symptom during the previous three months***. But only two per cent of them thought that cancer was a possible cause.

The ryanodine receptor: Calcium channel in muscle cells

Scientists decode the three-dimensional structure of the calcium channel with unprecedented accuracy.

(Photo Credit: MPI f. Molecular Physiology/ S. Raunser)

Source: Max-Planck-Gesellschaft

New study strengthens evidence of the connection between statin use and cataracts

Philadelphia, PA, December 2, 2014 - Few classes of drugs have had such a transformative effect on the prevention of cardiovascular disease (CVD) as have statins, prescribed to reduce total cholesterol and low-density lipoprotein cholesterol. However, some clinicians have ongoing concerns regarding the potential for lens opacities (cataracts) as a result of statin use. In an article in the Canadian Journal of Cardiology, researchers report increased risk for cataracts in patients treated with statins.

Want to get male millennials on board with your cause? Focus on feelings

This news release is available in French.

Montreal, December 2, 2014 -- "Selfish" may be the adjective most often attached to millennials. But new research from Concordia University shows that the young men and women who make up the millennial generation aren't so self-centred when it comes to supporting charities -- as long as marketers use the right tactics for each gender.

Intermittent fasting even with the occasional cheat day may help combat obesity

New research in mice suggests that restricting access to food to 8-12 hours rather than allowing constant access to food may help prevent and even reverse obesity and type 2 diabetes. The results of two studies publishing online December 2 in the Cell Press journal Cell Metabolism suggest that this time-restricted eating affects the balance of bacteria found in the gut. Researchers also found the occasional "cheat days" on weekends did not undo the benefits of time-restricted eating in mice.

Another case against the midnight snack

In the new study, Panda's group subjected nearly 400 mice, ranging from normal to obese, to various types of diets and lengths of time restrictions. They found that the benefits of time-restricted feeding showed up regardless of the weight of the mouse, type of diet and length of the time restriction (to some degree).

Vitamin supplement successfully prevents noise-induced hearing loss

Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3. This discovery has important implications not only for preventing hearing loss, but also potentially for treating some aging-related conditions that are linked to the same protein.

University of Illinois researchers develop inexpensive hydrolysable polymer

Researchers at the University of Illinois at Urbana-Champaign have figured out how to reverse the characteristics of a key bonding material--polyurea--providing an inexpensive alternative for a broad number of applications, such as drug delivery, tissue engineering, and packaging.

Fighting air pollution in China with social media

COLUMBUS, Ohio - The serious air pollution problem in China has attracted the attention of online activists who want the government to take action, but their advocacy has had only limited success, a new study has revealed.

Instead, much of the online conversation has been co-opted by corporations wanting to sell masks, filters and other products and by government officials advancing its own environmental narrative, the study finds.

New techniques for estimating Atlantic bluefin tuna reproduction

AMHERST, Mass. - Using a new approach for determining the age at sexual maturity for wild stocks of western Atlantic bluefin tuna, researchers led by Molly Lutcavage of the University of Massachusetts Amherst and Gilad Heinisch of Israel's Oceanographic and Limnological Research Center, suggest that these fish mature at a considerably younger age than cuurently assumed. These findings could lead to changes in how fisheries scientists estimate the population.

King Richard III -- case closed after 529 years

International research led by the University of Leicester published in Nature Communications reveals:

Health boost for fitness centers

Health is high on the agenda in many countries with efforts to get more people exercising in order to reduce the problems associated with obesity, such as diabetes, cardiovascular disease and cancer.

Unfortunately, risk assessment is inadequate in terms of sports facilities and many fitness programs rely on the participants taking out insurance and signing legal waivers rather than their being taught safe practices and given a safe environment in which to exercise.

Traces of Martian biological activity could be locked inside a meteorite

"So far, there is no other theory that we find more compelling," says Philippe Gillet, director of EPFL's Earth and Planetary Sciences Laboratory. He and his colleagues from China, Japan and Germany performed a detailed analysis of organic carbon traces from a Martian meteorite, and have concluded that they have a very probable biological origin. The scientists argue that carbon could have been deposited into the fissures of the rock when it was still on Mars by the infiltration of fluid that was rich in organic matter.