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Those wishing to prove themselves as "doers" must not only be hands-on and demonstrate proactive behavior but also have social acumen and a feel for favorable opportunities. Those who rely on personal initiative alone will quickly be standing there as an isolated troublemaker. This is what psychologists from the University of Bonn and their colleagues from Florida State University (USA) have discovered through surveying a variety of occupational categories. The results have been published online in the renowned "Journal of Management". The printed version will be published soon.

(Jena/Germany) Jena scientists have been successful in producing highly specific nanoparticles. Depending on the bound dye the particles are guided to the liver or to the kidney and deliver their payload of active ingredients directly to the targeted tissue. Moreover, the dyes enable the tracking of the transport processes by intravital microscopy or, in a non-invasive way, by multi spectral optoacoustic tomography. The reduction of cholesterol production induced by siRNA served as the proof-of-principle for the developed method.

The Ebola epidemic in West Africa has pushed the decades-long search for a treatment to a frenetic pace. Somewhere in the virus' deceptively simple structure is a key to taming it. To find that key, scientists are undertaking multiple strategies, some of which are being fast-tracked for human testing, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society.

Recent research from the Met Office and the University of East Anglia (UEA) suggests breaking the existing global and UK temperature records is much more likely due to human influence on the climate.

Early Figures Suggest Global Record Possible

The global mean temperature for January to October based on the HadCRUT4 dataset (compiled by the Met Office and UEA's Climatic Research Unit) is 0.57 °C (+/- 0.1) above the long-term (1961-1990) average. This is consistent with the statement from the World Meteorological Organization (WMO) today.

Researchers at the Mechanobiology Institute at the National University of Singapore have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome. This work was published in Science Signaling (Guo et al. E-cadherin interactome complexity and robustness resolved by quantitative proteomics, Science Signaling, 02 Dec 2014, Vol 7, Issue 354).

Unlocking the complexity of cell adhesion

Plastic is well-known for sticking around in the environment for years without breaking down, contributing significantly to litter and landfills. But scientists have now discovered that bacteria from the guts of a worm known to munch on food packaging can degrade polyethylene, the most common plastic. Reported in the ACS journal Environmental Science & Technology, the finding could lead to new ways to help get rid of the otherwise persistent waste, the scientists say.

Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over recent years. Globally, there are approximately 750,000 new cases of liver cancer reported each year. Importantly, population-based studies show that HCC ranks as the third leading cause of cancer-related deaths worldwide. Also, a large proportion of HCC patients display symptoms of intrahepatic metastases or postsurgical recurrence, with a five-year survival rate of around only 30-40%.

Current asthma treatments can alleviate wheezing, coughing and other symptoms felt by millions of Americans every year, but they don't get to the root cause of the condition. Now, for the first time, scientists are reporting a new approach to defeating asthma by targeting the trigger -- the allergen -- before it can spark an attack. They describe their new compound, which they tested on rats, in ACS' Journal of Medicinal Chemistry.

In order to observe the impact of climate change on soil microorganisms under as natural conditions as possible, the scientists transferred intact young beech seedlings from a cool, wet, northwest-exposed site of a slope approximately corresponding to present climatic conditions to a warmer site exposed to the southwest. This transfer simulated temperature and precipitation profiles as can be expected from climate change. "We tried to keep initial soil type and nutrient content sin soil as comparable as possible to avoid additional factors influencing our data"," said Prof. Dr.

Scientists have released details of a raft of new chemicals with potent anti-malarial properties which could open the way to new drugs to fight the disease.

A new paper in PNAS is the third published by the group at the Australian National University (ANU), which has collaborated with groups from around the globe to uncover potential ammunition in the fight against malaria.

Over 200 million people contract malaria each year, and the parasite that causes the disease has become resistant to most of the drugs currently available.

December 3, 2014 -- Individuals conceived in the severe Dutch Famine, also called the Hunger Winter, may have adjusted to this horrendous period of World War II by making adaptations to how active their DNA is. Genes involved in growth and development were differentially regulated, according to researchers at the Leiden University Medical Center, Harvard University, and Columbia University's Mailman School of Public Health.

TALLAHASSEE, Fla. -- A team led by Florida State University researchers has identified DNA elements in maize that could affect the expression of hundreds or thousands of genes.

"Maybe they are part of the machinery that allows an organism to turn hundreds of genes off or on," said Associate Professor of Biological Science Hank Bass.

New York, NY, December 2, 2014 - Immediate breast reconstruction following mastectomy is becoming more prevalent. However, in breast cancer patients undergoing simultaneous chemotherapy, thrombotic complications can arise that can delay or significantly modify reconstructive plans. Outcomes of cases illustrating potential complications are published in the current issue of Annals of Medicine and Surgery.

Hamilton, ON (Dec. 3, 2014) - Scientists at McMaster University have discovered that human stem cells made from adult donor cells "remember" where they came from and that's what they prefer to become again.

This means the type of cell obtained from an individual patient to make pluripotent stem cells, determines what can be best done with them. For example, to repair the lung of a patient with lung disease, it is best to start off with a lung cell to make the therapeutic stem cells to treat the disease, or a breast cell for the regeneration of tissue for breast cancer patients.

CAMBRIDGE, MA -- MIT biological engineers have created a new computer model that allows them to design the most complex three-dimensional DNA shapes ever produced, including rings, bowls, and geometric structures such as icosahedrons that resemble viral particles.