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Some RNA molecules have unexpected sugar coating

Eurekalert - May 17 2021 - 00:05
Sugars attach to certain RNA molecules on the outside membrane of the cell. The newly discovered "glycoRNAs" may be involved in immune signaling.
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Errors in large-scale and convective tropical precipitation simulations using current global models may impact climate feedback

Eurekalert - May 17 2021 - 00:05
A new study finds errors in convective/large-scale rainfall partitions can potentially cause different climate responses and considerable uncertainties in climate projections.
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"Heat not burn" product compared with cigarettes and e-cigarettes

Eurekalert - May 17 2021 - 00:05
"Heat not burn" product found to deliver less nicotine than cigarettes, has lower nicotine delivery than Juul, and was less effective in reducing urges to smoke, finds study by Queen Mary University of London.
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Skoltech researchers developed an enriched method for increasing the capacity of next-generation metal-ion battery cathode materials

Eurekalert - May 17 2021 - 00:05
Scientists at Skoltech Center for Energy Science and Technology have developed an enriched and scalable approach for increasing the capacity of a broad range of metal-ion battery cathode materials. An important advantage of the approach is its scalability. The process requires no sophisticated conditions and is relatively safe. Additionally, the reducing agents can be recycled after they react with the cathodes because their redox chemistry is reversible. These features make the method promising for large-scale applications.
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Climate policies, transition risk, and financial stability

Eurekalert - May 17 2021 - 00:05
The way in which banks react to climate risks and uncertainty could impact financial stability as well as the world's transition to a low-carbon economy. A new study by researchers from IIASA and the Vienna University of Economics and Business explored the role that banks' expectations about climate-related risks will play in fostering or hindering an orderly low-carbon transition.
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New combination immunotherapy plus ART expand innate cells critical to controlling HIV

Eurekalert - May 17 2021 - 00:05
Yerkes NPRC/Emory University and Institut Pasteur researchers have determined adding a combination immunotherapy to antiviral therapy (ART) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models. This finding is key for reducing reliance on ART and developing additional treatment options to control HIV/AIDS.
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Cypriot grapes perform well in heat and on taste

Eurekalert - May 17 2021 - 00:05
Researchers at the University of Adelaide have found several grape varieties native to Cyprus, which tolerate drought conditions better than some international varieties popular in Australia, contain chemical compounds responsible for flavours preferred by Australian consumers.
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High-intensity intermittent training improves spatial memory in rats

Eurekalert - May 17 2021 - 00:05
Despite lower exercise volume, HIIT was as effective as endurance running for improving exercise capacity and spatial memory. Researchers at the University of Tsukuba found that activity-specific physiological adaptations in the muscles and increased signaling and neurogenesis in the hippocampus underlie these improvements. Findings also suggested that benefits can potentially be optimized by tailoring exercise time and intensity.
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Cysteinylated albumin: A new early diagnostic marker for diabetic kidney disease

Eurekalert - May 17 2021 - 00:05
Japanese researchers have discovered that cysteinylated albumin (oxidized albumin) in serum can be used as an early diagnostic marker for diabetic kidney disease. Compared with urinary albumin, serum oxidized albumin not only reflects renal pathology at an earlier stage, but can also predict the progression of renal pathology by its degree of elevation. The researchers believe that it can be used as a new diagnostic marker for early diagnosis of diabetic kidney disease.
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Two biodiversity refugia identified in the Eastern Bering Sea

Eurekalert - May 17 2021 - 00:05
Scientists from Hokkaido University have used species survey and climate data to identify two marine biodiversity refugia in the Eastern Bering Sea - regions where species richness, community stability and climate stability are high.
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Gut hormone triggers craving for more proteins

Eurekalert - May 17 2021 - 00:05
A new study led by KAIST researchers using fruit flies reveals how protein deficiency in the diet triggers cross talk between the gut and brain to induce a desire to eat foods rich in proteins or essential amino acids. This finding reported in the May 5 issue of Nature can lead to a better understanding of malnutrition in humans.
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New epigenetic regulatory mechanisms involved in multiple myeloma growth

Eurekalert - May 17 2021 - 00:05
An international team of researchers has analyzed the function of the histone demethylase KDM5A in multiple myeloma, one of the three major hematological cancers, and clarified the mechanism by which it promotes myeloma cell proliferation. They also developed a novel KDM5 inhibitor and showed that it inhibits cancer cell growth in a myeloma mouse model. The researchers expect that new therapies targeting KDM5A will be developed in the future.
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COVID-19 vaccination: Thrombosis can be prevented by prompt treatment

Eurekalert - May 17 2021 - 00:05
A rare syndrome has been observed in people following vaccination against Covid-19. This involves thrombosis at unusual sites in the body, associated with a low thrombocyte count and a clotting disorder. In medical jargon, this syndrome is referred to as VITT (vaccine-induced thrombotic thrombocytopenia). Doctors at MedUni Vienna and Vienna General Hospital have now successfully treated an acute instance of this syndrome.
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Oncotarget: Phase 1 study of Z-Endoxifen in patients with solid tumors

Eurekalert - May 17 2021 - 00:05
The Oncotarget article provides evidence that antitumor activity and prolonged stable disease are achieved with Z-endoxifen despite prior tamoxifen therapy.
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Oncotarget: CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

Eurekalert - May 17 2021 - 00:05
CABYR expression in tumors was further confirmed by immunohistochemistry
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Stair climbing offers significant cardiovascular and muscular benefits for heart patients

Eurekalert - May 17 2021 - 00:05
A team of McMaster University researchers who studied heart patients found that stair-climbing routines, whether vigorous or moderate, provide significant cardiovascular and muscular benefits.
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Oncotarget: Caloric restriction creates a metabolic pattern of chronological aging delay

Eurekalert - May 17 2021 - 00:05
The Oncotarget authors propose a model of how the specific remodeling of cellular metabolism by caloric restriction contributes to yeast chronological aging delay.
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US nurses working in critical care have been severely impacted by the COVID-19 pandemic

Eurekalert - May 17 2021 - 00:05
The COVID-19 pandemic has, and will continue to have, a tremendous impact on ICU nurses' mental health and willingness to continue in the critical care work force, according to research presented at the ATS 2021 International Conference.
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New numerical method makes simulating landslide tsunamis possible

Eurekalert - May 17 2021 - 00:05
Researchers from Tohoku University have developed a new numerical method that paves the way for simulating landslide tsunamis.
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Global land use more extensive than estimated

Eurekalert - May 17 2021 - 00:05
Humans leave their "footprints" on the land area all around the globe. These land-use changes play an important role for nutrition, climate, and biodiversity. Scientists at the Karlsruhe Institute of Technology (KIT) combined satellite data with statistics from the past 60 years and found that global land-use changes affect about 32 percent of the land area. This means that they are about four times as extensive as previously estimated. The researchers publish their findings in the scientific journal Nature Communications.
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