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Weighted "lottery" provides greater access to scarce COVID-19 medications
A weighted "lottery" designed to increase access to the antiviral drug remdesivir during the May-July 2020 COVID-19 surge for those most affected by the coronavirus, including members of the Black, Latinx and indigenous communities, led to more equitable distribution of the badly needed medication, according to research presented at the ATS 2021 International Conference.
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Baby and regular-strength aspirin work equally well to protect heart health
Researchers found no significant differences in cardiovascular events or major bleeding in patients with pre-existing cardiovascular disease who were taking 81 milligrams (mg), also called baby aspirin, versus 325 mg of daily aspirin, according to new data presented at the American College of Cardiology's 70th Annual Scientific Session
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Sacubitril/valsartan does not outperform ACE inhibitor after heart attack
The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks. Findings from the PARADISE-MI trial were presented at the American College of Cardiology's 70th Annual Scientific Session.
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Left atrial appendage occlusion reduces stroke after heart surgery
Patients with an elevated risk of stroke due to heart rhythm problems, or atrial fibrillation (AFib), were much less likely to suffer a stroke after undergoing heart surgery if doctors concurrently performed an additional procedure, called left atrial appendage occlusion (LAAO), according to the results of a trial presented at the American College of Cardiology's 70th Annual Scientific Session.
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Left atrial appendage occlusion associated with low rate of stroke
Transcatheter left atrial appendage occlusion (LAAO) with a WATCHMAN device was associated with a low rate of stroke at one year even among older patients with atrial fibrillation (AFib) who faced a high risk for stroke or bleeding based on their previous health history, according to new data presented at the American College of Cardiology's 70th Annual Scientific Session.
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Apixaban not superior to standard care after TAVR
The blood thinner apixaban was not superior to standard of care following transcatheter aortic valve replacement (TAVR), according to findings from a new trial called ATLANTIS presented at the American College of Cardiology's 70th Annual Scientific Session.
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Shrinking planets could explain mystery of universe's missing worlds
Flatiron Institute researchers have made a breakthrough in accounting for the mysterious lack of exoplanets roughly double Earth's radius -- an enigma called the radius gap. Using data from the Kepler spacecraft, the researchers found that the sizes of the 'missing planets' depends on the ages of the planetary systems. Specifically, the researchers propose that gas-shrouded exoplanets shrink drastically over billions of years, leaping over the radius gap to become relatively smaller rocky super-Earths.
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Early biomarker warning of heart disease for diabetic patients
New research has shown that people with type 1 diabetes may have features of premature heart disease induced by the condition often before they even get their diagnosis.
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Low- and high-dose aspirin achieve similar protection, safety for those with heart disease
As presented at ACC.21 and published in NEJM, the findings from ADAPTABLE are from the largest aspirin dosing trial conducted in routine care and clinical settings using PCORnet, a national resource advancing more efficient clinical research. The study and trial were funded by the Patient-Centered Outcomes Research Institute and conducted by a research team led by the Duke Clinical Research Institute.
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Simple surgery prevents strokes in heart patients
The study tracked 4,811 people in 27 countries who are living with atrial fibrillation and taking blood thinners. Consenting patients undertaking cardiopulmonary bypass surgery were randomly selected for the additional left atrial appendage occlusion surgery; their outcomes compared with those who only took medicine. They were all followed for a median of four years.
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Rutgers reports first instance of COVID-19 triggering recurrent blood clots in arms
Researchers at Rutgers Robert Wood Johnson Medical School are reporting the first instance of COVID-19 triggering a rare recurrence of potentially serious blood clots in people's arms.
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Pandemic boosts demand for postal delivery of abortion pill
A new study has found that even with clinics nearby, many women choose telehealth visits and the US Postal Service for prescriptions.
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Terpen-tales: The mystery behind the unique fragrance of the lovely lavender
Scientists from China have sequenced and analyzed the genome of lavender to provide insights into what causes its distinct aroma. Their findings shed light into the evolution of this uniquely fragrant plant, which could pave the way for creating improved lavender varieties besides adding to existing knowledge on the evolution, phytochemistry, and ecology of Lamiaceae, the plant family to which lavender belongs.
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Etching process enhances the extraction of hydrogen during water electrolysis
Etching the oxide overlayers of metal phosphide electrocatalysts can accelerate the process of surface reconstruction and facilitate the formation of key intermediate phases for catalyzing water electrolysis.
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Compound may prevent risk of a form of arrhythmia from common medications
The team discovered a compound that prevents and even reverses the underlying physiological change that can lead some drugs to cause heart problems.
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People at high genetic risk for colorectal cancer benefit more from lifestyle changes
People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.
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New technology enables rapid sequencing of entire genomes of plant pathogens
Next-generation sequencing technology has made it easier than ever for quick diagnosis of plant diseases. "It's really exciting to see how sequencing technologies have evolved and how this new technology facilitates sequencing of entire genomes in such a short amount of time," said Yazmín Rivera, a plant pathologist with the United States Department of Agriculture's Plant Protection and Quarantine program, who recently published a research paper on the efficacy of Oxford Nanopore Technologies protocols.
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Harvesting light like nature does
A new class of bio-inspired two-dimensional (2D) hybrid nanomaterials mimic the ability of photosynthetic plants and bacteria.
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Heart attack recovery aided by injecting heart muscle cells that overexpress cyclin D2
In a large-animal study, researchers have shown that heart attack recovery is aided by injection of heart muscle cells derived from human induced pluripotent stem cell line, or hiPSCs, that overexpress cyclin D2. This research, published in the journal Circulation, used a pig model of heart attacks, which more closely resembles the human heart in size and physiology, and thus has higher clinical relevance to human disease, compared to studies in mice.
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Cataloging breast cells to find cancer origins
CSHL scientists genetically profiled thousands of cells in normal breast tissue to establish what types of cells tend to become cancerous. This catalog can help researchers develop preventive therapies.
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