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The article represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles. The Pr3+:LaF3 nanoparticles are promising platforms for cell nano-sensors.

Researchers led by Pere Roca-Cusachs at the Institute for Bioengineering of Catalonia (IBEC) and Isaac Almendros at IDIBAPS discover how force dynamics affect cells, and living tissues. The results give an insight into the critical mechanical processes that occur in different diseases such as cancer.

An international research team led by YAO Zhonghua from the Institute of Geology and Geophysics of the Chinese Academy of Sciences (IGGCAS) has explained the cause of Jupiter's X-ray aurorae, a mystery that has puzzled scientists for 40 years.

Using time- and spin-resolved methods at BESSY II, the physicists explored how, after optical excitation, the complex interplay in the behavior of excited electrons in the bulk and on the surface results in unusual spin dynamics. The work is an important step on the way to spintronic devices based on topological materials for ultrafast information processing.

Researchers from the University of Tsukuba find that the combined effects of ocean warming and acidification in temperate marine ecosystems are resulting in a loss of kelp habitat and a shift to a simple turf-dominated ecosystem. Such changes will lead to a loss of the ecosystem services provided by productive macroalgal forests or tropicalized coral-dominated reefs. These results highlight the need for reductions in greenhouse gas emissions.

An international team of scientists from Australia, USA, and France have analysed how the deep Pacific exchanges water with the surface ocean.

What The Study Did: National health care systems have different capacities to correctly identify people who died of COVID-19. Researchers in this study analyzed the gap between excess mortality and  COVID-19 confirmed mortality in 67 countries to determine the extent to which official data on COVID-19 deaths might be considered reliable.

What The Study Did: Researchers investigated whether death, other hospital outcomes and processes of care differed between patients cared for by female and male physicians at hospitals in Canada.

What The Study Did: The association between primary care payment models and the use of telemedicine for Medicare Advantage enrollees during the COVID-19 pandemic was examined in this study.

Using long wavelength near-infrared light, scientists at UC Davis developed a label-free microscopy approach that achieves a unique combination of deep, high resolution, and minimally invasive brain imaging. The technique images neurons and axonal myelination across the mouse neocortex and some sub-cortical regions, through the thinned skull. Now studies of brain disease can be conducted deep in the mouse brain through a minimally invasive and simple surgical preparation.

In the largest systematic review and meta-analysis to date on COVID-19 outcomes in individuals with psychiatric disorders, the odds of dying or being hospitalized following COVID-19 infection were determined to be twice as high in comparison to persons without mental disorders.*

Washington, DC / New Delhi, India - Researchers at CDDEP recently published 'Improving vaccination coverage and timeliness through periodic intensification of routine immunization: evidence from Mission Indradhanush' where they evaluated the performance of India's Mission Indradhanush (MI) child vaccination campaign -- a periodic intensification of the routine immunization program.

A Ludwig Cancer Research study has found that inducing random chromosome instability (CIN) events in mice for as little as one week is enough to trigger harmful chromosomal patterns in cells that spur the formation of tumors.

Neuromodulation at high spatial resolution is crucial for advancing understanding of brain circuits and treatment of neurological diseases. Here, a tapered fiber optoacoustic emitter (TFOE) is developed for stimulation of single neurons and subcellular structures. The TFOE enabled integration with patch clamp recording and unveiled cell-type-specific response of excitatory and inhibitory neurons to photoacoustic stimulation. TFOE provides a non-genetic single-cell and sub-cellular modulation platform, which could shed new insights into the mechanism of ultrasound neurostimulation.

When a liquid is cooled rapidly, it gains viscosity and eventually becomes a rigid solid glass. The point at which it does so is known as the glass transition. A collaborative research group has furthered our understanding of this phenomenon through the use of high entropy metallic glasses.

RUDN University biologists discovered the way how macrophages (the cells of the "first line" immune response) respond to inflammation and identified how the immune response depends on their origin. It turned out that when exposed to an inflammatory stimulus, two opposing mechanisms are activated in macrophages simultaneously -- inducing and inhibiting inflammation. These data can potentially be useful in the treatment of cancer, as targeted activation of macrophages will strengthen the immune response of the organism in the fight against a tumor.

Publication in Nature Communication: Neuro-evolutionary robotics is an approach to realize collective behaviors for swarms of robots. A comparative study of the most popular neuro-evolutionary methods shows that the control software produced by most of the analyzed methods gives good results in simulation.

Developed by two researchers at the University of Malaga, This methodology enables the reduction of costs and time in engineering design optimisation thanks to artificial intelligence

A new way of producing coherent light in the ultra-violet spectral region, which points the way to developing brilliant table-top x-ray sources, has been produced in research led at the University of Strathclyde.

The brain mechanisms underlying the suppression of fear responses have attracted a lot of attention as they are relevant for therapy of human anxiety disorders. Despite our broad understanding of the different brain regions activated during the experience of fear, how fear responses can be suppressed remains largely elusive. Researchers at the University of Bern and the Friedrich Miescher Institute in Basel have now discovered that the activation of identified central amygdala neurons can suppress fear responses.