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New approach eradicates breast cancer in mice
A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.
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Oral and general health associations using machine learning prediction algorithms
Alexandria, Va., USA - Muthuthanthrige Cooray, Tohoku University, Sendai, Japan, presented the oral session "Oral and General Health Associations Using Machine Learning Prediction Algorithms" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
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Enamel defects as biomarkers for exposure to environmental stressors
Alexandria, Va., USA - IADR President Pamela Den Besten presented and chaired the IADR President's Symposium "Enamel Defects as Biomarkers for Exposure to Environmental Stressors" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
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Policy changes to kidney allocation may unintentionally reduce access to transplant for South Carolina
Changes to the US kidney allocation system could result in reduced access to kidney transplants and longer times spent in line for rural patients according to new research. The OPTN addressed allocation inequalities by ensuring that all patients wait at least the same amount of time for a kidney rather than the previous geography-based model. These policy changes are also predicted to result in a 40% decline in kidney transplant volumes for South Carolina.
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Study links vaccine immune response to age
Older people appear to have fewer antibodies against the novel coronavirus, a new laboratory study from Oregon Health & Science University suggests. With vaccine uptake slowing in Oregon and across United States, researchers say their findings underscore the importance of promoting vaccinations in local communities.
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Existing drug is shown to inhibit SARS-CoV-2 virus
A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19.
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Why weren't New World rabbits domesticated?
Rabbits were raised for over a thousand years in Mexico without becoming domesticated. A new study finds that their solitary lifestyle and greater species diversity made domestication unlikely.
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Study: Ibrutinib effective treatment for difficult to treat forms of hairy cell leukemia
The oral targeted therapy drug ibrutinib is an effective treatment option for high-risk hairy cell leukemia, according to a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).
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Kids eat more fruit and vegetables with longer seated lunch time
When kids sit down to eat lunch at school, fruits and vegetables may not be their first choice. But with more time at the lunch table, they are more likely to pick up those healthy foods. If we want to improve children's nutrition and health, ensuring longer school lunch breaks can help achieve those goals, according to research from the University of Illinois.
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The challenge of capturing carbon
In the race to combat climate change, capturing carbon dioxide emissions has been touted as a simple road to reach net-zero emissions by 2050. While the science behind carbon capture is sound, current technologies are expensive and not optimized for all settings. A cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, highlights the current state of carbon capture and work being done to improve the process.
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Nanostructures enable record high-harmonic generation
Researchers at Cornell University have developed nanostructures that enable record-breaking conversion of laser pulses into high-harmonic generation, paving the way for new scientific tools for high-resolution imaging.
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Rounding errors could make certain stopwatches pick wrong race winners
Obtaining split-second measurements relies on faultlessly rounding a raw time recorded by a stopwatch or electronic timing system to a submitted time. Researchers at the University of Surrey found certain stopwatches commit rounding errors when converting raw times to final submitted times. In American Journal of Physics, they outline a series of computer simulations based on procedures for converting raw race times for display.
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Toward one drug to treat all coronaviruses
Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever. Now, researchers reporting in ACS' Journal of Proteome Research have analyzed viral proteins across 27 coronavirus species and thousands of samples from COVID-19 patients, identifying highly conserved sequences that could make the best drug targets.
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Thumb-sized device quickly 'sniffs out' bad breath
No one wants bad breath -- not when visiting friends and family, at a job interview, and especially not on a first date. Smelly breath can make things awkward, but it also is a natural warning sign, indicating that serious dental issues are occurring. Now, researchers reporting in ACS Nano have constructed a portable, thumb-sized device that diagnoses bad breath by quickly "sniffing" exhalations for the gas that makes it stinky -- hydrogen sulfide.
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Study innovates in gluten-free formulations, creating more palatable and nutritious bread
Study at the Federal University of São Paulo developed a recipe combining chickpea flour and psyllium, a plant-derived soluble fiber. The product is nourishing and rated highly by consumers in qualitative surveys.
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New scoring system for assessing wound healing
Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time. Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing
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Toxicity testing on the placenta and embryo
Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.
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A new model of coral reef health
Scientists have developed a new way to model and map the health of coral reef ecosystems using data collected on the Global Reef Expedition. This innovative method, presented today at the International Coral Reef Symposium (ICRS), can determine which natural and anthropogenic factors are most likely to lead to persistently vibrant coral and fish communities. Their findings can help scientists identify the reefs most likely to survive in a changing world.
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Sandia designs better batteries for grid-scale energy storage
Researchers at Sandia National Laboratories have designed a new class of molten sodium batteries for grid-scale energy storage. The new battery design was shared in a paper published today in the scientific journal Cell Reports Physical Science.
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New in the Hastings Center Report, July-August 2021
New in the Hastings Center Report: Should ethicists be activists? Four calls to action, and more in the July-August 2021 issue.
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