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Mount Sinai researchers develop novel therapy that could be effective in many cancers
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.
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Bacteria navigate on surfaces using a 'sense of touch'
EPFL researchers have characterized a mechanism that allows bacteria to direct their movement in response to the mechanical properties of the surfaces the microbes move on -- a finding that could help fight certain pathogens.
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Blushing plants reveal when fungi are growing in their roots
Scientists have created plants whose cells and tissues 'blush' with beetroot pigments when they are colonised by fungi that help them take up nutrients from the soil. This is the first time this vital, 400 million year old process has been visualised in real time in full root systems of living plants. Understanding the dynamics of plant colonisation by fungi could help to make food production more sustainable in the future.
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Research identifies potential role of 'junk DNA' sequence in aging, cancer
Researchers at Washington State University have recently identified a DNA region known as VNTR2-1 that appears to drive the activity of the telomerase gene, which has been shown to prevent aging in certain types of cells. Knowing how the telomerase gene is regulated and activated and why it is only active in certain cell types could someday be the key to understanding how humans age and how to stop the spread of cancer.
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Device cracks milk protein
After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.In the latest application, published in Molecules, College of Science and Engineering experts have combined the capabilities of the VFD with a new form of biosensor called TPE-MI, which is an aggregation-induced emission luminogen (AIEgen).
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Child mental health services lacking in high-income countries: SFU study finds
Most children with a mental health disorder are not receiving services to address their needs--according to a new study from researchers at Simon Fraser University's Children's Health Policy Centre. Their research was published this week in the journal Evidence-Based Mental Health.
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Scientists identify five new plant species in Bolivia
Scientists have identified five new plant species in the Bolivian Andes. The species are all part of the genus Jacquemontia, which are twining or trailing plants with pretty blue flowers.
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Water resources: Defusing conflict, promoting cooperation
The EU funded project DAFNE has developed a methodology for avoiding conflicts of use in transboundary rivers. The model-?based procedure allows for participatory planning and cooperative management of water resources. The aim is now for the DAFNE methodology to be implemented in other regions of the world.
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Chemotherapy can induce mutations that lead to pediatric leukemia relapse
A collaboration led by St. Jude Children's Research Hospital, Shanghai Children's Medical Center and others revealed how thiopurines produce mutations that lead to multi-drug resistant leukemia and relapse.
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Topology in biology
A phenomenon known from quantum systems could now make its way into biology:In a new study published in Physical Review X, researchers from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) in Goettingen show that the notion of topological protection can also apply to biochemical networks. The model which the scientists developed makes the topological toolbox, typically used only to describe quantum systems, now also available to biology.
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A new mathematical model assesses ICU patients' mortality risk
Researchers from the Universitat Autònoma de Barcelona (UAB) Department of Mathematics worked in collaboration with the Hospital de Mataró in developing an artificial intelligence-based model for predicting the risk of death of intensive care unit patients according to their characteristics. The model will improve the quality of care in these types of units.
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Study shows environmental link to herbicide-resistant horseweed
Horseweed is a serious threat to both agricultural crops and natural landscapes around the globe. In the U.S., the weed is prolific and able to emerge at any time of the year.
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Brain-repair discovery could lead to new epilepsy treatments
Researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.
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Southeastern US herbaria digitize three million specimens, now freely available online
The National Science Foundation recently provided funding to over 100 herbaria across the Southeast U.S. to digitize more than three million plant specimens collected by botanists and naturalists across the country. Researchers tracked the speed and productivity of staff and students who handled the specimens, from the collection drawers to online repositories, to provide institutions with a framework to better determine the time and money needed to digitize remaining collections.
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Shedding light on the dark side of firm lobbying
A firm's focus on customers may be diminished when it lobbies. Firm focus can be reoriented to customers, but doing so requires intentional, marketing-focused efforts.
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Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are activated by RA-induced Fgr expression
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Making negative opinions agreeable: Study finds social sharing happens in terms of support
Despite how toxic the social media sandbox can get, people more often share attitudes that are framed in terms of support instead of opposition, according to new research.
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Sharks, lies, and videotape: Scientists document problems with shark week
A new analysis by scientists shows that Shark Week, now in its 33rd year on the Discovery Channel, is deeply flawed in ways that undermine its goals, potentially harming both sharks and shark scientists. To document just how pervasive these issues are, a team of researchers performed a content and discourse analysis of more than 200 Shark Week episodes.
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"Noisy" gene expression may help improve stem cell therapies
As reported in the journal Science, Leor Weinberger and his team at Gladstone Institutes have discovered a pathway they named discordant transcription through repair (DiThR, pronounced "dither"). The DiThR pathway appears to boost the noisiness of gene expression in stem cells and enhance their ability to differentiate.
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Martian global dust storm ended winter early in the south
A dust storm that engulfed Mars in 2018 destroyed a vortex of cold air around the planet's south pole and brought an early spring to the hemisphere. By contrast, the storm caused only minor distortions to the polar vortex in the northern hemisphere and no dramatic seasonal changes.
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