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Blood-based biomarkers may predict HIV remission after stopping antiretroviral therapy

Eurekalert - Jun 29 2021 - 00:06
New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure. Wistar scientists have identified metabolic and glycomic signatures in the blood of a rare population of HIV-infected individuals who can naturally sustain viral suppression after ART cessation, known as post-treatment controllers.
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A step forward for IVF patients with predicted poor response to treatment

Eurekalert - Jun 29 2021 - 00:06
Fertility patients who have a poor response to ovarian stimulation represent a stubborn challenge in IVF. Clinical guidelines indicate that increasing the drug dose for stimulation or applying any of several adjunct therapies are of little benefit. A study assessing two cycles of ovarian stimulation and two egg collections in the same menstrual cycle may yet provide a real advance for predicted poor responders in IVF.
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How humans brought change to a tropical paradise

Eurekalert - Jun 29 2021 - 00:06
After centuries of human impact on the world's ecosystems, a new study from Flinders University details an example of how a common native bee species has flourished since the very first land clearances by humans on Fiji. In a new paper in Molecular Ecology, research led by Flinders University explores a link between the expansion of Homalictus fijiensis, a common bee, which has increased its spread on the main island Viti Levu alongside advancing land clearance and the introduction of new plants and weeds.
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University of Surrey and partners highlight the importance of lived experience provided by prisoners

Eurekalert - Jun 29 2021 - 00:06
In a paper published by Research Involvement and Engagement, the University of Surrey and its partners highlight the importance and value of 'lived experience' that only people in prison can provide to shape meaningful research and policy decisions.
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Researchers discover unique 'spider web' mechanism that traps, kills viruses

Eurekalert - Jun 29 2021 - 00:06
Immunologists at McMaster University have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2, the virus responsible for COVID-19.
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In a dish, a mouse, crafted from stem cells, begins to form

Eurekalert - Jun 29 2021 - 00:06
New advances in stem cell research will help scientists battle diseases, develop drugs and, eventually, grow organs for transplant.
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Personal networks are associated with clean cooking fuel adoption in rural South India

Eurekalert - Jun 29 2021 - 00:06
Government and public health experts in India have tried to convince poor households to shift to 'clean cooking' technology to reduce the use of wood, charcoal, and other traditional fuels. But in a country where household air pollution claims 600,000 lives per year, the shift has been slow. A new study led by Boston College researchers finds that personal networks play a significant role in whether rural poor households adopt cleaner fuels.
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Oregon State graduate student sheds light on better way to study reputedly secretive toad

Eurekalert - Jun 29 2021 - 00:06
CORVALLIS, Ore. - Research by a graduate student in Oregon State University's College of Science has upended the conventional wisdom that for a century has incorrectly guided the study of a toad listed as endangered in part of its range.
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Making seawater drinkable in minutes

Eurekalert - Jun 29 2021 - 00:06
A research team in Korea Institute of Civil Engineering and Building Technology (KICT) has developed co-axial electrospun nanofiber membranes fabricated by an alternative nanotechnology, which is electrospinning. This new desalination technology shows it has the potential to help solve the world's freshwater shortage. The developed technology can prevent wetting issues and also improve the long-term stability in membrane distillation process.
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Young adult cancer survivors reluctant to get COVID vaccines

Eurekalert - Jun 29 2021 - 00:06
A new paper in JNCI Cancer Spectrum indicates that many survivors of adolescent and young adult cancers hesitate to obtain COVID-19 vaccinations.
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Study sheds light on persistent racial disparities in prostate cancer care in the United States

Eurekalert - Jun 29 2021 - 00:06
Black men most likely to benefit from advanced prostate cancer therapies are 11% less likely to get them than non-Black men.
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Hotter, more frequent droughts threaten California's iconic blue oak woodlands

Eurekalert - Jun 29 2021 - 00:06
California's old-growth blue oak woodlands are dying off, shows a new study by the open access publisher Frontiers. The authors use a new approach to show that heat, drought and wildfires are the all contributing to the loss and deterioration of these native ecosystems. The study focuses on the extreme drought of 2012-2016, but suggests that these conditions will become more frequent in the future.
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How two California hospitals prevented the spread of a deadly fungal infection during the pandemic

Eurekalert - Jun 29 2021 - 00:06
In the midst of the COVID-19 pandemic, infection preventionists at two Southern California hospitals took extreme measures to stop the spread of a deadly fungus that has emerged in the U.S. and around the world. The two will detail their proactive responses in oral presentations today at the Association for Professionals in Infection Control and Epidemiology's (APIC's), 48th Annual Conference.
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Microfilter device capable of detecting trace amounts of cancer cells in one mL of blood

Eurekalert - Jun 28 2021 - 00:06
A microfilter device that can easily separate and capture trace amounts of cancer cells in blood has been developed by a Kumamoto University research group. The palm-sized device is expected to contribute to the development of new cancer diagnostic technologies based on cancer cells in the blood, such as early detection by blood test, postoperative management, and recurrence monitoring.
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NTU develops rapid malaria test kit that could aid diagnosis in developing countries

Eurekalert - Jun 28 2021 - 00:06
A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has developed a test kit for malaria that delivers results in 30 minutes. The kit could facilitate the diagnosis of malaria in the field, as the equipment needed is anticipated to be lightweight, easy-to-use, and able to detect the disease in its early stages.
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COVID-19 news from Annals of Internal Medicine

Eurekalert - Jun 28 2021 - 00:06
Members of the ACTIV (Accelerating COVID-19 Therapeutic Interventions and Vaccines) workgroup, a partnership of experts representing government, industry, and academia, describe how nine master protocols for evaluating therapeutic agents for COVID-19 were designed, developed, and launched, and lessons learned that may be useful in meeting the challenges of a future pandemic. Their commentary is published in Annals of Internal Medicine.
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Key mutations in Alpha variant enable SARS-CoV-2 to overcome evolutionary weak points

Eurekalert - Jun 28 2021 - 00:06
One of the key mutations seen in the 'Alpha variant' of SARS-CoV-2 - the deletion of two amino acids, H69/V70 - enables the virus to overcome chinks in its armour as it evolves, say an international team of scientists.
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The Lancet Inf. Dis.: Coronavac COVID-19 vaccine safe in children and adolescents and triggers antibodies

Eurekalert - Jun 28 2021 - 00:06
Two doses of CoronaVac are safe and provoke a strong antibody response among children and adolescents aged 3-17 years, according to a randomised controlled trial of 550 young people published in The Lancet Infectious Diseases journal.
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Evidence against physically punishing kids is clear, researchers say

Eurekalert - Jun 28 2021 - 00:06
A conclusive narrative review has found physical punishment of children is not effective in preventing child behavior problems or promoting positive outcomes and instead predicts increases in behavior problems and other poor outcomes over time. The study by an international group of scientists including a researcher from The University of Texas at Austin was published today in The Lancet.
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Sleep-deprived individuals less forthcoming with information about criminal history

Eurekalert - Jun 28 2021 - 00:06
During the course of a criminal investigation, it is common for investigators to interview individuals who've had little sleep. While unavoidable in some cases, a new study found sleep disruption or deprivation may limit the amount of information provided during an interview.
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