Science 2.0
Using Cholera To Battle Colorectal Cancer
Colorectal cancer, cancer of the colon and rectum, is the third most common form of cancer in the world and has the second highest mortality rate. When caught early enough, it is usually treated with surgery, radiation or chemotherapy, methods that can have significant side effects.
A new study highlights a fourth way, one the researchers hope could have fewer side effects. They found that a purified toxin secreted by cholera bacteria can slow the growth of colorectal cancer and has not shown any side effects. It worked by changing the immune microenvironment in tumors.
A new study highlights a fourth way, one the researchers hope could have fewer side effects. They found that a purified toxin secreted by cholera bacteria can slow the growth of colorectal cancer and has not shown any side effects. It worked by changing the immune microenvironment in tumors.
Categories: Science 2.0
E. Coli Linked To Diabetic Foot Infections Gets Worldwide Analysis
Diabetic foot infections are a serious complications of diabetes and a leading cause of lower-limb amputation but little is known about the specific pathogens involved in these chronic foot infections, particularly E. coli, despite its frequent detection in clinical samples.
A new genomic characterization of E. coli strains isolated directly from diabetic foot ulcers across multiple continents may help explain why some infections become difficult to treat and lead to severe, even life-threatening, outcomes. The team analyzed whole-genome sequences from 42 E. coli strains isolated from infected diabetic foot ulcers in patients from Europe, Africa, Asia, and the Americas and sequenced the complete DNA of each bacterial strain.
A new genomic characterization of E. coli strains isolated directly from diabetic foot ulcers across multiple continents may help explain why some infections become difficult to treat and lead to severe, even life-threatening, outcomes. The team analyzed whole-genome sequences from 42 E. coli strains isolated from infected diabetic foot ulcers in patients from Europe, Africa, Asia, and the Americas and sequenced the complete DNA of each bacterial strain.
Categories: Science 2.0