Melanoma, an aggressive form of skin cancer, has been increasing in incidence in adults over the past 40 years.
Pediatric melanoma is rare (5 or 6 children per million) but some studies indicate that incidence has been increasing. A new study in The Journal of Pediatrics found that is not so, and the incidence of pediatric melanoma in the United States decreased from 2004-2010.
A newly developed assay may help investigators identify novel drug candidates to protect kidney cells and prevent or treat chronic kidney disease (CKD).
CKD affects more than 13% of adults in the United States, with diabetes, hypertension and atherosclerosis being common risk factors. Most patients rely on antihypertensive medications for treatment, and there are no therapies available that directly and specifically target the kidney.
A team led by Vineet Gupta, PhD and Jochen Reiser, MD, PhD (Rush University Medical Center) has now developed a system that can be used to identify novel drug candidates that protect the function of kidney podocytes, cells that are critical for filtering the blood. Damage to these cells is a hallmark of CKD.
In the most famous versions of Richard III, written by William Shakespeare, the last Plantagenet king was physically and mentally deformed.
But the public probably did not know what, and if they did, they wisely never mentioned it. A king busy fighting the War of the Roses could easily hide a deformity. Dr. Mary Ann Lund, of the University of Leicester's School of English argues that Richard's body image in life was carefully controlled and he probably kept any signs of his scoliosis hidden outside of the royal household - but after his death at the Battle of Bosworth, he was carried to Leicester and exhibited before being buried and it wasn't a secret after that.
Since it was revealed that Andreas Lubitz – the co-pilot who purposefully crashed Germanwings Flight 9525, killing 150 people – had been treated for psychiatric illness, a debate has ensued over whether privacy laws regarding medical records should be less strict when it comes to professions that carry special responsibilities.
It has been widely argued that Germany’s privacy laws were to blame for the tragedy. The Times, for example, headlined an article: “German obsession with privacy let killer pilot fly.” Similarly, another article published in TIME said “German privacy laws let pilot ‘hide’ his illness from employers.”-->
E-cigarettes, battery-powered devices that heat a liquid nicotine solution, have been sold in the United States since 2007 and are marketed as an option to help smokers kick the habit. Instead of a nicotine patch or chewing gum, e-cigarette users inhale the vapor.
It's obviously safer than smoking but anti-cigarette advocates in the United States of America are also against this 'vaping' because of the presence of cigarette companies as investors. Originally, smoking awareness was to get people to get rid of smoking but a campaign against a smoking cessation product means it is more of a desire to get rid of certain companies.
A systematic review of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a particularly aggressive form of non-Hodgkin's lymphoma, shows that many cases of the disease are driven by alterations in the JAK/STAT3 cell signaling pathway. The study also demonstrates, in mice implanted with human-derived ALCL tumors, that the disease can be inhibited by compounds that target this pathway, raising hopes that more effective treatments might soon be developed.
A team of astronomers studied the simultaneous collision of four galaxies in the galaxy cluster Abell 3827 and could trace out where the mass lies within the system and compare the distribution of the dark matter with the positions of the luminous galaxies.
Although dark matter cannot be seen, the team could deduce its location using a technique called gravitational lensing. The collision happened to take place directly in front of a much more distant, unrelated source. The mass of dark matter around the colliding galaxies severely distorted spacetime, deviating the path of light rays coming from the distant background galaxy -- and distorting its image into characteristic arc shapes.
Climate change and the loss of biodiversity are two of the greatest environmental issues of our time. Is it possible to address both of those problems at once?
In Australia, farmers and landholders will this week be able to apply for payments through the Federal government’s A$2.55 billion Emissions Reduction Fund. Bidders can request funding for projects that reduce emissions using agreed methods, which include approaches relevant to the transport, waste and mining sectors, as well as the land sector: for example, by managing or restoring forests.-->
Shaved heads have come in and out of fashion over the past few decades, but some people don’t have the option of allowing their locks to grow.
Thankfully, for those who do suffer from hair loss, or alopecia, help may be at hand. Somewhat counter-intuitively an effective treatment for baldness may come from plucking a certain number of hairs – in a specific formation – from the scalp.