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How do developing spinal cords choose 'heads' or 'tails'?

Eurekalert - Jun 21 2021 - 00:06
Scientists at Gladstone Institutes have created an organoid--a three-dimensional cluster of cells grown in the lab--that mimics the earliest developmental steps of the nervous system in embryos. The organoid is the first to show how human spinal cord cells become oriented in an embryo, and could shed light on how environmental exposures or toxins can make this process go awry, causing early miscarriages and birth defects.
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AGS publishes updated AGS Minimum Geriatrics Competencies for Graduating Medical Students

Eurekalert - Jun 21 2021 - 00:06
The American Geriatrics Society (AGS) has published an updated version of the AGS Minimum Geriatrics Competencies for Graduating Medical Students, which were created to ensure that medical school graduates across the US are prepared to provide high-quality care for us all as we age. A workgroup of American Geriatrics Society leaders updated the original competencies using a modified Delphi method to reach a group consensus based on expert and stakeholder input and a literature review.
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Landmark field trials show potential of gene-editing

Eurekalert - Jun 21 2021 - 00:06
Field trials investigating healthy compounds in agronomically important brassica crops have underlined the "immense potential" of gene editing technology, say researchers.
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Study examines how breast implant surfaces affect immune response

Eurekalert - Jun 21 2021 - 00:06
Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of silicone breast implants influences adverse side effects.
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Study: Electronic monitoring failed to reduce recidivism for girls in juvenile justice system

Eurekalert - Jun 21 2021 - 00:06
In recent years, many juvenile courts have adopted in-home detention with electronic monitoring tethers as an alternative to institutional incarceration. A new study examined whether this approach reduces recidivism among girls involved in the juvenile justice system. The study found that tethers failed to reduce reoffending among the girls; in fact, they may be harmful because in-home detention limits girls' access to treatment programs.
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Ben-Gurion U. scientists invent an artificial nose for continuous bacterial monitoring

Eurekalert - Jun 21 2021 - 00:06
'We invented an artificial nose based on unique carbon nanoparticles ('carbon dots') capable of sensing gas molecules and detecting bacteria through the volatile metabolites the emit into the air,' says lead researcher Professor Raz Jelinek, BGU vice president for Research & Development, member of the BGU Department of Chemistry and the Ilse Katz Institute for Nanoscale Science and Technology, and the incumbent of the Carole and Barry Kaye Chair in Applied Science.
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Modeling a circular economy for electronic waste

Eurekalert - Jun 21 2021 - 00:06
New research from the Hypothetical Materials Lab at the University of Pittsburgh Swanson School of Engineering develops a framework to understand the choices an electronic waste recycler has to make and the role that digital fraud prevention could have in preventing dishonest recycling practices.
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New method for molecular functionalization of surfaces

Eurekalert - Jun 21 2021 - 00:06
An interdisciplinary team of researchers has succeeded in depositing nitrogen-containing organic molecules as a highly ordered layer on silicon. This opens up new perspectives for the development of more powerful semiconductor materials, which can be used, for example, in computers, photovoltaics or sensor technology.
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Lead from leaded petrol persists in London air despite '90s ban

Eurekalert - Jun 21 2021 - 00:06
Research from Imperial College London has found that lead from leaded petrol persists in London's air despite its ban in 1999.
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Butterflies cross the Sahara in longest-known insect migration

Eurekalert - Jun 21 2021 - 00:06
Wetter conditions in Sub-Saharan and North Africa at certain times of year can result in hundreds of times more Painted Lady butterflies making the 14,000km round trip to Europe. Findings improve understanding of how insects move to other countries, including pests that destroy crops and disease-carrying species like mosquitoes.
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Changes in farming practices could reduce greenhouse gas emissions by 70% by 2036

Eurekalert - Jun 21 2021 - 00:06
Team used Argonne's GREET model to simulate changes, predict outcomes.
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Women who lose close elections are just as likely to run again as men

Eurekalert - Jun 21 2021 - 00:06
New research finds women who lose local or state elections are just as likely to run for office again as men, suggesting the recent surge in women candidates may have a long-term impact on women's political representation. Political scientists Rachel Bernhard of UC-Davis and Justin de Benedictis-Kessner of Harvard Kennedy School found no evidence of a gender gap in candidates' responses to losing a race. Their study was published today in the Proceedings of the National Academy of Sciences.
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The same cell type can help or hinder kidney repair after acute injury

Eurekalert - Jun 21 2021 - 00:06
USC Stem Cell has identified a type of injured cell that might contribute to the transition from an acute kidney injury to chronic kidney disease. When an injury caused proximal tubule cells (PTCs) to die, surviving ones multiplied to repair the injury. But after function was restored, some PTCs which failed to repair normally appeared at the injury site. These damaged cells showed activity implicated in processes associated with progression to chronic disease.
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Exposure to pollutants, increased free-radical damage speeds up aging

Eurekalert - Jun 21 2021 - 00:06
A new study from West Virginia University researcher Eric E. Kelley -- in collaboration with the University of Minnesota -- suggests that unrepaired DNA damage can increase the speed of aging.
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New method developed to detect and adjust population structure in genetic summary data

Eurekalert - Jun 21 2021 - 00:06
University of Colorado Denver researchers announced the development of a new method to increase the utility and equity of large genetic databases.
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SARS-CoV-2 infections may trigger antibody responses against multiple virus proteins

Eurekalert - Jun 21 2021 - 00:06
All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and nucleocapsid proteins. A study published in PLOS Biology by Anna Heffron, Irene Ong and colleagues at the University of Wisconsin-Madison, USA, suggests that immune responses may develop against other proteins produced by the SARS-CoV-2 virus.
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Health disadvantages of LGB communities increase among younger generations

Eurekalert - Jun 21 2021 - 00:06
The first population-based national study comparing mental and physical health of lesbian, gay and bisexual Americans to their straight counterparts revealed that younger generations are worse off than Baby Boomers.
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Universal mechanism of regulation in plant cells discovered

Eurekalert - Jun 21 2021 - 00:06
This involves the DYW deaminase domain of what is referred to as the RNA editosome. The DYW domain alters messenger RNA nucleotides in chloroplasts and mitochondria and contains a zinc ion whose activity is controlled by a very unusual mechanism. The team has now described this mechanism in detail for the first time. Their study is considered a breakthrough in the field of plant molecular biology and has far-reaching implications for bioengineering.
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Common perovskite superfluoresces at high temperatures

Eurekalert - Jun 21 2021 - 00:06
A commonly studied perovskite can superfluoresce at temperatures that are practical to achieve and at timescales long enough to make it potentially useful in quantum computing applications.
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Profiling gene expression in plant embryos one nucleus at a time

Eurekalert - Jun 21 2021 - 00:06
The first plant embryo gene expression atlas at the single cell level was developed by a team of researchers at GMI - Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences. The work, published in the journal Development, is a milestone on the way to uncovering the molecular mechanisms that determine how the most fundamental plant cell-types are established at the beginning of life.
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