Feed aggregator

The story of efforts to conserve the endangered oribi in South Africa represent a diaspora of issues as varied as the people who live there.

A detailed molecular analysis of tissue from the brains of individuals who died of COVID-19 reveals extensive signs of inflammation and neurodegeneration, but no sign of the virus that causes the disease.

Years before they are diagnosed, persons with multiple sclerosis (MS) make significantly more visits to doctors and hospitals than others. Specialists have recently discussed whether this might represent a preliminary phase of MS - known as a prodrome. A research team at the Technical University of Munich (TUM) has now published results of a study suggesting that, in many cases, the complaints may relate to unrecognized early clinical MS events.

The nucleus is much more than a storage compartment for chromosomes: It also contains the complex machinery producing transcripts of the genes that are currently needed and releases them into the cell body. Some of the proteins involved herein are not evenly distributed in the nucleus, but cluster at specific sites. A study led by the University of Bonn (Germany) now shows how these "flash mobs" are regulated. The results are published in "Cell Reports".

"Workforce issues are the most significant challenges facing the long-term care industry," states the opening editorial of a new special issue of The Gerontologist titled "Workforce Issues in Long-Term Care."

New research published in the Journal of Medicinal Food suggests eating prunes each day can improve risk factors for cardiovascular disease (CVD) including raising antioxidant capacity and reducing inflammation among healthy, postmenopausal women.

Pancreatic cancer cells typically rely on a mutant version of the KRAS protein to proliferate. These cancer cells can also survive losing KRAS by activating alternative growth pathways. CSHL scientists discovered a new interaction between mutant KRAS and a protein complex called RSK1/NF1 that may be the source of this adaptive resistance.

Results from a new study show that many Americans remain fiercely loyal to their like-minded communities, even when their health is on the line -- an important lesson for future pandemics.

Lung cancer remains the leading cause of cancer-related deaths. Non-small cell lung cancer (NSCLC) accounts for 80-85% cases of lung cancer and when diagnosed early, has a five-year survival rate of 50-80%. Black patients have lower overall incidence of NSCLC than white patients, but are more likely to be diagnosed at later stages. They also are less likely to receive surgery for early-stage cancer.

A research team from Wayne State University's Institute of Gerontology recently published the results of a three-year study of cognitive changes in older adults who complained that their cognitive ability was worsening though clinical assessments showed no impairments. The MRI studies showed significant changes in functional connectivity in two areas of the brain.

An enzyme found in fat tissue in the centre of our bones helps control the production of new bone and fat cells.

University of Cincinnati researchers have developed a blueprint of the protein anti-Müllerian hormone hormone helps form male reproductive organs and in females regulates follicle development and ovulation in the ovaries. That knowledge could help researchers treating female infertility.

Antibody-drug conjugates developed are found to attack not only targeted tumor cells but also nontargeted 'bystanders.'

UC researchers developed a novel system to analyze ancient plant DNA in the sediment of Tikal's temple and palace reservoirs to identify more than 30 species of trees, grasses, vines and flowering plants that lived along its banks more than 1,000 years ago. Their findings paint a picture of a lush, wild oasis in the ancient Maya city.

Researchers have identified a combination of biological markers in patients with dengue that could predict whether they go on to develop moderate to severe disease.

Few animals can regenerate their spinal cord after an injury. The axolotl can mobilise stem cells in its spinal cord to regrow the lost tissue. An international team of scientists from Argentinas National Scientific and Technical Research Council (CONICET), the Research Institute of Molecular Pathology (IMP) in Austria, and the Technische Universitaet Dresden in Germany investigated the early stages of this process. Their findings are now published on the online platform eLife.

Solar steam generation has emerged as a promising renewable energy technology for water harvesting, desalination, and purification that could benefit people who need it most in remote communities, disaster-relief areas, and developing nations. In Applied Physics Letters, researchers inspired by mangrove trees thriving along coastlines developed a synthetic tree to enhance SSG, replacing capillary action with transpiration, the process of water movement through a plant and its evaporation from leaves, stems, and flowers.

The mystery of an exotic kind of supraconductivity has been solved -- by showing that it just does not exist. An effect, which has been celebrated since the 1990s has now been shown to be standard superconductivity. Still, this realization leads to important new ideas.

A team of scientists from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now discovered that the odorant receptor OR5K1 is specialized to recognize pyrazines in both humans and domesticated animals. These are volatile substances that contribute to the typical odor of many vegetables or are formed when food is heated. In addition, pyrazines also play a role as signaling substances in intra- or interspecific communication.

Most of us have genetic variations that increase the risk of medicinal products not being effective. In order to provide a more effective treatment with fewer side effects, we need to analyze more of these genetic variations. This will provide us with more precise knowledge about how the individual patient reacts to medicinal products. A new research result from Aarhus University shows that.