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Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.

COVID-19 complicated patient care in a range of ways, from increased incidence of heart attacks to decreased cancer screenings. The virus also caused a six-fold increase in the risk of complications and death among trauma patients, according to new research.

Support recently reported findings of clinical benefit when relacorilant is added to paclitaxel-containing therapy in patients with ovarian and pancreatic cancers and provide a new rationale for combining relacorilant with additional cytotoxic agents.

To tackle this issue, a research team led by Dr. Ju Hee Ryu of the Center for Theragnosis at the Korea Institute of Science and Technology (KIST) has developed an anti-cancer prodrug that can improve anti-cancer immunotherapy by reacting only with cancer cells, thereby minimizing the toxicity to normal cells, including immune cells, and boosting patient immunity.

In CTP class A patients, IGF/CTP score B was associated with shorter PFS and OS

The P142 panel of metrics successfully predicted cancer progression status in patients with some, but not all cancer types analyzed.

By incorporating cell composition into their regression model, they identified 3,193 differentially expressed genes, of which 556 were deemed novel.

A study in more than 200,000 individuals has found that patients with heart failure are more likely to develop cancer compared to their peers without heart failure. The research is presented today at Heart Failure 2021, an online scientific congress of the European Society of Cardiology (ESC), and published in ESC Heart Failure, a journal of the ESC.

Designed initially for entertainment purposes, escape rooms are proving their value as medical training tools as demonstrated by the Central Texas Veterans Health Care System. Staff there have used the concept for a flu pandemic escape room and is reporting increased staff handwashing and acceptance of flu vaccines as a result.

Nearly a quarter of parents have suspected their child might be delayed in their development, a new national poll finds - but they may not always share these concerns with a doctor.

Saturated fatty acid levels unexpectedly rise in the brain during memory formation, according to University of Queensland researchers.

USTC realized two-photon quantum interference in the structure of valley-dependent topological insulators based on the valley Hall effect.

With the rapid development of biomedical technology, the replacement of human skeletal diseases through human implants has become an application market with high technical content and huge benefits. In order to quickly customize human implants with complex structures, Chinese scientists use 3D printing technology to prepare Ti-Mo alloy human implants, and then adjust the microstructure and performance of the human implants through subsequent heat treatment, so as to obtain human implant products with excellent compatibility.

The research team from Life Science and Medicine of University of Science and Technology of China, realized lysosome typing based on single lysosome metabonomic information for the first time by stablishing a single lysosome metabonomic mass spectrometry detection technology.

Oceans viromes remain poorly understood and little is known about the ecological factors driving aquatic RNA virus evolution. In the study, reseaechers used a meta-transcriptomics approach to characterize the viromes of 58 marine invertebrates species across three seas, demonstrated the hidden diversity of marine invertebrates RNA viruses.

Surface-enhanced Raman scattering (SERS) permits multidisciplinary trace analyses and the potential detection of single molecules. Shi Bai and Koji Sugioka from RIKEN report a comprehensive review of recent progress in strategies for the fabrication of highly sensitive SERS substrates. Femtosecond laser-based techniques are discussed as a versatile tool for the fabrication of SERS substrates. Several approaches are highlighted for enhancing the performance of SERS sensing devices, and real-time sensing and biological applications are reviewed.

The continuous weakening of global land surface wind speed (stilling) has seriously affected the ecological environment and social economy, especially restricted the sustainable development of the wind energy industry. A recent study systematically answered the question of whether the surface wind speed in China is still weakening.

Most realized 3D architectures are composed of only a single polymeric material. Here, we review 3D printing of multi-materials on the nano- and microscale. We start with material properties that have been realized, using multi-photon photoresists. Next, we review manual and automated processes achieving dissimilar material properties in a single 3D structure by sequentially photo-exposing multiple photoresists and by controlled stimuli of a single photoresist. Instructive examples from biology, optics, mechanics, and electronics are discussed.

A large number of articles have been published using resting-state functional magnetic resonance imaging for clinical research, and almost all the results survived multiple comparisons correction, a standard procedure performed to reduce false positive rates. Now the researchers from more than 20 worldwide groups have found that in individual studies with small sample sizes, a smaller p value reduced true positive effect and did not save the reproducibility of true effects.

Under the background of global warming and the increasing impact of human activities, the phenomenon of coral bleaching is becoming more and more serious. Scleractinian coral as mixotrophic organisms, but it is unclear about the impact of trophic flexibility on their environmental adaptability. Recent studies have revealed that coral could enhance its environmental adaptability by adjusting trophic status. This discovery was reported in the cover article of "SCIENCE CHINA: Earth Sciences", Issue 6, 2021.