Brain

Cell of origin for brain tumors may predict response to therapy

For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma. This distinction explains why oligodendroglioma is more responsive to therapy than other brain tumors such as glioblastoma multiforme.

UCI researchers find novel memory-enhancing mechanism in brain

Irvine, Calif., Dec. 14, 2010 — UC Irvine researchers have identified a novel mechanism in the brain that boosts memory.

In collaboration with scientists at Germany's University of Munster, the UCI team found that a small protein called neuropeptide S can strengthen and prolong memories of everything from negative events to simple objects.

High-tech software, umanned planes allow scientists to keep tabs on Arctic seals

A novel project using cameras mounted on unmanned aircraft flying over the Arctic is serving double duty by assessing the characteristics of declining sea ice and using the same aerial photos to pinpoint seals that have hauled up on ice floes.

Unique case study on Alzheimer's disease

A case study from the Swedish medical university Karolinska Institutet sheds light on the pathological course of Alzheimer's disease. The brain of the first Alzheimer's patient to display amyloids demonstrable with a PET scanner has been studied, both during progression of the disease and after death.

Transcription factor clears protein clumps in Huntington's mice models

Over expressing a transcription factor that promotes the increase in number of mitochondria greatly improves the neurological function of transgenic mice models for Huntington's disease (HD), researchers today told the American Society of Cell Biology's 50th Annual Meeting in Philadelphia.

Albert La Spada, M.D., Ph.D., and colleagues at the UC San Diego (UCSD) explained that over expression of the transcription factor results in a substantial clearing of the mutant protein aggregates in the brains of the mice models for HD.

Attempting to predict epileptic seizure

Washington, D.C. (December 14, 2010) -- While the causes of epileptic seizures continue to confound brain researchers, scientists have been exploring how changes in the coordinated activity of brain networks, as monitored through electrodes, might help predict impending seizures. A report in the American Institute of Physics' journal CHAOS offers new insight into this possibility.

Biracial and passing -- as black

WASHINGTON, DC, December 8, 2010 — In a country with Jim Crow segregation laws and the "one-drop rule" determining who was black and therefore where and what a person was permitted to be, it's easy to see why those who plausibly could, might pass as white. But new research published in the December issue of Social Psychology Quarterly shows that black-white biracial adults now exercise considerable control over how they identify and the authors find "a striking reverse pattern of passing today," with a majority of survey respondents reporting that they pass as black.

Study finds prayer can help handle harmful emotions

MADISON — Those who choose to pray find personalized comfort during hard times, according to a University of Wisconsin-Madison sociologist.

The 75 percent of Americans who pray on a weekly basis do so to manage a range of negative situations and emotions — illness, sadness, trauma and anger — but just how they find relief has gone unconsidered by researchers.

Study finds prayer can help handle harmful emotions

WASHINGTON, DC, December 13, 2010 — Those who choose to pray find personalized comfort during hard times, according to a University of Wisconsin-Madison sociologist.

The 75 percent of Americans who pray on a weekly basis do so to manage a range of negative situations and emotions — illness, sadness, trauma and anger — but just how they find relief has gone unconsidered by researchers.

Parkinson's disparities

Baltimore, MD – Dec. 13, 2010. African American patients and those with lower socioeconomic status have more advanced disease and greater disability when they seek treatment from Parkinson's disease specialists, according to a study from the University of Maryland School of Medicine. The researchers found that race, education and income were each significant and independent factors in determining a patient's level of disability. The disparities in health care are associated with greater disease severity and earlier loss of independence.

Strength training for seniors provides cognitive function, economic benefits: VCH-UBC study

A one-year follow-up study on seniors who participated in a strength training exercise program shows sustained cognitive benefits as well as savings for the healthcare system. The research, conducted at the Centre for Hip Health and Mobility at Vancouver Coastal Health and the University of British Columbia, is published today in the Archives of Internal Medicine.

Protein restores learning, memory in Alzheimer's mouse model

Protein restores learning, memory in Alzheimer's mouse model

Scientist shows link between diet and onset of mental illness

WEST LAFAYETTE, Ind. - Changes in diet have been linked to a reduction of abnormal behaviors in mentally ill people or animals, but a Purdue University study shows that diet might also trigger the onset of mental illness in the first place.

U-M researchers discover way to block neurodegeneration in an adult form of Fragile X syndrome

Ann Arbor, Mich.— Expression of a toxic RNA that leads to Fragile X Tremor Ataxia Syndrome is modifiable by genetic or pharmacologic means, according to new research from U-M Medical School scientists.

In the study published online today in the journal Public Library Of Science Genetics, U-M's Peter K. Todd, M.D., Ph.D., led a team of researchers who examined the expression of a toxic messenger RNA (mRNA) seen in the brains of those afflicted with the syndrome.

Recovering from job loss: Most report few long-term psychological effects, study finds

WASHINGTON – Losing a job is a profoundly distressing experience, but the unemployed may be more resilient than previously believed – the vast majority eventually end up as satisfied with life as they were before they lost their jobs, according to a new analysis published by the American Psychological Association.