Body

Hck protein opens the door to new HIV drug possibilities

PITTSBURGH, Oct. 13 – While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease.

Important defense against stomach ulcer bacterium identified

A special protein in the lining of the stomach has been shown to be an important part of the body's defense against the stomach ulcer bacterium Helicobacter pylori in a new study from the Sahlgrenska Academy at the University of Gothenburg. The discovery may explain why the bacterium makes some people more ill than others.

The study was conducted in collaboration with researchers at universities in Brisbane and Melbourne and has been published in the scientific journal PLoS Pathogens.

Impaired fetal growth increases risk of asthma

[PRESS RELEASE, 12 October 2009] A new study from the medical university Karolinska Institutet in Stockholm shows that children born with low birth weight are at a higher risk of developing asthma later in life. The study, which is published in the journal Pediatrics, is based on data on the incidence of asthma in 10,918 twins from the Swedish Twin Registry.

Premium auto tech and cow dung point to new high tech disease diagnosis

Research at the University of Warwick have taken high tech gas sensors normally used to test components for premium cars and applied the same techniques to human blood, human urine, and even cow dung samples from local cow pats. The results could lead to a new high tech medical tool that could provide a fast diagnosis for some of the most difficult gastrointestinal illnesses and metabolic diseases

Setting sail in an ecological 'Earthship'

Could sustainable architecture address pollution, climate change and resource depletion by helping us build self-sufficient, off-grid, housing from "waste", including vehicle tires and metal drinks containers? That's the question researchers at the University of South Australia hope to answer in the International Journal of Sustainable Design.

'Junk RNA'? A myth--unless disease prevention is useless

PITTSBURGH, Oct. 12 – Tiny strands of RNA previously dismissed as cellular junk are actually very stable molecules that may play significant roles in cellular processes, according to researchers at the University of Pittsburgh School of Medicine and the University of Pittsburgh Cancer Institute (UPCI). The findings, published last week in the online version of the Journal of Virology, represent the first examination of very small RNA products termed unusually small RNAs (usRNAs).

UF researchers find triggers in cells' transition from colitis to cancer

GAINESVILLE, Fla. -- University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer and how it might be prevented.

Scientists observed that cancer stem cells taken from the gastrointestinal system in patients with a chronic digestive disease called ulcerative colitis will transform into cancerous tumors in mice.

Singapore scientists discover widely sought molecular key to understanding p53 tumor suppressor gene

Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequences of nucleotides in the gene's DNA.

Their findings provide a missing piece about p53 gene repression that has eluded researchers investigating the master regulator, which undergoes mutations or deletions in over 50 percent of all cancers.

Blood ties -- younger generation more willing to donate blood

Youth may not bring wisdom but, according to a new study from Canada, it does bring generosity as young adults are found to be the most likely to donate blood. The research, published in BioMed Central's open access International Journal of Health Geographics, looked at what factors had an impact on donating blood.

New cancer gene discovered

A new cancer gene has been discovered by a research group at the Sahlgrenska Academy at the University of Gothenburg, Sweden. The gene causes an insidious form of glandular cancer usually in the head and neck and in women also in the breast. The discovery could lead to quicker and better diagnosis and more effective treatment.

The study is published today in the prestigious scientific journal Proceedings of the National Academy of Sciences (PNAS).

Canadian blood supply future uncertain as population ages: Study

The Canadian blood supply relies heavily on a small number of donors—with young adults donating at higher rates—which may prove problematic as the population ages, according to a new study from McMaster University.

The research, published in open access format in the International Journal of Health Geographics, examined what specific factors had an impact on blood donation in this country.

Dysfunctional protein dynamics behind neurological disease?

Researchers at Lund University, Sweden, have taken a snapshot of proteins changing shape, sticking together and creating structures that are believed to trigger deadly processes in the nervous system. The discovery opens the possibility of designing drugs for a devastating neurological disease, ALS.

Study questions need for routine intervention in patients with renovascular disease

WINSTON-SALEM, N.C. – Some invasive procedures that are becoming increasingly common as a first line of treatment for patients diagnosed with narrowed arteries in and around the kidneys may not be necessary, according to a new study by researchers at Wake Forest University Baptist Medical Center.

The 12-step path to white-collar crime

Adelphia Communications, Barings Bank, Enron, HealthSouth, HIH Insurance, Hollinger International, Tyco International, WorldCom/MCI, Xerox...the white collar crime list goes on. But, did the executives at these companies start out as criminals or did they head down the slippery slope to criminality one misplaced step at a time? According to research to be published in the International Journal of Business Governance and Ethics, there are twelve steps to white-collar crime.

Magnetic nanotags spot cancer in mice earlier than methods now in clinical use

Searching for biomarkers that can warn of diseases such as cancer while they are still in their earliest stage is likely to become far easier thanks to an innovative biosensor chip developed by Stanford University researchers.

The sensor is up to 1,000 times more sensitive than any technology now in clinical use, is accurate regardless of which bodily fluid is being analyzed and can detect biomarker proteins over a range of concentrations three times broader than any existing method, the researchers say.