Body

Women with increased levels of Müllerian inhibiting substance (MIS), best known for regulating in utero sexual differentiation in boys, may be at a greater risk for breast cancer, according to a new study published online October 9 in the .Journal of the National Cancer Institute.

SAN FRANCISCO - Women with a deleterious gene mutation are diagnosed with breast cancer six years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The University of Texas M. D. Anderson Cancer Center.

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.

HOUSTON - A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports this week in the journal Molecular Cell.

PHILADELPHIA (October 09, 2009) -- According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas.

Commonly used in agriculture and medicine, these chemical compounds were not previously known to act on the T1R3 receptor.

The secret lives of some of Africa's iconic carnivores, including big cats, are revealed in a new study in Animal Conservation, today.

The results shed light on how different habitats are used by some of Tanzania's most elusive meat eaters, such as the leopard.

Scientists from the Zoological Society of London (ZSL), the Wildlife Conservation Society (WCS) and the Tanzania Wildlife Research Institute (TAWIRI) carried out the largest survey of Tanzania's carnivores, using a novel approach making use of over 400 camera trap locations.

Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response to new cancer-fighting drugs. Published online in the Journal of Clinical Oncology, the study by Rom Leidner, MD, and colleagues report that ethnicity plays a significant role in non-small cell lung cancer (NSCLC) genetics and more personalized treatments may be beneficial to cancer patients.

October 9, 2009 - Shingu, Japan – An international group of scientists aboard the Deep-Sea Drilling Vessel CHIKYU, operated by the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) for the Integrated Ocean Drilling Program (IODP), return from a 40-day scientific expedition off the shore of the Kii Peninsula, Japan on Oct. 10, 2009. Expedition 322, called "Subduction Inputs" in the multi-stage project, conducted drilling, logging and sampling beneath the ocean floor to investigate input material that will be transported to the seismogenic zone by the plate subduction system.

(Boston) - Investigators from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System have shown, at 6 months in a small group of patients, that there is no difference in efficacy between Bevacizumab (Avastin) and Ranibizumab (Lucentis) for the treatment of age-related macular degeneration (AMD).

One hundred years ago, Kikunae Ikeda discovered the flavour-giving properties of glutamate, a non essential amino acid traditionally used to enhance the taste of many fermented or ripe foods, such as ripe tomatoes or cheese. New research now reveals that the tongue has a receptor that is exclusively activated by glutamate.

ANN ARBOR, Mich. – Patients who received refurbished pacemakers donated from Detroit area funeral homes survived without complications from the devices, according to a case series reported by the University of Michigan Cardiovascular Center.

The pacemakers were implanted in 12 patients at the University of Philippines- Philippine General Hospital who could not afford advanced cardiac care and were confined to their beds as they waited for a permanent pacemaker.

Women with breast cancer should be given high doses of vitamin D because a majority of them are likely to have low levels of vitamin D, which could contribute to decreased bone mass and greater risk of fractures, according to scientists at the University of Rochester Medical Center.

Scientists have found that the human liver fluke (Opisthorchis viverrini) contributes to the development of bile duct (liver) cancer by secreting granulin, a growth hormone that is known to cause uncontrolled growth of cells. Details are published October 9 in the open-access journal PLoS Pathogens.

New research published this week clips the wings of Archaeopteryx. First found in Germany in the 1860's and dating to 150 million years ago, Archaeopteryx has long been considered the iconic first bird. But microscopic imaging of bone structure published in PLoS One shows that this famously feathered fossil grew much slower than living birds and more like non-avian dinosaurs.