Body

DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access the required sections and genes? That requires organisation.

A recently published study shows that gut microbiota regulates the glutathione and amino acid metabolism of the host. Glutathione is a key antioxidant, found in every cell in our body. Deficiency of glutathione contributes to oxidative stress, which plays a major role in several lifestyle diseases.

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In a new look at the groundbreaking iPrEx trial for people at high risk of HIV infection, UC San Francisco researchers have identified strong evidence of efficacy for transgender women when PrEP, a two-drug antiretroviral used to prevent HIV, is used consistently.

San Diego, CA (Nov. 6, 2015) -- New research uncovers racial disparities in rates of living kidney donation and complications after donation. The findings will be presented at ASN Kidney Week 2015 Nov. 3-8 at the San Diego Convention Center in San Diego, CA.

SAN DIEGO--Thiazide, a popular diuretic for lowering high blood pressure, may not excrete salt as expected in patients with congestive heart failure and or dehydration and should be taken with caution, say researchers at the University of Cincinnati.

A study led by Manoocher Soleimani, MD, James F. Heady Professor of Medicine and associate chair of research in the Department of Internal Medicine at UC, looked at thiazide use in experimental mouse models and was presented today at a meeting of the American Society of Nephrology's Kidney Week activities in San Diego.

Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have uncovered new clues to how a molecular machine inside the cell acts as a gatekeeper, allowing some molecules to enter and exit the nucleus while keeping other molecules out.

San Diego, CA (Nov. 6, 2015) -- Adults with kidney failure can benefit from cadaveric kidney transplants from infants and toddlers when adult organs are unavailable, according to a study that will be presented at ASN Kidney Week 2015 Nov. 3-8 at the San Diego Convention Center in San Diego, CA.

San Diego, CA (Nov. 6, 2015) -- Traveling abroad to receive a kidney from a paid living donor at a commercial transplant center carries considerable risks, according to a study that will be presented at ASN Kidney Week 2015 Nov. 3-8 at the San Diego Convention Center in San Diego, CA.

Combining the investigative tools of genetics, transcriptomics, epigenetics and metabolomics, a Duke Medicine research team has identified a new molecular pathway involved in heart attacks and death from heart disease.

The researchers, publishing in the journal PLOS Genetics, found that stress on a component of cells called the endoplasmic reticulum (ER) is associated with risk of future heart events, and it can be detected in bits of molecular detritus circulating in the blood.

Hearing is made possible when hair bundles protruding from the tops of hair cells capture the energy of sound waves, converting them into electrical signals that stimulate the auditory nerve to the brain. These hair bundles are made up of individual hair-like projections, or stereocilia, which sway in unison with other stereocilia, and remain permanently with us throughout our lives. Extremely loud noise can force whipsaw motion of the stereocilia, causing them to be damaged and the resulting hearing loss to be permanent.

A rapid-detection Ebola test developed by international scientists including a University of Stirling, Scotland virologist has been deployed following a highly effective pilot project.

Dr Manfred Weidmann, from the University's School of Natural Sciences, was part of a Wellcome Trust project led by the Pasteur Institute of Dakar.

Job applicants who are cancer survivors are less likely to receive callbacks from potential retail employers than those who did not disclose their health history, according to a recent study by Rice University and Penn State University researchers.

Massive glaciers once covered an island in one of the Great Lakes, USA, leaving it largely devoid of life. Its subsequent recolonisation by insects triggered the curiosity of entomologist R. Edward DeWalt and graduate student Eric J. South of the Illinois Natural History Survey and Department of Entomology.

BOSTON -- Nov. 6, 2015 -- The Phoenix-based Translational Genomics Research Institute (TGen) will lead an international Stand Up To Cancer (SU2C) Dream Team of top cancer researchers in a $12 million effort to double the survival of patients with pancreatic cancer, the fourth leading cause of cancer death in the U.S.