Body

Safeguarding genome integrity through extraordinary DNA repair

DNA is under constant attack, from internal factors like free radicals and external ones like ionizing radiation. About 10 double-strand breaks – the kind that snap both backbones of the double helix – occur every time a human cell divides. To prevent not only gene mutations but broken chromosomes and chromosomal abnormalities known to cause cancer, infertility, and other diseases in humans, prompt, precise DNA repair is essential.

Discovery of relationship between proteins may impact development of cancer therapies

By identifying a surprising association of two intracellular proteins, University of Iowa researchers have laid the groundwork for the development of new therapies to treat B cell lymphomas and autoimmune disease.

More accurate diagnosis of Alzheimer's

A new study from the University of Gothenburg, Sweden, shows how analysing spinal fluid can help to detect Alzheimer's disease at an early stage. The researchers behind the study hope that their findings will contribute to a greater international breakthrough for this type of diagnostic method.

LA BioMed study finds 'thirdhand smoke' poses danger to unborn babies' lungs

LOS ANGELES—(April 19, 2011)—Stepping outside to smoke a cigarette may not be enough to protect the lungs and life of a pregnant woman's unborn child, according to a new study in the American Journal of Physiology.

Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find

DALLAS – April 19, 2011 – Curbing carbohydrates is more effective than cutting calories for individuals who want to quickly reduce the amount of fat in their liver, report UT Southwestern Medical Center researchers.

"What this study tells us is that if your doctor says that you need to reduce the amount of fat in your liver, you can do something within a month," said Dr. Jeffrey Browning, assistant professor of internal medicine at UT Southwestern and the study's lead author.

Sugar helping map new ground against deadly bug

A potential vaccine against bacteria that cause serious gastric disorders including stomach cancer may be a step closer following a pioneering study by a University of Guelph chemist.

In the first published study of its kind, a team led by Prof. Mario Monteiro, Department of Chemistry, found a carbohydrate-based antigen caused mice to develop antibodies against a common bacterium linked to gastric cancer.

"This is the first jab at a sugar-based vaccine against Helicobacter pylori," said Monteiro, who completed the study with former undergrad student Stacey Britton.

Mood swings of bipolar patients can be predicted, study shows

The future mood swings of people with bipolar disorder can be predicted by their current thoughts and behaviour, a study published today (Tuesday) has found.

Psychologists from the Universities of Manchester and Lancaster say their findings are important because they mean talking therapies, like cognitive behavioural therapy (CBT), could prove effective treatments for the condition.

BIDMC researchers recommend 'dual citizenship' on social media

BOSTON – With ubiquitous social media sites like Facebook and Twitter blurring private and professional lines, there is an increasing need for physicians to create a healthy distance between their work and home online identities, two Beth Israel Deaconess Medical Center physicians assert.

GOES-13 satellite animation shows US severe storms and tornado outbreak

The GOES-13 satellite captured images of the powerful weather system that triggered severe weather in the southern U.S. this weekend, and NASA created an animation to show its progression. GOES-13 satellite data showed the strong cold front as it moved eastward from Saturday through Monday and generated tornadoes before moving off-shore into the Atlantic Ocean. NASA's Aqua satellite also captured data from the system and took the temperature of the cold front's cloud tops and revealing severely cold temperatures of some of the thunderstorms.

New biomarker allows early detection of adverse prognosis after acute kidney injury

CINCINNATI – A new biomarker-based diagnostic test is more effective than the current best practice for early detection of adverse outcomes after acute kidney injury (AKI), which can be fatal for an estimated 50 percent of the critically ill patients who get the condition.

Dietary, lifestyle changes can significantly reduce triglycerides

Dietary and lifestyle changes significantly reduce elevated triglycerides (a type of blood fat) — which is associated with heart, blood vessel and other diseases — according to an American Heart Association scientific statement

Changes such as substituting healthy, unsaturated dietary fats for saturated ones, engaging in physical activity and losing excess weight can decrease triglycerides by 20 percent to 50 percent, according to the statement's authors. The statement is published in Circulation: Journal of the American Heart Association.

Do-not-resuscitate orders associated with poor surgical outcomes even for non-emergency procedures

Surgical patients with do-not-resuscitate (DNR) orders appear to be at higher risk for poor surgical outcomes, according to a report published online today by the Archives of Surgery, one of the JAMA/Archives journals. The study will appear in the August print issue of the journal.

Previous-day alcohol consumption appears to affect surgical skills on virtual reality simulator

Excessive alcohol consumption appears to be associated with changes in some surgical skills performed on virtual reality simulator testing the following day, according to a report in the April issue of Archives of Surgery, one of the JAMA/Archives journals.

Airway abnormalities appear uncommon in well-appearing babies with apparent life-threatening events

Airway abnormalities were uncommon among well-appearing infants hospitalized with apparent life-threatening events, and pediatric otolaryngology service was involved in their care only a small proportion of the time during five years after the episode, according to a report in the April issue of Archives of Otolaryngology – Head & Neck Surgery, one of the JAMA/Archives journals.

Too many relatives ruining your picnic? Be glad the flies don't invite their cousins

AMES, Iowa – When your family members gather at a picnic in your backyard, there may be 10 to 20 people -- maybe more -- enjoying your barbecue.

When flies visit your party, be glad they don't bring their entire family.

Houseflies have more than 152,000 cousins. And those are just the ones we know about.

An Iowa State University researcher is one of a team of scientists who have recently researched the fly family tree -- one of the most complicated in the animal world.