Body

Membrane proteins are responsible for transporting chemicals and messages between a cell and its environment. But determining their structure has proved challenging for scientists. A study by UC Santa Barbara's Han Research Group demonstrates a new tool to resolve the structure of membrane-embedded and membrane-associating proteins using the water dynamics gradient they found across and above the lipid bilayer as a unique ruler.

SYDNEY: A team led by scientists at the University of New South Wales has uncovered the genetic secrets of "extremophile" microbes that can survive in water temperatures as low as minus 20 degrees in the saltiest lake in Antarctica.

Deep Lake, about five kilometres from Davis Station, was formed about 3500 years ago, when the Antarctic continent rose, isolating a section of ocean. The water in the 36-metre deep lake is now so salty it remains in liquid form down to a temperature of minus 20 degrees.

STANFORD, Calif. — Researchers at the Stanford University School of Medicine have identified a way to induce the ovaries of some infertile women to produce eggs.

Using the technique, clinicians at the St. Marianna University School of Medicine in Kawasaki, Japan, collected viable eggs from five women with a condition called primary ovarian insufficiency. One of these women has given birth to a healthy baby, and another is pregnant.

The joint study by Luca Giuggioli and Jonathan Potts from the University of Bristol, and Daniel Rubenstein and Simon Levin from Princeton University shows that animals deposit marks wherever they go to show their presence, and retreat from marks left by a member of the same species more quickly if the encountered mark is recent.

The study published today [30 September] in the Proceedings of the National Academy of Sciences (PNAS) has important implications for how epidemic disease spreads and animal sociality.

Naked mole rats have what any animal would want. They live long lives—about 30 years—and stay healthy until the very end. Now biologists at the University of Rochester have new insights into the animal's longevity—better-constructed proteins.

Sequestered in Antarctica's Vestfold Hills, Deep Lake became isolated from the ocean 3,500 years ago by the Antarctic continent rising, resulting in a saltwater ecosystem that remains liquid in extreme cold, and providing researchers a unique niche for studying the evolution of the microbes that now thrive under such conditions. Deep Lake's microscopic inhabitants are dominated by haloarchaea, microbes that require high salt concentrations to grow and are naturally adapted to conditions – at minus 20°C – that would prove lethally cold to other organisms.

DURHAM, N.C. – By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases.

The insights, reported online the week of Sept. 30, 2013, in the journal Proceedings of the National Academy of Sciences, build on earlier work by the research team and identify new prospects for developing cancer therapies.

The aerosolized dust created by vacuums contain bacteria and mold that "could lead to adverse effects in allergic people, infants, and people with compromised immunity," according to researchers at the University of Queensland and Laval University. Their findings are published ahead of print in Applied and Environmental Microbiology.

Younger patients with colorectal cancer that has spread to other parts of the body represent a high-risk group that is less likely to respond to treatment. Colorectal cancer in patients younger than 40 is more likely to grow despite treatment and young patients are at greater risk of death than people in other age groups.

That's according to research presented to the 2013 European Cancer Congress in Amsterdam. The team of scientists is led by an investigator at University of Colorado Cancer Center.

A mix of serendipity and dogged laboratory work allowed a diverse team of University of Pittsburgh scientists to report in the Oct. 1 issue of Nature Cell Biology that they had solved the mystery of a basic biological function essential to cellular health.

It's often said that the HIV/AIDS epidemic has a woman's face. The proportion of women infected with HIV has been on the rise for a decade; in sub-Saharan Africa, women constitute 60 percent of people living with disease. While preventative drugs exist, they have often proven ineffective, especially in light of financial and cultural barriers in developing nations.

More Hispanic Texans die from cancer than any other cause, according to a new report by the Comparative Effectiveness Research on Cancer in Texas research group.

The report documents cancer as the leading cause of death among Hispanic Texans under the age of 76. Only three percent of Hispanic Texans are older than 75.

Texas's Hispanic population has more than doubled since 1990. Texans of Hispanic ethnicity now comprise 38 percent of the state's population.

New Rochelle, NY, September 30, 2013—Many factors can affect blood sugar control at high altitudes, and people considering a mountain journey need to understand the potential risks of the environmental extremes, extensive exercise, and dietary changes they may experience. Insulin needs may increase or decrease and individuals with poorly controlled diabetes are especially at risk for hypothermia, frostbite, and dehydration, for example.

Similar to using Python or Java to write code for a computer, chemists soon could be able to use a structured set of instructions to "program" how DNA molecules interact in a test tube or cell.

(TORONTO, Canada; Sept. 30, 2013) – Canada should begin screening 'Baby Boomers' for the hepatitis C virus infection, since this age group is likely the largest group to have the illness, and most don't know they have it, say a group of liver specialists in the Toronto Western Hospital Francis Family Liver Clinic. Unlike many other chronic viral infections, early treatment makes hepatitis C curable.