Body

Why do humans pig out?

Researchers from University of Copenhagen have discovered big differences in the variability of eating habits among pigs. The newly published study showed that for some (pigs with certain genetic variants) overeating was normal behavior and for a particular group of pigs there was clear evidence they were genetically programmed to eat more food than others. The study was led by professor Haja Kadarmideen and is the first study in the world looking at pig to human comparative genetic mapping to reveal key genes on the human genome that are known to be involved in human obesity.

Rare research into false killer whales reveals anti-predator partnerships

False killer whales (Pseudorca crassidens) are one of the least studied species of ocean dolphin, but new light has been cast on their behavior by a team of marine scientists from New Zealand. The research, published in Marine Mammal Science, reveals how a population off the coast of New Zealand has developed a relationship with bottlenose dolphins to defend themselves from predation.

Great potential for faster diagnoses with new method

The more accurately we can diagnose a disease, the greater the chance that the patient will survive. That is why many researchers are working to improve the quality of the diagnostic process. Researchers at the Nano-Science Center, University of Copenhagen have discovered a method that will make the process faster, cheaper and more accurate. This is possible, because they are combining advanced tools used in physics for research in biology at nanoscale, two scientific disciplines usually very distant from each other.

5 regular meals a day reduce obesity risk among adolescents

A regular eating pattern may protect adolescents from obesity, according to a Finnish population-based study with more than 4,000 participants. When eating five meals – breakfast, lunch, dinner and two snacks – a day, even those with a genetic predisposition to obesity had no higher body mass index (BMI) than their controls.

Scripps Florida scientists identify potential new drug for inherited cancer

JUPITER, FL, October 3, 2013 – Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure.

The new study showed the drug candidate—known as FRAX97—slowed the proliferation and progression of tumor cells in animal models of Neurofibromatosis type 2. This inherited type of cancer, caused by mutations in the anti-tumor gene NF2, leads to tumors of the auditory nerve that connects the inner ear to the brain.

Cats adapt food selection to meet demands of lactation

Portland, Ore., USA (October 3, 2013) --- Lactating cats not only increase their total calorie consumption, they also significantly alter the make-up of their diet to meet the demands of feeding a litter, research from the WALTHAM® Centre for Pet Nutrition has shown. The research provides intriguing insights into cats' feeding behaviour and strong evidence that they are able to adapt their macronutrient intake, i.e. their intake of protein, fat and carbohydrate, to meet their physiological requirements.

Advanced technology for gene expression analysis can facilitate drug development

When developing new drugs, monitoring cellular responses to candidate compounds is essential for assessing their efficacy and safety. Researchers from the RIKEN Center for Life Science Technologies report a new method to monitor and quantify the activity of gene promoters during the response to a drug, using the advanced gene expression analysis method CAGE followed by single-molecule sequencing. This research paves the way to a more precise analysis of cellular responses to drugs, at the level of individual promoters.

Component of citrus fruits found to block the formation of kidney cysts

A new study published today in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts.

Known as polycystic kidney disease, this is an inherited disorder which leads to the loss of kidney function, high blood pressure and the need for dialysis. Few treatment options are currently available.

International study shows efficacy of new gastric cancer drug

Barcelona, 03 October 2013. This international trial, published in The Lancet, is one of the largest phase III trials in second-line treatment of gastric cancer. Standard care for advanced gastric cancer, known as first-line treatment, is based on chemotherapy, but it only offers a median survival of 8 to 10 months.

Insects modify mating behavior in anticipation of storms

Insects modify calling and courting mating behavior in response to changes in air pressure, according to results published October 2 in the open-access journal PLOS ONE by Ana Cristina Pellegrino and José Maurício Bento, University of São Paulo, and colleagues from other institutions. The bugs' ability to predict adverse weather conditions may help them modify their mating behavior during high winds and rain, reducing risk of injury or even death.

'Cupcake bans' rare, but policies may reduce overexposure to sugary treats

Nearly 1 in 3 American children are overweight or obese, but sugary sweets are often on the menu at elementary school classroom parties.

But schools with a district policy or state law discouraging sugary foods and beverages were 2.5 times more likely to restrict those foods at parties than were schools with no such policy or law, according to a new study published online in the Journal of Nutrition Education and Behavior.

Depression may increase your risk of Parkinson's disease

MINNEAPOLIS -- People who are depressed may have triple the risk of developing Parkinson's disease, according to a study published in the October 2, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

"Depression is linked in other studies to illnesses such as cancer and stroke," said study author Albert C. Yang, MD, PhD, with Taipei Veterans General Hospital in Taipei, Taiwan. "Our study suggests that depression may also be an independent risk factor for Parkinson's disease."

High-dose statins reduce gum inflammation in heart disease patients

WASHINGTON (Oct. 2, 2013) — Statins, commonly prescribed medications for lowering cholesterol, also reduced inflammation associated with gum disease in a new study published today in the Journal of the American College of Cardiology. The study suggests that steps taken to reduce gum disease may also reduce inflammation in the arteries and vice versa.

New MRI technique can detect genetic condition that attacks the heart, brain and nerves

A genetic condition that attacks multiple organs and usually results in fatal heart problems can be detected using a new MRI technique that was developed at the University of Alberta. The discovery of this new diagnostic tool has resulted in updated clinical guidelines for the diagnosis and treatment of Fabry disease in Canada.

Scripps Florida scientists shed light on body's master energy regulator

JUPITER, FL – October 2, 2013 – Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered some key features that explain just what turns on a protein that is considered to be a master regulator of how the human body uses and stores energy.

The new discoveries could help in the design and development of new therapeutics to treat metabolic disease such as diabetes and obesity—and perhaps some cancers as well.