Body

'Test and Treat' model offers new strategy for eliminating malaria

As researchers work to eliminate malaria worldwide, new strategies are needed to find and treat individuals who have malaria, but show no signs of the disease. The prevalence of asymptomatic or minimally symptomatic malaria can be as high as 35 percent in populations with malaria and these asymptomatic individuals can serve as a reservoir for spreading malaria even in areas where disease transmission has declined.

PET techniques provide more accurate diagnosis, prognosis in challenging breast cancer cases

Reston, Va. -- In two new studies featured in the February issue of the Journal of Nuclear Medicine, researchers are revealing how molecular imaging can be used to solve mysteries about difficult cases of breast cancer. One article focuses on an imaging agent that targets estrogen receptors in estrogen receptor–positive breast cancer patients with formerly inconclusive assessments, and the second highlights a different imaging agent's ability to help predict the prognosis for patients undergoing chemotherapy for a very aggressive type of breast cancer.

Injectable progesterone contraceptives may be associated with poor periodontal health

Chicago -- Injectable progesterone contraceptives may be associated with poor periodontal health, according to research in the Journal of Periodontology. The study found that women who are currently taking depotmedroxyprogesterone acetate (DMPA) injectable contraceptive, or have taken DMPA in the past, are more likely to have indicators of poor periodontal health, including gingivitis and periodontitis, than women who have never taken the injectable contraceptive. DMPA is a long-lasting progestin-only injectable contraceptive administered intermuscularly every three months.

Discovery predicts patient sensitivity to important drug target in deadly brain cancer

Grand Rapids, Mich. – A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma – the most common and most aggressive malignant brain tumor in humans.

The study, published in January in the Proceedings of the National Academy of Science, investigated glioblastoma models characterized by cell signaling activation and gene amplification for their susceptibility to inhibitors of both the human MET oncogene and the epidermal growth factor receptor (EFGR).

Odds of living a very long life lower than formerly predicted

Research just published by a team of demographers at the social science research organization NORC at the University of Chicago contradicts a long-held belief that the mortality rate of Americans flattens out above age 80.

It also explains why there are only half as many people in the U.S. age 100 and above than the Census Bureau predicted there would be as recently as six years ago.

Satellite tracking reveals sea turtle feeding hotspots

GAINESVILLE, Fla. – Satellite tracking of threatened loggerhead sea turtles has revealed two previously unknown feeding 'hotspots' in the Gulf of Mexico that are providing important habitat for at least three separate populations of the turtles, according to a study published recently in the journal Biological Conservation.

The two sites, located in the open waters off the coast of Southwest Florida and the northern tip of the Yucatan Peninsula, were found by a team of scientists when they compiled and analyzed loggerhead tracking data.

New Centre for Consumer Science report on Christmas gifts

The stereotypical Christmas gift shopper is a stressed-to-the-max individual with a filled-to-the-rim shopping cart in a busy shopping mall. The shopping hysteria during the weeks before Christmas is frequently debated in the media, and the seeming overflow of just about everything is often viewed as immoral.

Researchers examine consequences of non-intervention for infectious disease in African great apes

(Santa Barbara, Calif.) –– Infectious disease has joined poaching and habitat loss as a major threat to the survival of African great apes as they have become restricted to ever-smaller populations. Despite the work of dedicated conservationists, efforts to save our closest living relatives from ecological extinction are largely failing, and new scientific approaches are necessary to analyze major threats and find innovative solutions.

Consumers willing to buy sustainable US cotton, MU researchers find

COLUMBIA, Mo. – As the interest in environmentally responsible business practices grows globally, researchers are interested in how that interest translates into consumer sales. Researchers from the University of Missouri have found that United States consumers are more willing to buy clothing made from sustainably grown U.S. cotton than apparel produced using conventional practices in an unknown location. Jung Ha-Brookshire, an assistant professor in the textile and apparel management department in the College of Human Environmental Sciences at MU, says transparency is the key.

Heart hormone helps shape fat metabolism

ORLANDO, Fla., February 6, 2012 – It's well known that exercising reduces body weight because it draws on fat stores that muscle can burn as fuel. But a new study at Sanford-Burnham Medical Research Institute (Sanford-Burnham) suggests that the heart also plays a role in breaking down fat. In their study, published February 6 in the Journal of Clinical Investigation, Sheila Collins, Ph.D. and colleagues detail how hormones released by the heart stimulate fat cell metabolism.

Hormel Institute study makes key finding in stem cell self-renewal

A University of Minnesota-led research team has proposed a mechanism for the control of whether embryonic stem cells continue to proliferate and stay stem cells, or differentiate into adult cells like brain, liver or skin.

The work has implications in two areas. In cancer treatment, it is desirable to inhibit cell proliferation. But to grow adult stem cells for transplantation to victims of injury or disease, it would be desirable to sustain proliferation until a sufficient number of cells have been produced to make a usable organ or tissue.

Scientists make strides toward fixing infant hearts

HOUSTON -- (Feb. 6, 2012) -- Researchers at Rice University and Texas Children's Hospital have turned stem cells from amniotic fluid into cells that form blood vessels. Their success offers hope that such stem cells may be used to grow tissue patches to repair infant hearts.

Study shows electron-beam irradiation reduces virus-related health risk in lettuce, spinach

COLLEGE STATION – A team of scientists studying the effects of electron-beam irradiation on iceberg lettuce and spinach has had its research published in the February issue of the leading microbiology journal, Applied and Environmental Microbiology, said the study's lead investigator.

The study quantified the theoretical health-risk reduction from virus-related foodborne illness through the use of electron-beam irradiation.

Nanorod-assembled order affects diffusion rate and direction

Some of the recent advancements in nanotechnology depend critically on how nanoparticles move and diffuse on a surface or in a fluid under non-ideal to extreme conditions. Georgia Tech has a team of researchers dedicated to advancing this frontier.

'ROCK' off: Study establishes molecular link between genetic defect and heart malformation

CHAPEL HILL, N.C. – UNC researchers have discovered how the genetic defect underlying one of the most common congenital heart diseases keeps the critical organ from developing properly. According to the new research, mutations in a gene called SHP-2 distort the shape of cardiac muscle cells so they are unable to form a fully functioning heart.