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DENVER –Two studies are providing new insight into germline epidermal growth factor receptor (EGFR) T790M mutation in familial non-small cell lung cancer (NSCLC). The findings suggest the need for tailored approaches for early detection and treatment, as well as for genetic testing to identify carriers.

The poor prognosis for pancreatic cancer, where only 5 percent of the patients survive five years after the diagnosis, is due to the fact that the tumors often develop unnoticed, and rarely cause symptoms until they have spread to other organs. Recent studies, however, have shown that fluid-filled compartments in the pancreas, called cysts, may be precursors of the cancer.

Cysts in the pancreas, which are found in every 10th person above the age of 70, and are also common in younger people, can be discovered with computed tomography (CT) or magnetic resonance imaging (MRI).

Alexandria, Va., USA – Today during the 43rd Annual Meeting & Exhibition of the American Association for Dental Research, held in conjunction with the 38th Annual Meeting of the Canadian Association for Dental Research, Craig Miller, University of Kentucky, Lexington, will present research titled "Salivary Biomarkers of Gingivitis: Information Important for Personalized Decision-Making."

Alexandria, Va., USA – Today during the 43rd Annual Meeting & Exhibition of the American Association for Dental Research, held in conjunction with the 38th Annual Meeting of the Canadian Association for Dental Research, Daniel Huy Nguyen, The Forsyth Institute, Cambridge, Mass., will present research titled "Novel Pro-Resolving-Medicines in Periodontal Regeneration."

Listeria is a rod-shaped bacterium highly prevalent in the environment and generally not a threat to human health. One species however, Listeria monocytogenes, can cause listeriosis, a very dangerous disease. This pathogen can be present in raw milk and soft cheeses, smoked fish, raw meat and ready-to-eat products. In Austria, health care providers are required to report all cases of listeriosis, which can be fatal particularly for patients with weakened immune systems.

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis – and has identified for the first time through genetic evidence that a single bacteria could be the cause.

Researchers at LSTM have discovered how unprecedented multiple and extreme-level resistance is generated in mosquitoes found in the rice fields of Tiassalé in southern Côte d'Ivoire.

Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion. For the successful control of cell movement, this process has to be determined and maintained with great precision. In this study, the scientists used tracheal cells of the fruit fly Drosophila melanogaster to unravel the signalling mechanism involved in the regulation of cell movements.

This news release is available in German.

Icahn School of Medicine at Mount Sinai researchers have linked high levels of exposure to inhaled particulate matter by first responders at Ground Zero to the risk of obstructed sleep apnea and post-traumatic stress disorder (PTSD), both conditions that may impact cardiovascular health.

Philadelphia, PA, March 21, 2014 – Chronically ill adults who reported food insecurity in their household (not having consistent access to food due to lack of financial stability) were significantly more likely to report cost-related medication underuse, according to a new study in The American Journal of Medicine,. The term cost-related medication underuse refers to taking less medication than prescribed, or not taking it at all due to financial concerns.

Pohang, Republic of Korea, March 21, 2014 – Earlier today, Korean researchers successfully showcased the installation and operation of a box-shaped, high-pressure tank for the storage of liquefied natural gas in Pohang, Republic of Korea. The development was the first of its kind in the world.

Happiness makes people more productive at work, according to the latest research from the University of Warwick.Economists carried out a number of experiments to test the idea that happy employees work harder. In the laboratory, they found happiness made people around 12% more productive.

Professor Andrew Oswald, Dr Eugenio Proto and Dr Daniel Sgroi from the Department of Economics at the University of Warwick led the research.

Northwestern Medicine scientists have demonstrated that cancer cells – and not normal cells – can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand.

"The discovery seems counterintuitive because CD95 has previously been defined as a tumor suppressor," said lead investigator Marcus Peter, professor in medicine-hematology/Oncology at Northwestern University Feinberg School of Medicine. "But when we removed it from cancer cells, rather than proliferate, they died."

Irvine, Calif., March 20, 2014 — Hematopoietic stem cells are now routinely used to treat patients with cancers and other disorders of the blood and immune systems, but researchers knew little about the progenitor cells that give rise to them during embryonic development.